Protein

MIA_03125_1

Length
900 amino acids


Browser: contig04:295874-298577-

Protein function

EGGNOG:0PFHSPGUG_05398Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity)
SGD closest match:S000000193BRN1Condensin complex subunit 2
CGD closest match:CAL0000196556BRN1Condensin complex subunit 2

Protein alignments

%idAln lengthE-value
A0A060T814_BLAAD48.889%3154.05e-71Condensin complex subunit 2 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32736g PE=3 SV=1
UniRef50_A0A060T81448.889%3151.00e-67Condensin complex subunit 2 n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T814_BLAAD
MCA_04960_147.892%3322.40e-70MCA_04960_1
A0A0J9XBR9_GEOCN51.274%3147.68e-70Condensin complex subunit 2 OS=Geotrichum candidum GN=BN980_GECA09s02023g PE=3 SV=1
Q6CFV1_YARLI44.444%3156.40e-57Condensin complex subunit 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B03476g PE=3 SV=1
A0A1E3PCR0_9ASCO45.020%2514.68e-54Barren-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53441 PE=4 SV=1
A0A1D8PMC8_CANAL40.764%3144.07e-54Condensin complex subunit 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BRN1 PE=3 SV=1
CND2_YEAST47.423%1942.74e-44Condensin complex subunit 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BRN1 PE=1 SV=3
A0A167E8B0_9ASCO48.889%2251.06e-43Condensin complex subunit 2 OS=Sugiyamaella lignohabitans GN=BRN1 PE=3 SV=1
A0A1E4TGN0_9ASCO33.333%2641.74e-27Condensin complex subunit 2 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44552 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2184
Predicted cleavage: 14

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF05786 (Cnd2)
    2. PIRSF017126 (Conden...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_03125_1
MPPITNSKSNNRRRSMRDEQGKDYEGQFNDDEHEKRSRRVNRPTNDPRRQSLGLGNRNVTATPLRNSTTPVPGISTADSP
GFRTVPIMASFEDVMNLVKNNKITESNSWNYQLIDYFHDMSVLKEGDGINFQKASFTLDGCVKIYTSRVDSVTSETTKLL
SGLSEQSGNSKKDGNQEGEDEDESAELRQKSRKRNKGESTLAKDFSEIKAKKLDLELAVDPLFRKVMADFNEGGAHSLLL
NSLSIDGTGRVVFDGQSDANGDAEKESNTAVPPPDTQIPTAQETLNSQENVIQIDLDLLRDRFFPDMEELNDMSVCPSLP
RLEEIVKDPSNSVSIIPDAKTLQMEEADRIEQQQRMMQAGIRTSISSTQPFENQPQYSHTNADDDDDMVDGGAFIQQKLT
EKIPGAENMEGETQYNGDNDYGGDYGNDFGDYGGNDDDDDGDVGAFGLIGPEVDGEVTFGEPDVPTQKPINEDVDMEESK
QMEEKSMELNEEKGQEAFTQIMAYFDENLKSNWAGPVHWKIQKVKNLIFVDQKPPEPGTDTVLPKPTEETQDEPTEGIDP
LQLGSEEPVASAAVDGKKKVRRRKDITTIDMLNDQDVLDDDIFISGESRIYIPRNQRNVTTNLLPEDMHFQSDDLIHLFY
KPKATLFRQNSGASKATVQVGPIGDKNVDSEGLPKPNEFIDENFFAGHMNENGQTDIHPNFGDEAFQVFDNAGGDDDDND
YGGDYGGDYGDDDMGGNTFPDSTQVDPYNNSGDGRLGSVGLDEAQIDLLRSLRARPEYVPYARSAKRVDLKRLKDNVWDI
LDLDEANNDGEMEIDGDEGRSPPPEKSPPVHHEERMFSSLMKNLDTIYQGRQLQDISTSFCFISLLHLANEKGLVLESRE
DYTDIAIKRDLSVRKDQLSA

GO term prediction

Biological Process

GO:0007076 mitotic chromosome condensation

Molecular Function

None predicted.

Cellular Component

GO:0000796 condensin complex