Protein

MIA_03025_1

Length
452 amino acids

Browser: contig04:46883-48242-

Protein function

EGGNOG:0PFMGPGUG_00188Kynurenine aminotransferase
SGD closest match:S000003596BNA3Probable kynurenine--oxoglutarate transaminase BNA3
CGD closest match:CAL0000179444orf19.5809Kynurenine--oxoglutarate transaminase

Protein alignments

%idAln lengthE-value
MCA_03861_178.372%4300.0MCA_03861_1
A0A167DJR6_9ASCO70.861%4530.0Bna3p OS=Sugiyamaella lignohabitans GN=BNA3 PE=4 SV=1
A0A0J9X3I7_GEOCN74.528%4240.0Similar to Saccharomyces cerevisiae YJL060W BNA3 Kynurenine aminotransferase OS=Geotrichum candidum GN=BN980_GECA01s03717g PE=4 SV=1
A0A060SWD0_BLAAD70.709%4370.0ARAD1A03278p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A03278g PE=4 SV=1
Q6C490_YARLI67.184%4510.0YALI0E28787p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E28787g PE=4 SV=1
A0A1E3PUS4_9ASCO64.846%4210.0PLP-dependent transferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81501 PE=4 SV=1
UniRef50_A0A0P7BRE460.859%4190.0Putative aminotransferase C6B12.04c n=2 Tax=Hypocreales TaxID=5125 RepID=A0A0P7BRE4_9HYPO
BNA3_YEAST54.893%4191.51e-165Probable kynurenine--oxoglutarate transaminase BNA3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BNA3 PE=1 SV=1
A0A1D8PGR0_CANAL54.458%4157.35e-158Kynurenine--oxoglutarate transaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5809 PE=4 SV=1
A0A1E4TE97_9ASCO71.863%2631.14e-145Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31087 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9959
Predicted cleavage: 21

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 452

Detailed signature matches

  1. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  2. Domain IPR004839
    Aminotransferase, class I/classII
    1. PF00155 (Aminotran_1_2)
  3. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...
  4. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...
  5. SITE IPR004838
    Aminotransferases, class-I, pyridoxal-phosphate-binding site
    1. PS00105 (AA_TRANSFE...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00609 (AAT_like)

Residue annotation

  1. pyridoxal 5'-phosp...
  2. homodimer interfac...
  3. catalytic residue ...

Protein sequence

>MIA_03025_1
MFFRRTLSLNLSLKRAPFRLMSSSAPFKPFPTPSAKVSNSAKDVWSLINETAAAVERDSGEKVVNLGQGFFSYSPPDFAI
QAAKESLDVAALNQYAPTRGLLNLRKAIADAYTPYFDRKLDPETEIVVTAGANEGMFAAFTGFLNQDDEVIVFEPFFDQY
ISNIQLPGGVVKYVPLHPPVDGDSRIASASEWSIDFDELEKTITPRTKMIVINSPQNPTGKVFSRDELLKIGELAVKYNF
IILSDEVYDRLYYTEFVRIATLSPAISRLTLTVGSAGKTFSATGWRVGWLIGHPELIKYVAAAHTRITFTVNTPLSNAVA
KALEAAQTNGYYEGQVDSFRKKYAILTGVFDEIGLPYTVAEGGYFLLVNFAKVKVPEDYVFPEDVTVGRAKDFRIAYWLI
KEFGVVAIPPTEFYTVENAHLAEDYLRFAVCKDDWMLEAAVEKLRGLKKYIA

GO term prediction

Biological Process

GO:0009058 biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.