Protein

MIA_02893_1

Length
472 amino acids

Browser: contig03:2032437-2033856+

Protein function

EGGNOG:0PFS6TIM44inner membrane translocase subunit tim44
SGD closest match:S000001284TIM44Mitochondrial import inner membrane translocase subunit TIM44
CGD closest match:CAL0000195007TIM44Mitochondrial import inner membrane translocase subunit TIM44

Protein alignments

%idAln lengthE-value
MCA_03125_184.289%4010.0MCA_03125_1
A0A0J9X3H2_GEOCN74.372%3980.0Mitochondrial import inner membrane translocase subunit TIM44 OS=Geotrichum candidum GN=BN980_GECA01s09910g PE=3 SV=1
A0A167EIG8_9ASCO66.416%3991.35e-169Mitochondrial import inner membrane translocase subunit TIM44 OS=Sugiyamaella lignohabitans GN=TIM44 PE=3 SV=1
A0A060SZU7_BLAAD63.476%3978.05e-167Mitochondrial import inner membrane translocase subunit TIM44 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06798g PE=3 SV=1
A0A1E3PK99_9ASCO67.172%3964.34e-165Mitochondrial import inner membrane translocase subunit TIM44 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83371 PE=3 SV=1
A0A1E4TME8_9ASCO57.250%4001.79e-141Mitochondrial import inner membrane translocase subunit TIM44 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56388 PE=3 SV=1
Q6C8B1_YARLI55.779%3985.79e-136Mitochondrial import inner membrane translocase subunit TIM44 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D21142g PE=3 SV=1
UniRef50_Q6C8B155.779%3981.34e-132Mitochondrial import inner membrane translocase subunit TIM44 n=3 Tax=Saccharomycetales TaxID=4892 RepID=Q6C8B1_YARLI
Q5A7M2_CANAL50.000%3982.69e-116Mitochondrial import inner membrane translocase subunit TIM44 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TIM44 PE=3 SV=1
TIM44_YEAST46.734%3983.31e-107Mitochondrial import inner membrane translocase subunit TIM44 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TIM44 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9945
Predicted cleavage: 47

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 472

Detailed signature matches

  1. Family IPR017303
    Mitochondrial import inner membrane translocase subunit Tim44
    1. PIRSF037871 (TIM44)
  2. Domain IPR032710
    NTF2-like domain
    1. SSF54427 (NTF2-like)
  3. Domain IPR007379
    Tim44-like domain
    1. SM00978 (Tim44_a_2)
    2. PF04280 (Tim44)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. mobidb-lite (disord...)

Protein sequence

>MIA_02893_1
MLRLSNMSRSRGMAMAVRSLASSRQALAYPALTGARTFSQSSVQRSSAEDQKKQDDQKQEQQKKSSPSDDDANIDKTPLQ
VFFDTFKREWQKSEELQSNIKALQDETGRMAESAAYKKAKEALEKAQEGTSSATSATSATIKKASKVVGQVAHEAWESPV
IKTTRVVASKTADAVEKATEPIRETQAYKTVKDVIDDGSSMRYGGYEDKQTRRLRRQQEAQKELEEELRTGKKKSKPVKE
DIMAGQAVVLHENPEPVETWRDSWAKWKAESAAGKRLSDLQTAYEETDNGFISTIRTIGDKIGGFFEETENARVIRMFKE
LDPEFNQEKFLKEVRGYIIPEVLDAYVKGDEETLKLWLSEAPFNIWAASTKQYKEAGLYSASRVLDIRGVDILQAKLLPP
QDVPVFVIGCRAQEVHMYKNIKTDEIAAGMEDHIQQSTYAMVITRIPENIEDPETKGWQILELVRGQTRDWT

GO term prediction

Biological Process

GO:0030150 protein import into mitochondrial matrix

Molecular Function

GO:0051087 chaperone binding

Cellular Component

None predicted.