Protein

MIA_04176_1

Length
556 amino acids

Browser: contig05:980851-982715-

Protein function

EGGNOG:0PHV8FG08485.1EH domain binding protein epsin 2
SGD closest match:S000002320ENT1Epsin-1
CGD closest match:CAL0000186455orf19.1444Epsin

Protein alignments

%idAln lengthE-value
MCA_00128_160.484%3723.20e-93MCA_00128_1
A0A161HFX2_9ASCO66.418%1344.90e-57Ent2p OS=Sugiyamaella lignohabitans GN=ENT2 PE=4 SV=1
A0A060T3K2_BLAAD64.179%1342.98e-57ARAD1A10384p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A10384g PE=4 SV=1
A0A1E3PLC2_9ASCO66.165%1332.52e-53ENTH-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82728 PE=4 SV=1
UniRef50_A0A1E3PLC266.165%1336.83e-50ENTH-domain-containing protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PLC2_9ASCO
A0A0J9X2D5_GEOCN64.662%1336.72e-53Similar to Saccharomyces cerevisiae YLR206W ENT2 Epsin-like protein required for endocytosis and actin patch assembly and functionally redundant with Ent1p OS=Geotrichum candidum GN=BN980_GECA01s00384g PE=4 SV=1
Q6C7P2_YARLI61.654%1331.13e-50YALI0D26510p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D26510g PE=4 SV=1
A0A1D8PGB7_CANAL60.000%1351.73e-45Epsin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1444 PE=1 SV=1
ENT1_YEAST57.895%1331.93e-44Epsin-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ENT1 PE=1 SV=1
A0A1E4TKZ5_9ASCO55.208%965.86e-32Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30596 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7906
Predicted cleavage: 26

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 556

Detailed signature matches

  1. Domain IPR008942
    ENTH/VHS
    1. SSF48464 (ENTH/VHS ...)
    2. G3DSA:1.25.40.90
  2. Domain IPR013809
    ENTH domain
    1. PF01417 (ENTH)
    2. PS50942 (ENTH)
    3. SM00273 (enth_2)
  3. SITE IPR003903
    Ubiquitin interacting motif
    1. SM00726 (uim)
    2. PS50330 (UIM)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd03571 (ENTH_epsin)
  4. mobidb-lite (disord...)

Residue annotation

  1. Ins(1,4,5)p3 bindi...
  2. PLZF binding site ...

Protein sequence

>MIA_04176_1
MSKSLVRSIKNVTSGYTSTQVKVRNATSNEPVGPTSQELHELAQLTYQNHEVLEVMGMLTQRLNDKGKNWRHVMKSLTVL
EFLLLNGSEAVVLWAKENLYLIKTLCEFQYHDDSDIDQGQNVRARAKALTALLQDDDRLRHERRERRGRNGRRRHGDYDN
EFDDSRNRGPRSTSRRRESRRPSRVPAEDDEMRRALEESRITAEEEEAARRQRLNADDNDDDLRQALMLSREEDEQRRLD
QEKAFQINKQNENLIDLTAPAVQQPQVAVQYQFTTQPAYVTGQYDQFGNPVNGALYQQPVTTGYIQNMYSVDGQYTGYPA
QQQQVLYQQPTGAFSSQFSQQQVQPEQQQPLAPMKTGSNNPFAKLTNQPATTYTGPSLNDIQQQKQLEQQQQQQQQQQQY
YLQQQQQQQQQQLQQQQLQQQQQQQQQQQQQQPLKAVHTGRSEHVEELNTLLATGTGLDTFGNTGDLRIPAQHTRSQFIN
SQGTGYQAGFQQAQTTNNPFMGAQYTGVPSTNPIQPAFTGYGFGNAQQSQQSYQQQQQQQQRQQYAYGGQQSLIDI

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.