Protein

MIA_02748_1

Length
927 amino acids

Browser: contig03:1639406-1642190+

Protein function

EGGNOG:0PH0BPGUG_04395C6 zinc finger
SGD closest match:S000002621UPC2Sterol uptake control protein 2
CGD closest match:CAL0000191743UPC2Sterol uptake control protein 2

Protein alignments

%idAln lengthE-value
MCA_03173_179.787%3760.0MCA_03173_1
A0A0J9XDV6_GEOCN69.841%3784.43e-176Similar to Saccharomyces cerevisiae YDR213W UPC2 Sterol regulatory element binding protein OS=Geotrichum candidum GN=BN980_GECA11s01462g PE=4 SV=1
UniRef50_A0A0J9XDV669.841%3789.06e-173Similar to Saccharomyces cerevisiae YDR213W UPC2 Sterol regulatory element binding protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDV6_GEOCN
A0A060T2I3_BLAAD59.341%3649.15e-130ARAD1C32296p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32296g PE=4 SV=1
Q6CEG5_YARLI51.187%3793.18e-115YALI0B15818p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15818g PE=4 SV=1
A0A1E3PQL1_9ASCO44.030%4029.50e-97Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53879 PE=4 SV=1
UPC2_CANAL53.947%3043.41e-89Sterol uptake control protein 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=UPC2 PE=1 SV=1
UPC2_YEAST50.323%3105.74e-83Sterol uptake control protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UPC2 PE=1 SV=1
A0A167DWS6_9ASCO63.203%2311.39e-79Upc2p OS=Sugiyamaella lignohabitans GN=UPC2 PE=4 SV=1
A0A1E4TE67_9ASCO44.681%475.52e-09Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1799 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6323
Predicted cleavage: 44

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 927

Detailed signature matches

  1. Family IPR021858
    Fungal transcription factor
    1. PF11951 (Fungal_tra...)
  2. Domain IPR001138
    Zn(2)-C6 fungal-type DNA-binding domain
    1. PF00172 (Zn_clus)
    2. G3DSA:4.10.24...
    3. PS00463 (ZN2_CY6_FU...)
    4. SM00066 (gal4_2)
    5. SSF57701 (Zn2/Cys6 ...)
    6. PS50048 (ZN2_CY6_FU...)
    7. cd00067 (GAL4)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.11...
  2. mobidb-lite (disord...)

Residue annotation

  1. DNA binding site c...
  2. Zn2+ binding site ...

Protein sequence

>MIA_02748_1
MSTLIAQPTTRPSRRSSKLQQQQQQPLNNHYHHHNQQQHNARTTPLSPLCTTTPAGFNNLPSPIAIKQEPLLYSPQEQQI
NNIHSQQHSHLFSNACSSPTTTSSILSSNDFSPLMAQSPGFSAGITAGFKSVSANTSPPTPNSCTGFSPDDFATSLSVQV
CGMAQQQQNLQPKQKQPSSNQTTRRVSACAGSRPRRSCVASTSSSTPTNCCSSSPSFTCTTTKNSKVSSATPSTTSTPSS
TPSTTTTGKRKSGSPAMDPVTGKPKTTKRRPHSKSRHGCKTCKRRRVKCDETHPICNNCKHLNLECSFAGNSLFPFVQGG
LNIMDIRLFHHYTTVVWKTIVSAGISNETIWAQDVPQLAFEHPYLMHSVLTFAANHFSRSHQGADHDPATLEQVVTFHRG
DALRLLGEAVRSVTPENLDALVASSILLILDSLANASPSDDQSASSLPASAWLHHVRGAATILTAIGPPSTDSRFFNLVN
VDLSDLAQGLMTSIPGIDVVAALECFDEDLRDLYPVNVSSPYYHALVYLDKLFRQRYKSDFILRVFSFPALLDRNLVTML
INGDESAKKIIRVYYKLVRSFTSEMHQSVWFLEGVSKVLPIDMDKEFGGLGFITQALPLKLPTVDEFIESFFKTPSQQQP
QQERQQRLQQSSIQSPAMTAANAVRNTRRTKTNNAATKSHLQHGTSSTPILISDSPASQTTTDLRTVTGTHEDLDPTQFS
LDLLSNDASAAASELESFASQFMLQATTGPVNHGTATTGPSSTSSIQLPSQPLCASGIMSSQGQSNQDLLVGPHSSPTMS
SSSPLSLDNDYGLPTGPDTSGSSNNSTSSNEPHSRHGTPVFPPMNTATTNFGTLPHKLTTLMTPHDDTMNSFKFNEHHLH
SSFDKNPNARVAAGASPAELSLDGCTTITPSMLTVDEANFLIKYEKS

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0008270 zinc ion binding

Cellular Component

GO:0005634 nucleus