Protein

MIA_04043_1

Length
453 amino acids


Browser: contig05:592457-594040+

Protein function

EGGNOG:0PJ65TCRP4-hydroxyphenylpyruvate dioxygenase
CGD closest match:CAL0000180732orf19.5499Uncharacterized protein

Protein alignments

%idAln lengthE-value
UniRef50_B8LV5852.106%4511.25e-1504-hydroxyphenylpyruvate dioxygenase n=20 Tax=leotiomyceta TaxID=716546 RepID=B8LV58_TALSN
A0A1E4TKE5_9ASCO51.351%4441.20e-1514-hydroxyphenylpyruvate dioxygenase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_84118 PE=3 SV=1
MCA_00040_147.737%4864.68e-150MCA_00040_1
A0A167DUP1_9ASCO52.667%4503.01e-1504-hydroxyphenylpyruvate dioxygenase OS=Sugiyamaella lignohabitans GN=AWJ20_1597 PE=3 SV=1
A0A060T2L2_BLAAD51.678%4474.88e-1474-hydroxyphenylpyruvate dioxygenase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C33286g PE=3 SV=1
HPPD_YARLI49.663%4452.97e-1454-hydroxyphenylpyruvate dioxygenase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0B21846g PE=3 SV=1
A0A0J9X882_GEOCN49.333%4506.14e-1394-hydroxyphenylpyruvate dioxygenase OS=Geotrichum candidum GN=BN980_GECA05s04630g PE=3 SV=1
A0A1D8PHL9_CANAL39.286%2521.67e-51Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5499 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2028
Predicted cleavage: 27

Protein family membership

Domains and repeats

Detailed signature matches

    1. PIRSF009283 (4HPP_d...)
    1. SSF54593 (Glyoxalas...)
    1. PF00903 (Glyoxalase)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd07250 (HPPD_C_like)
  2. cd08342 (HPPD_N_like)

Residue annotation

  1. dimer interface cd...
  2. Fe binding site cd...
  3. active site cd07250

Protein sequence

>MIA_04043_1
MAIETIQQSNYTGYSHVTWYVSNARQAASYMITRMGFEQVAYRGLETGSRSIAAHVVGNGAVRFVFISVLRSETRMEKGH
ENDIELVREINDHIKKHGDGVKDVAFVVNDLDALFKSAVENGAQIVKPPYVLEDESGYVRQAVVQTYGDTTHTLVEYIDR
KTGQPTYRGDFLPGYSSPRPESKDPINLILPVVSLVRIDHCVGNQDKNQMEDVCKYYERALGFRRFWSVDDSQVHTEYSA
LRSVVMSSGGPDVIKMPINETAPGKKRSQIEEFVEYYDGPGVQHIALLTEDIVAAVSSMKTHRGVGFIAVPHAYYEMLAL
RLAEKGLGMLHIKDAAIEVENVNVATTGAANSAATSLEIRAPEISHLSFAEKRLEIPYSYAIPQSLKMLEDLGILVDFDE
NGYLLQTFTRPLGDRPTVFIEIIQRMNHNGFGAGNFRALFEAIERDQSARGNL

GO term prediction

Biological Process

GO:0009072 aromatic amino acid family metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity
GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen

Cellular Component

None predicted.