Protein

MIA_03076_1

Length
518 amino acids

Browser: contig04:171604-173210+

Protein function

EGGNOG:0PFGRFG01185.1(GTP)-binding protein
SGD closest match:S000000808NUG1Nuclear GTP-binding protein NUG1
CGD closest match:CAL0000184634orf19.2917RNA-binding GTPase

Protein alignments

%idAln lengthE-value
MCA_03108_174.517%5180.0MCA_03108_1
A0A0J9XGZ0_GEOCN60.465%4739.56e-174Similar to Saccharomyces cerevisiae YER006W NUG1 GTPase that associates with nuclear 60S pre-ribosomes OS=Geotrichum candidum GN=BN980_GECA16s01352g PE=4 SV=1
UniRef50_A0A0J9XGZ060.465%4731.96e-170Similar to Saccharomyces cerevisiae YER006W NUG1 GTPase that associates with nuclear 60S pre-ribosomes n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XGZ0_GEOCN
A0A060T7V8_BLAAD58.847%5033.10e-165ARAD1C31020p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C31020g PE=4 SV=1
Q6C0U3_YARLI52.190%5253.38e-156YALI0F21725p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F21725g PE=4 SV=1
A0A167FJD7_9ASCO67.236%3514.13e-149RNA-binding GTPase NUG1 OS=Sugiyamaella lignohabitans GN=NUG1 PE=4 SV=1
NUG1_YEAST47.732%5072.66e-144Nuclear GTP-binding protein NUG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUG1 PE=1 SV=1
A0A1E3PM66_9ASCO59.836%3663.96e-138Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_41158 PE=4 SV=1
A0A1D8PMJ1_CANAL57.423%3571.92e-130RNA-binding GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2917 PE=4 SV=1
A0A1E4TKL6_9ASCO43.495%5158.42e-110Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_42894 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9928
Predicted cleavage: 43

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 518

Detailed signature matches

  1. Domain IPR014813
    Guanine nucleotide-binding protein-like 3, N-terminal domain
    1. PF08701 (GN3L_Grn1)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR030378
    Circularly permuted (CP)-type guanine nucleotide-binding (G) domain
    1. PS51721 (G_CP)
  4. Domain IPR006073
    GTP binding domain
    1. PF01926 (MMR_HSR1)
    2. PR00326 (GTP1OBG)
  5. Domain IPR023179
    GTP-binding protein, orthogonal bundle domain
    1. G3DSA:1.10.15...
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd04178 (Nucleostem...)
  3. mobidb-lite (disord...)

Residue annotation

  1. G4 box cd04178
  2. GTP/Mg2+ binding s...
  3. G5 box cd04178
  4. G1 box cd04178
  5. Switch I region cd...
  6. G2 box cd04178
  7. G3 box cd04178
  8. Switch II region c...

Protein sequence

>MIA_03076_1
MASKVKKSKSKRGTTRLREGIKKKIAAHNRKQRKLSKKDPTWKSRHPRDPGIPSSFPFKDKILEDIEESRRIDAELKAQR
REERRQALVNAGETNPESIEAQLDQEERQDNSTRLAALLESAQAAADEFDSDEEDEDDDEMDTEDVEGVIDIEIEDNDSK
DSSRKAFDKIFKAVVDRSDVILYVLDARDPEGTRSRQVEQAVLAKPDKRLLFVLNKIDLVPSNVLKQWHSALKLSFPTLP
LAADKAASNAVTFVHKGLTQQSTASALLQALKAYAAKSNLKRSITVGVVGYPNVGKSSVINALLSRHGGFKRACPVGAQA
GVTTTIRQVKIDNKLSVLDSPGIVFPAVETAKKGSTPVDEQSRLVLLNALPPKQIDDPVPAVSLLLKRISKNAELRERLM
AIYKLTPLNDSSFNSLVTDFLVQIARKKGRLGKGGIPDLKGAAHAVIVDWRDGRIPGWTLPDASALEPQIPETKSDLVIA
PSGAKEEKVIVTEWAQEFSLDGLWDGNFGGDEDDVEMS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005525 GTP binding

Cellular Component

None predicted.