Protein

MIA_03240_1

Length
198 amino acids

Browser: contig04:639924-640521+

Protein function

EGGNOG:0PQA9DFG103-oxo-5-alpha-steroid 4-dehydrogenase
SGD closest match:S000001311DFG10Polyprenol reductase
CGD closest match:CAL0000191358DFG10Putative polyprenol reductase

Protein alignments

%idAln lengthE-value
A0A1E3PGL6_9ASCO36.691%1393.70e-19Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_14448 PE=4 SV=1
UniRef50_A0A1E3PGL636.691%1391.00e-15Uncharacterized protein (Fragment) n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PGL6_9ASCO
A0A060TFF6_BLAAD35.714%1263.75e-17ARAD1D22858p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22858g PE=4 SV=1
A0A0J9X5H4_GEOCN35.503%1696.27e-17Similar to Saccharomyces cerevisiae YIL049W DFG10 Probable polyprenol reductase that catalyzes conversion of polyprenol to dolichol OS=Geotrichum candidum GN=BN980_GECA03s05345g PE=4 SV=1
Q6C6N9_YARLI35.862%1451.27e-16YALI0E07788p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E07788g PE=4 SV=1
MCA_01256_127.670%2063.50e-16MCA_01256_1
A0A1D8PIB6_CANAL33.526%1732.06e-12Putative polyprenol reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DFG10 PE=4 SV=1
DFG10_YEAST30.075%1332.65e-12Polyprenol reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DFG10 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7228
Predicted cleavage: 146

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 140 160 180 198

Detailed signature matches

  1. Domain IPR001104
    3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
    1. PS50244 (S5A_REDUCTASE)
    2. PF02544 (Steroid_dh)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)

Protein sequence

>MIA_03240_1
MAISLICVFAHNLRRLYECRYIQFKKAAAQSKPATIQLPHFIVGIVFYIIVNSIYFLGLVNDNTNLATKVISAVFYVSLL
LFGVSSYVQYICHVHLSRLVKYSLPSSPSDVPFASKIYAKIACPHYTAEIMVYVSLWGMFPKNRVNSLTWLLLVLWVTAN
LSISAEQTLYYYQKGAKEGLYGDKKSPVPANAIFPPVL

GO term prediction

Biological Process

GO:0006629 lipid metabolic process

Molecular Function

GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors

Cellular Component

GO:0005737 cytoplasm
GO:0016021 integral component of membrane