Protein

MIA_03504_1

Length
305 amino acids


Browser: contig04:1384753-1385671-

Protein function

EGGNOG:0PKDI)-reductase
SGD closest match:S000002282YDL124WNADPH-dependent alpha-keto amide reductase
CGD closest match:CAL0000193623orf19.1340Aldo-keto reductase superfamily protein

Protein alignments

%idAln lengthE-value
MCA_03638_146.980%2981.81e-90MCA_03638_1
A0A167F202_9ASCO48.432%2876.24e-86Aldo-keto reductase superfamily protein OS=Sugiyamaella lignohabitans GN=AWJ20_2330 PE=4 SV=1
UniRef50_A0A167F20248.432%2871.71e-82Aldo-keto reductase superfamily protein n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167F202_9ASCO
A0A1E3PR25_9ASCO43.377%3021.37e-78Putative NADPH-dependent alpha-keto amide reductase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49731 PE=4 SV=1
A0A0J9X9A1_GEOCN45.333%3009.15e-76Similar to Saccharomyces cerevisiae YDL124W NADPH-dependent alpha-keto amide reductase, reduces aromatic alpha-keto amides, aliphatic alpha-keto esters,and aromatic alpha-keto esters OS=Geotrichum candidum GN=BN980_GECA06s00274g PE=4 SV=1
Q6CEJ0_YARLI39.262%2986.69e-72YALI0B15268p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15268g PE=4 SV=1
A0A1E4TF31_9ASCO39.604%3035.39e-65Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_147963 PE=4 SV=1
A0A1D8PRB0_CANAL41.463%2871.22e-61Aldo-keto reductase superfamily protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1340 PE=4 SV=1
KAR_YEAST40.411%2921.29e-60NADPH-dependent alpha-keto amide reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDL124W PE=1 SV=1
A0A060T5D7_BLAAD34.459%2961.36e-43ARAD1B10230p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10230g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4841
Predicted cleavage: 36

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 305

Detailed signature matches

    1. PR00069 (ALDKETRDTASE)
    1. SSF51430 (NAD(P)-li...)
    2. cd06660 (Aldo_ket_red)
    3. PF00248 (Aldo_ket_red)
    1. PS00062 (ALDOKETO_R...)

Residue annotation

  1. active site cd06660
  2. catalytic tetrad c...

Protein sequence

>MIA_03504_1
MTTIPNGTLSNGVKIPFLAYGAGTVWSKWRLRTRGVAVPETGIYQPVVDAVLAALRAGHRHIDTAEFYETEEEVGLALEQ
FLRETPSLSRKDIFITTKIWKYAADPDTAVAESLRKLRVDYVDLYLIHSPDLAKFNAKVEVVWPKLEEFYKQGKARAIGV
SNFSVKDLEYLKTFAKVTPHANQIEYSPYQQDPSPGLVEYLYKNNILIEAYGPLGAITVDNYATAPLTPVLERLAKKYNK
TPAQLSLRWVYQTNVLPVTTSTKPDRLNESLDIFSFSLSEDEVSEITTVSKAYQYHRYASSNTKP

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.