Protein

MIA_03413_1

Length
757 amino acids


Browser: contig04:1155026-1157534-

Protein function

EGGNOG:0PHIQFG06940.1calcium calmodulin-dependent protein kinase
SGD closest match:S000000931SAK1SNF1-activating kinase 1
CGD closest match:CAL0000198568orf19.3840Serine/threonine protein kinase

Protein alignments

%idAln lengthE-value
MCA_03133_160.642%5920.0MCA_03133_1
A0A0J9XHQ4_GEOCN56.480%5170.0Similar to Saccharomyces cerevisiae YGL179C TOS3 Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p OS=Geotrichum candidum GN=BN980_GECA17s00571g PE=4 SV=1
UniRef50_A0A0J9XHQ456.480%5171.77e-179Similar to Saccharomyces cerevisiae YGL179C TOS3 Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHQ4_GEOCN
A0A167FGM1_9ASCO50.688%5091.55e-142Serine/threonine protein kinase TOS3 OS=Sugiyamaella lignohabitans GN=TOS3 PE=4 SV=1
Q6CE90_YARLI47.799%4772.04e-142YALI0B17556p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B17556g PE=4 SV=1
A0A060T3J4_BLAAD46.184%5111.55e-138ARAD1C33946p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C33946g PE=4 SV=1
A0A1E4TF48_9ASCO38.903%4011.94e-78Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_25343 PE=4 SV=1
A0A1E3PS15_9ASCO39.943%3534.82e-69Glycylpeptide N-tetradecanoyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_63678 PE=3 SV=1
Q5A650_CANAL31.360%4568.41e-44Serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3840 PE=4 SV=1
SAK1_YEAST30.056%3562.86e-40SNF1-activating kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAK1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0202
Predicted cleavage: 40

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 757

Detailed signature matches

    1. SSF56112 (Protein k...)
    1. PS50011 (PROTEIN_KI...)
    2. PF00069 (Pkinase)
    3. SM00220 (serkin_6)
    1. PS00107 (PROTEIN_KI...)
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd14008 (STKc_LKB1_...)
  2. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. active site cd14008
  3. polypeptide substr...
  4. activation loop (A...

Protein sequence

>MIA_03413_1
MLSHHHPAAPTAAPDRGPPGICYPHSSNAASGPAAFARPHSLQPPPHNISGLTQPSAALQPGSLPHSPYLAPHISLSMTE
RPTAPGDPSEACQNENAPTPCVVLPVPGAGTSNTLHANSSLNPPVTGPPPISNNPLARRPSMVRFYSTPTLPCMSPTRQQ
FRLANATPRQIKETVVSSRRVDDAGKTVNQYLVCGQIGCGTFGTVWKVTDTNTSEPYAMKEYSKSSLRKHLRSELLSQRR
RAVMRGSSRPRTPLAGVSTSSISPAIDNNSPFNLIRREFAIAKKLDHPNIVSLIEVLDDPESDSLYLILEWCANGPVMSH
TKTRNNDDHQPPLVPTACLSEEQCRLYFRDMILGIEYLHSQGVIHRDIKADNLLLDEDDVLKIADFGVSELFEQDNDVIT
KTAGSPSYMAPELAVISNGALMPLAATRDIPINSLSGRSADIWSMGVTLYYMLFGVLPFRADNVMDLYTRIVTEDVEFPR
EDINPDLKDLFARILCKSPPKRIKMDELRIHPWVTHRNQDALVSKEENISDSITQVTEEDISSAIERVRSLGVEPEHAMA
KLRKLHGWRGQPSSRSSSRSPSLSPYLAPHDALARVPSPTQPLDDTNLSLQKLTRALEEVARRSQSKSRTGATGSTGGPG
SSSYYNNSNSGGLSSNHSYYQGLNATPGGPSAGSSIYPSRNPSTNVSLLSVAIMDDPTEPDATLKEENTVTIMGRPPTAP
SPTSPTSDTPPSPPSLKTAAPSACNLVHESASTHISL

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.