Protein

MIA_03066_1

Length
929 amino acids

Browser: contig04:146366-149156-

Protein function

EGGNOG:0PF9EFG00824.1complex, subunit alpha
SGD closest match:S000000133APL3AP-2 complex subunit alpha
CGD closest match:CAL0000177244orf19.2786Uncharacterized protein

Protein alignments

%idAln lengthE-value
MCA_01594_170.930%9460.0MCA_01594_1
A0A0J9X6N6_GEOCN67.094%9360.0Similar to Saccharomyces cerevisiae YBL037W APL3 Alpha-adaptin OS=Geotrichum candidum GN=BN980_GECA04s00186g PE=4 SV=1
A0A060TA02_BLAAD58.668%9460.0ARAD1C40920p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C40920g PE=4 SV=1
A0A167EQ74_9ASCO58.664%9580.0Apl3p OS=Sugiyamaella lignohabitans GN=APL3 PE=4 SV=1
UniRef50_A0A0G4KXM650.321%9340.0Uncharacterized protein n=1 Tax=Verticillium longisporum TaxID=100787 RepID=A0A0G4KXM6_9PEZI
A0A1E3PFK8_9ASCO47.928%9410.0Adaptor protein-like protein complex AP-2 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_36740 PE=4 SV=1
Q6CBH9_YARLI47.689%9520.0YALI0C18623p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C18623g PE=4 SV=1
A0A1E4TJV1_9ASCO39.373%8610.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_609 PE=4 SV=1
A0A1D8PE70_CANAL31.679%10481.50e-111Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2786 PE=4 SV=1
AP2A_YEAST26.976%10122.78e-83AP-2 complex subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APL3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6544
Predicted cleavage: 20

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 929

Detailed signature matches

  1. Family IPR017104
    Adaptor protein complex AP-2, alpha subunit
    1. PIRSF037091 (AP2_alpha)
  2. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  3. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
  4. Domain IPR002553
    Clathrin/coatomer adaptor, adaptin-like, N-terminal
    1. PF01602 (Adaptin_N)
  5. Domain IPR013041
    Coatomer/clathrin adaptor appendage, Ig-like subdomain
    1. SSF49348 (Clathrin ...)
  6. Domain IPR008152
    Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
    1. PF02883 (Alpha_adap...)
    2. SM00809 (alpha_adap...)
  7. Domain IPR003164
    Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain
    1. PF02296 (Alpha_adap...)
  8. Domain IPR009028
    Coatomer/calthrin adaptor appendage, C-terminal subdomain
    1. SSF55711 (Subdomain...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:2.60.40...
  3. G3DSA:3.30.31...

Protein sequence

>MIA_03066_1
MSQPMKGLVRFIADLRNAREREVEAKRINQELANIRNKFKDSSLNGYQKKKYICKLIYIYILGYEVNFGHLESISLISSS
TYSEKQIGYLAVSVLLNENSDMLHLVINSIKKDLSSMNEYFTCLALNCIATVGGSTISDALADDIFKLLISPTSQDFVRK
KAALTILRLYRRDKKIIPPSRADRIIAQIDSDNLGVATSIASLVSEMVQENPDANKLVYSKVVRRLQHLVFENGCPEEYY
YYTVPAPWFFVKLLRLLQFFPPSNDETIKLSIRKVITQIISSNSIPSKNIQQSNAQNAVLFEAIDLAIHLDMDHNLMEQI
VQILGQFLTSKETNTRYLAIGALANMASRYEQVPISSHLITITQSLRDRDISVRRKAIDLLYSICNASNVRTIVNELLKY
LQAADFSIRGEMVIRIAVLVEKYATEYQWYVDISLRLLSIAGPHVNDEVWQRVVQIVVNNENLQEYSVKTIFQYLKSPNC
NENLIKVGGYLLGEYGNLISTQQGSGPLDQFLALHDKFPSCSSFTKGLLLTTYIKFVNLFPEIKPQLVQVFEYNSKSIDS
ELQQRSYEYLKMSSAEHIKLLPIIWDEMPPFPERSSTMLTRIKTKRITNTEGKRLWAPGSRRQKELQAAAATSATATAAV
ASTNTQNLLFENTPAPATSSIPVLTPSVATPTQPTAAPAEELLTSGWEQNFKKLILNAEGIFYEDSMLQIGLRSDYRRHL
GCVILYFRNNSGSTLQSLSVEITNHENPKLTVTTKNFPDSSIAANKTTQQVIMLEAHEPFQEAPTVKITYLAGTLQVLTL
KLPVVLEKFMLPTELSTEDYFKRWAQIGATGGTGLEAQLVFKNRAFGSGINDGRIMAALQWSRIENADRNPRNIVGAGII
HTSNGGSFGCLVRLEPNEDQSMYRVTVRATDARIPAILAKNISSMYQLL

GO term prediction

Biological Process

GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport

Molecular Function

GO:0005488 binding
GO:0008565 protein transporter activity

Cellular Component

GO:0016020 membrane
GO:0030117 membrane coat
GO:0030131 clathrin adaptor complex