Protein

MIA_02754_1

Length
664 amino acids

Browser: contig03:1654966-1656961-

Protein function

EGGNOG:0PIH6PGUG_05127asparagine
SGD closest match:S000004562YML096WAsparagine synthetase domain-containing protein YML096W
CGD closest match:CAL0000180997orf19.3626Putative asparagine synthase

Protein alignments

%idAln lengthE-value
MCA_05564_141.971%6298.98e-147MCA_05564_1
A0A0J9XCN7_GEOCN38.109%6776.10e-124Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA10s02188g PE=4 SV=1
UniRef50_A0A0J9XCN738.109%6771.25e-120Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCN7_GEOCN
A0A167D7N8_9ASCO37.086%6046.76e-101Putative asparagine synthase OS=Sugiyamaella lignohabitans GN=AWJ20_839 PE=4 SV=1
A0A060SZG3_BLAAD38.422%5831.02e-99ARAD1C07524p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C07524g PE=4 SV=1
A0A1E3PMR9_9ASCO34.697%6111.23e-95Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_73878 PE=4 SV=1
Q6C033_YARLI34.768%5813.28e-84YALI0F28149p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F28149g PE=4 SV=1
A0A1D8PIA3_CANAL36.339%3665.12e-64Putative asparagine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3626 PE=4 SV=1
A0A1E4TAG3_9ASCO44.586%3147.37e-64Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3385 PE=4 SV=1
ASND1_YEAST39.683%3151.87e-53Asparagine synthetase domain-containing protein YML096W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YML096W PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3308
Predicted cleavage: 11

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 664

Detailed signature matches

  1. Domain IPR029055
    Nucleophile aminohydrolases, N-terminal
    1. G3DSA:3.60.20.10
    2. SSF56235 (N-termina...)
  2. Domain IPR017932
    Glutamine amidotransferase type 2 domain
    1. PF13537 (GATase_7)
  3. Domain IPR014729
    Rossmann-like alpha/beta/alpha sandwich fold
    1. G3DSA:3.40.50...
  4. Domain IPR001962
    Asparagine synthase
    1. PF00733 (Asn_synthase)
    2. cd01991 (Asn_Syntha...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. SSF52402 (Adenine n...)
  3. mobidb-lite (disord...)

Residue annotation

  1. Molecular Tunnel c...
  2. Ligand Binding Sit...

Protein sequence

>MIA_02754_1
MCGILAFLRPVAVSKYPSPSYLDNVYPRLRKETAARGPDALSSPIDPAPDPDCRQTTPPLTGVPPDPEYPCGGASSLRVF
SSVLSLRPPLTPQPIVVPDQSGRPQLVVQFNGELYNDDISGNDTAYFASAVAQALLHPDRPSDSDGGKAARARQMRKVVQ
QLRGEYAFVVTDCVHGECWFARDPIGRRSLVKIQSCGADAKKEEGDSGVIFCSVAAVSISGNKEDLGIDETRIRVEEVPA
GVLSCLETDSHQLSSYNWTYADSTQGPQEAATLAYPYTRVNQALLPAAPTAEEEAARLTQQLDELLEQATRRRVADIPYI
VHRPSSLDELDSCGASSPSSSASALPPLPAQRPRVAVLFSGGLDCSLVAQYVARIVAETHPNEPIDLLNVAFENPRVAAA
HSATQKAPKKKNKPGAQDVHPASFDIYDTPDRVLARKSWKALASKYPALRLVEINVPYSATLTHRARVQRLMYPQATAMD
LSIAIAFYFAARGHGTLYRAPAAPPVPAYTTSASVLFSGLGADELFGGYMRHARVLEEGDGRPARDRYRQLAGELQLDFS
RLDSRNLGRDDRVCSAWAREVRYVFLDEAVVRWATARCPLDLKVGRPREGAKEPETKVVLRRVARLMGEAMAASAEEKKR
AVQFGSRSAKMEVGSGRSKGTDAL

GO term prediction

Biological Process

GO:0006529 asparagine biosynthetic process

Molecular Function

GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity

Cellular Component

None predicted.