Protein

MIA_02899_1

Length
268 amino acids


Browser: contig03:2050142-2050949-

Protein function

EGGNOG:0PGKSPRE4The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity)
SGD closest match:S000001946PRE4Proteasome subunit beta type-7
CGD closest match:CAL0000179123orf19.4230Proteasome subunit beta

Protein alignments

%idAln lengthE-value
MCA_02645_169.888%2693.97e-134MCA_02645_1
A0A1E3PEL6_9ASCO70.455%2644.89e-128Proteasome subunit beta OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84475 PE=3 SV=1
A0A0J9XHV5_GEOCN69.888%2695.25e-128Proteasome subunit beta OS=Geotrichum candidum GN=BN980_GECA18s00780g PE=3 SV=1
A0A060T507_BLAAD60.584%2745.51e-113Proteasome subunit beta OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C07678g PE=3 SV=1
UniRef50_A0A1W5CRL259.701%2682.52e-9820s proteasome subunit beta 7 n=1 Tax=Umbilicaria pustulata TaxID=136370 RepID=A0A1W5CRL2_9LECA
Q6C3S4_YARLI60.377%2651.01e-99Proteasome subunit beta OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E32505g PE=3 SV=1
A0A1E4TK31_9ASCO54.789%2611.91e-92Proteasome subunit beta OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_82607 PE=3 SV=1
A0A1D8PNC8_CANAL52.330%2794.48e-90Proteasome subunit beta OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4230 PE=3 SV=1
PSB7_YEAST55.351%2712.63e-89Proteasome subunit beta type-7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRE4 PE=1 SV=1
A0A167D7T9_9ASCO67.969%1282.79e-57Proteasome core particle subunit beta 7 OS=Sugiyamaella lignohabitans GN=PRE4 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0675

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 268

Detailed signature matches

    1. PF00227 (Proteasome)
    1. PS51476 (PROTEASOME...)
    1. cd03760 (proteasome...)
    1. SSF56235 (N-termina...)
    1. PS00854 (PROTEASOME...)

Residue annotation

  1. active site cd03760
  2. beta subunit inter...

Protein sequence

>MIA_02899_1
MDHFQTNWGRPRDDIYGSYDKRIHEASDAAAAANIPTTNTQAPIVTGTSVIAIKFNKGVIIAADNLASYGSLARFTDVER
LLPVGRDTVVGVGGDISDYQYLQRMLEQLEINDNYDNDGFELTASNIFHYISNVMYNRRSRMNPLWNAIVVAGVDPATKE
PFLSTVDLRGVTYSAPTLATGFGAYLAVPLLRQLVDDEKDVAKVTEEEARKMIDTCMKVLFYRDARSLDKYSVATITAEG
VKFDKNVRPENMNWNFAGGIKGYGTQDE

GO term prediction

Biological Process

GO:0051603 proteolysis involved in cellular protein catabolic process

Molecular Function

GO:0004175 endopeptidase activity
GO:0004298 threonine-type endopeptidase activity

Cellular Component

GO:0005839 proteasome core complex