Protein

MIA_03058_1

Length
962 amino acids


Browser: contig04:129889-132778-

Protein function

EGGNOG:0PGAXFGSG_11966ubiquitin conjugation factor E4
SGD closest match:S000002349UFD2E4 ubiquitin-protein ligase UFD2
CGD closest match:CAL0000195094orf19.5965Ubiquitin-ubiquitin ligase

Protein alignments

%idAln lengthE-value
MCA_03006_148.914%9670.0MCA_03006_1
A0A0J9XC65_GEOCN46.764%9580.0Similar to Saccharomyces cerevisiae YDL190C UFD2 Ubiquitin chain assembly factor (E4) that cooperates with a ubiquitin-activating enzyme (E1) OS=Geotrichum candidum GN=BN980_GECA09s04531g PE=4 SV=1
UniRef50_A0A0J9XC6546.764%9580.0Similar to Saccharomyces cerevisiae YDL190C UFD2 Ubiquitin chain assembly factor (E4) that cooperates with a ubiquitin-activating enzyme (E1) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XC65_GEOCN
A0A167DBZ2_9ASCO40.469%9810.0Ubiquitin-ubiquitin ligase UFD2 OS=Sugiyamaella lignohabitans GN=UFD2 PE=4 SV=1
A0A060T298_BLAAD41.834%9490.0ARAD1C29590p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C29590g PE=4 SV=1
A0A1E3PLB3_9ASCO40.574%9760.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46380 PE=4 SV=1
Q6C9B7_YARLI37.447%9400.0YALI0D12452p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D12452g PE=4 SV=1
A0A1E4TFY9_9ASCO37.778%9450.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2415 PE=4 SV=1
UFD2_YEAST37.317%8871.27e-178E4 ubiquitin-protein ligase UFD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UFD2 PE=1 SV=3
Q5AND8_CANAL39.437%7811.19e-176Ubiquitin-ubiquitin ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5965 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4111

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 962

Detailed signature matches

    1. PF10408 (Ufd2P_core)
    1. PS51698 (U_BOX)
    2. PF04564 (U-box)
    3. SM00504 (Ubox_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF57850 (RING/U-box)
  2. cd16657 (RING-Ubox_...)

Protein sequence

>MIA_03058_1
MATAQTAESTALEKALNLSLTPITAEGSKGVNKVPLYLADFAAELNQEERPLLFSIEDIDAILWAAIHQKFHTQKLAYFY
FYRSWKHSEDMLRSLSKSHSDTANAQTSTLRQLQAFLINYGLLAATEPDVFEPEEGNKPFDLSYFITKQNDDSERFWSFF
HLIANRAAENATLPEFIEPIVQHINSKISSSPMLNPSTSSSYLEAFEHLVTNKNILTCIVDLESFNPKGLSAPELEKKSV
LGPILGISPVNPQSSMATFGKSSTLTEAAIQNSYLSIRSELKFIQEKHFYLCDKIIRNSEHTRNKLLEFFGSLIDANHKR
LAMQVDHKTISSDAIMINVTALLIRFCDPFLDVHGSKIDKISMEYFSIKPVFSIDDETMINSDSAEAKAYYEKTKDSSKK
VNFISDVFYLTIAFLHYGVGGCLHYHERTRKHLEDMQNHEQYLRKQLEQYKGTPNERALRMALAKLEGEKDIINAYFHII
KAVLFDHNLQSQIMKFDLFLSVFLVRAVDPNKKYPSQKITLPFPSDQPPNNFKYLPEYFLDTIPTSVLFLSRNLPDILIH
QNLAPLLTFLVTFLRMTHYVKNPYVKTKFVEVIFTGTIELFVNKRGFFVDSFNTDSMCLDNLFHTLLQFYIDIERTGASS
QFEDKFNARYYISQIIKTLWNNRVYRDRLESESKTDTEFFVRFVALLLNDATYLLDESLSKLAEIHRLQKELESSDPAHI
SAEQTELQRQLVSVERMAKSYVQLAQQSVILLKLFTQTVPKAFVTPELVDRLAAMLDYNLEALVGPKCRELKVKNSEEYG
FKPRELLSYLVDVYLNLSKQEEFVKAVANDGRSFRPELFERAVDLLSKRLLKSPAEISQLKKFAADAVRIKDETEADEEE
LGEIPDEFMDPIMYTLMRDPVILPASRTTVDLATIKSHLLSDSSDPFNRSPLTIDQVVPNTELKKRIEEFKQSRKRAKFE
HS

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016567 protein ubiquitination

Molecular Function

GO:0004842 ubiquitin-protein transferase activity
GO:0034450 ubiquitin-ubiquitin ligase activity

Cellular Component

GO:0000151 ubiquitin ligase complex