MIA_03225_1

Protein

Length

695 amino acids

Protein function

EGGNOG:	0QE95	ARG2	N-acetylglutamate synthase involved in arginine biosynthesis (By similarity)
SGD closest match:	S000003607	ARG2	Amino-acid acetyltransferase, mitochondrial
CGD closest match:	CAL0000184037	ARG2	Amino-acid acetyltransferase, mitochondrial

Protein alignments

	%id	Aln length	E-value
MCA_00890_1	59.885%	698	0.0	MCA_00890_1
A0A0J9XBH0_GEOCN	64.229%	629	0.0	Amino-acid acetyltransferase, mitochondrial OS=Geotrichum candidum GN=BN980_GECA09s00109g PE=3 SV=1
NAGS_YARLI	50.621%	644	0.0	Amino-acid acetyltransferase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ARG2 PE=3 SV=1
UniRef50_Q6CEE1	50.621%	644	0.0	Amino-acid acetyltransferase, mitochondrial n=3 Tax=Dipodascaceae TaxID=34353 RepID=NAGS_YARLI
A0A1E3PKR2_9ASCO	46.562%	698	3.01e-179	Amino-acid acetyltransferase, mitochondrial OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83401 PE=3 SV=1
A0A060SYR1_BLAAD	44.838%	649	5.21e-160	Amino-acid acetyltransferase, mitochondrial OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A18986g PE=3 SV=1
A0A167F8E2_9ASCO	45.826%	539	1.38e-139	Acetyl-CoA:L-glutamate N-acetyltransferase OS=Sugiyamaella lignohabitans GN=ARG2 PE=4 SV=1
A0A1E4TAF3_9ASCO	37.294%	606	8.61e-104	Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17154 PE=4 SV=1
NAGS_CANAL	33.073%	641	3.17e-79	Amino-acid acetyltransferase, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ARG2 PE=2 SV=2
NAGS_YEAST	31.034%	464	2.01e-54	Amino-acid acetyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARG2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8208
Predicted cleavage: 41

Protein family membership

N-acetylglutamate synthase, fungal (IPR011190)

Domains and repeats

Domain
482 - 692
Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domain (IPR006855)

1 100 200 300 400 500 600 695

Detailed signature matches

IPR011190

N-acetylglutamate synthase, fungal
1. PIRSF007892 (NAGS_f...)
  
  60 - 250
  
  PIRSF
  PIRSF007892 (NAGS_fungal)
  
  269 - 695
  
  PIRSF
  PIRSF007892 (NAGS_fungal)
IPR006855

Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domain
1. PS51731 (GNAT_NAGS)
  
  502 - 692
  
  PROSITE profiles
  PS51731 (GNAT_NAGS)
2. PF04768 (NAT)
  
  482 - 688
  
  Pfam
  PF04768 (NAT)

no IPR

Unintegrated signatures

G3DSA:3.40.63...

500 - 695

GENE3D
G3DSA:3.40.630.30 (G3DSA:3.40.630.30)
NON_CYTOPLASM... (N...)

25 - 695

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 24

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

20 - 24

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

8 - 19

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 7

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)
mobidb-lite (disord...)

124 - 150

MobiDB Lite
mobidb-lite (disorder_prediction)

35 - 62

MobiDB Lite
mobidb-lite (disorder_prediction)

Protein sequence

>MIA_03225_1
MSIYTTRSLALGSRVVPSLPPALALSATTNRSLHCSAPAPAANHNVAPPEAQDPPEETFIKNSHPAQKSYGLHSTADAKD
LILSVLRSTATKREARQYISRYTPLIGRDSDDIFKRRQFVQDLLKSQDSHHSPPEYPRAPYKSQLSKSPPQALSDSFSAL
DFKHVLRVAIIKIRDIKSIDPETFLKIGHTIVRLTKLGVSPIVVVEAGKERNDFLHLDNQPFRHYERAIMWKAAAVAGAI
ESASSNGSIRARPIEGLFEFKDPNSSETGEIPTNSLSIHNYPNTSPSNSSFPVTNNPLKSYTPVDNSNANRLKFSIPNLI
LLPLSHGIIPVVVPLAYDPVTSEEKLIVADDAVVYLVSQFARHYNHIVSVDKIIFIEPLGGIPSIERDGSHVFVNLTQEL
ADITAELHLGFVDPTTREINLANLRTMDRALSLLPNSASGLITTPAVASLSSSRNPIIYNILTDRPILSPSLPVVRKRTP
TVETTILRKGMPVILMKSLTGIDLIKENKVGSIDLNRLWDLIEKSFGRKLDKEAYLKRINGKVAGIIIAGDYEGAAIITW
EEPSTNNSSSGETDQEPVIISELERIFRAAEEVERPRRVAYLDKFAVHPSSQGASGVADVVFKSMVLTLFPDELLWRSRK
VNPVNKWYFERSKGTLKLPGDSPWCVFWTGLGTREADHLNDYIDICRTIPSSWKD

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0004042 acetyl-CoA:L-glutamate N-acetyltransferase activity

Cellular Component