Protein

MIA_04153_1

Length
341 amino acids

Browser: contig05:916899-917925-

Protein function

EGGNOG:0PFR4Alcohol dehydrogenase GroES-like domain
SGD closest match:S000004688ADH3Alcohol dehydrogenase 3, mitochondrial
CGD closest match:CAL0000177934ADH5Adh5p

Protein alignments

%idAln lengthE-value
MCA_00096_175.811%3390.0MCA_00096_1
UniRef50_A2V8B351.662%3314.09e-112N-benzyl-3-pyrrolidinol dehydrogenase n=1 Tax=Magnusiomyces capitatus TaxID=1095183 RepID=A2V8B3_9ASCO
A0A0J9YHL2_GEOCN48.949%3335.58e-110Similar to Saccharomyces cerevisiae YOL086C ADH1 Alcohol dehydrogenase OS=Geotrichum candidum GN=BN980_GECA01s06104g PE=3 SV=1
A0A060T2K2_BLAAD45.104%3375.39e-86ARAD1C32934p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32934g PE=4 SV=1
A0A1D8PS45_CANAL41.194%3358.21e-82Adh5p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADH5 PE=3 SV=1
A0A1E4TMA4_9ASCO44.848%3301.66e-80Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56443 PE=3 SV=1
A0A1E3PR81_9ASCO30.252%3572.99e-37GroES-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48590 PE=3 SV=1
ADH3_YEAST29.345%3516.44e-35Alcohol dehydrogenase 3, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH3 PE=1 SV=2
Q6CGT5_YARLI30.286%3506.23e-35YALI0A16379p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A16379g PE=3 SV=1
A0A167FJP5_9ASCO29.799%3491.51e-33Alcohol dehydrogenase ADH3 OS=Sugiyamaella lignohabitans GN=ADH3 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5194
Predicted cleavage: 43

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
  4. Domain
1 50 100 150 200 250 300 341

Detailed signature matches

  1. Domain IPR011032
    GroES-like
    1. SSF50129 (GroES-like)
  2. Domain IPR020843
    Polyketide synthase, enoylreductase domain
    1. SM00829 (PKS_ER_nam...)
  3. Domain IPR013154
    Alcohol dehydrogenase, N-terminal
    1. PF08240 (ADH_N)
  4. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  5. Domain IPR013149
    Alcohol dehydrogenase, C-terminal
    1. PF00107 (ADH_zinc_N)
  6. SITE IPR002328
    Alcohol dehydrogenase, zinc-type, conserved site
    1. PS00059 (ADH_ZINC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. G3DSA:3.90.18...
  3. cd08254 (hydroxyacy...)

Residue annotation

  1. catalytic Zn bindi...
  2. putative NAD(P) bi...
  3. structural Zn bind...

Protein sequence

>MIA_04153_1
MSTQFTIPKTQTAWFYKPGSNALHKRTIPVPTPPPGSVLLRIDAAGVCHSDLHILHGGIPYNAEFIPGHEIAGTVVALGS
SVDPRQFPIGTRYAVHSQNACGLCGLCRSGHDNICQAKTRLQIGLGHPGGYEEYTALPIRNLIRIPDNVPTEIAAVATDA
VLTPYHALKKAQINGSTRLLVLGLGGLGINAVQIAKAWGAHVTAMDPRADARELALQSGADAVLEKFPSRSLNFDVVADF
AGVKSSFDMAQKHVRHLGTILTVGMGANITEYQNTKMSYKEMTTIGSLGGTTQDLAECLEMISKGVIKPQIEENKLNDVN
NVLQRLDKGQATARLVLKASL

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.