Protein

MIA_02969_1

Length
526 amino acids

Browser: contig03:2217716-2219297-

Protein function

EGGNOG:0PJ3BPGUG_05594Cytochrome b2
SGD closest match:S000004518CYB2Cytochrome b2, mitochondrial
CGD closest match:CAL0000184748CYB2Cyb2p

Protein alignments

%idAln lengthE-value
MCA_03469_168.63%5260.0MCA_03469_1
A0A060T3D8_BLAAD65.51%5190.0ARAD1C32274p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32274g PE=3 SV=1
UniRef50_A0A060T3D865.51%5190.0ARAD1C32274p n=15 Tax=Fungi TaxID=4751 RepID=A0A060T3D8_BLAAD
A0A0J9XHX1_GEOCN62.99%5350.0Similar to Saccharomyces cerevisiae YML054C CYB2 Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) OS=Geotrichum candidum GN=BN980_GECA18s01000g PE=3 SV=1
A0A1E3PMN3_9ASCO63.38%5270.0FMN-dependent dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50476 PE=3 SV=1
Q6C538_YARLI62.40%5240.0YALI0E21307p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E21307g PE=3 SV=1
A0A1E4TJ84_9ASCO56.68%5240.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_75807 PE=3 SV=1
A0A167D3H0_9ASCO68.59%3820.0Cyb2p OS=Sugiyamaella lignohabitans GN=CYB2 PE=3 SV=1
Q5AKX8_CANAL65.93%4080.0Cyb2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CYB2 PE=3 SV=1
CYB2_YEAST48.28%5225e-171Cytochrome b2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CYB2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0197

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 526

Detailed signature matches

  1. Family IPR012133
    Alpha-hydroxy acid dehydrogenase, FMN-dependent
    1. PS51349 (FMN_HYDROX...)
  2. Domain IPR001199
    Cytochrome b5-like heme/steroid binding domain
    1. SSF55856 (Cytochrom...)
    2. PS50255 (CYTOCHROME...)
    3. PR00363 (CYTOCHROMEB5)
    4. PF00173 (Cyt-b5)
    5. G3DSA:3.10.12...
    6. SM01117 (Cyt_b5_2)
  3. Domain IPR013785
    Aldolase-type TIM barrel
    1. G3DSA:3.20.20.70
  4. Domain IPR000262
    FMN-dependent dehydrogenase
    1. PF01070 (FMN_dh)
  5. SITE IPR018506
    Cytochrome b5, heme-binding site
    1. PS00191 (CYTOCHROME...)
  6. SITE IPR008259
    FMN-dependent alpha-hydroxy acid dehydrogenase, active site
    1. PS00557 (FMN_HYDROX...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. SSF51395 (FMN-linke...)
  3. cd02922 (FCB2_FMN)
  4. mobidb-lite (disord...)

Residue annotation

  1. homodimer interfac...
  2. substrate binding ...
  3. active site cd02922
  4. FMN binding site c...
  5. catalytic residues...

Protein sequence

>MIA_02969_1
MPSYEEVAKHNSPESVWIIVHGKVYDVTAFLPEHPGGQKIILRYAGKDATAKFDTIHPKDIIDKLLPKEAYLGPVTGTPP
SSSQKSEKKSKEAQQEEEDDEEEDEDDEDSEYETIRSKYNENKPPLNQMYNLFDFENVARRVMTRTGWGYYSSGADDEIT
LRENHRAFHRIWFRPRVLVDVTHVDPSTSLLGIKSSLPIYITATALGRLGHPDGEKVLTRAAAHENVIQMIPTLASCSFD
EIVNARLKPDQPQWFQLYVNMDREITKKIVQHAEKRGIKGLFITVDAPQLGRREKDMRAKYVAQGANVQEEDEEEEEDDQ
EVSGSGIDRSQGYARAISSFIDPALSWKDLVWFRSITKMPILIKGVGRVEDAIRAAEAGIDGIVISNHGGRQLEFAKPAI
EVLAEVMPALRARGLDKNFEVYIDGGIRRATDIVKAVCLGAKGVGIGRPFLYAMSSYGEKGVRRAIQLLRDEFEMNMRLL
GVTSVDQLNETFLDIRDLSHHSAIPSDNLTQAVYEPMTPPTFKSKI

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0020037 heme binding

Cellular Component

None predicted.