Protein

MIA_02731_1

Length
584 amino acids

Browser: contig03:1580074-1581996+

Protein function

EGGNOG:0PIFZPGUG_01169eukaryotic translation initiation factor
SGD closest match:S000003286YGR054WEukaryotic translation initiation factor 2A
CGD closest match:CAL0000199029orf19.2930Eukaryotic translation initiation factor 2A

Protein alignments

%idAln lengthE-value
MCA_01382_162.175%6160.0MCA_01382_1
A0A0J9XD93_GEOCN60.374%5880.0Eukaryotic translation initiation factor 2A OS=Geotrichum candidum GN=BN980_GECA10s01968g PE=3 SV=1
UniRef50_A0A0J9XD9360.374%5880.0Eukaryotic translation initiation factor 2A n=3 Tax=Ascomycota TaxID=4890 RepID=A0A0J9XD93_GEOCN
A0A060TBG9_BLAAD54.950%6060.0Eukaryotic translation initiation factor 2A OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B07568g PE=3 SV=1
A0A1E3PPN8_9ASCO51.356%6270.0Eukaryotic translation initiation factor 2A OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82518 PE=3 SV=1
Q6CCJ4_YARLI50.260%5770.0Eukaryotic translation initiation factor 2A OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C08877g PE=3 SV=1
A0A1D8PCQ3_CANAL44.168%6431.85e-174Eukaryotic translation initiation factor 2A OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2930 PE=3 SV=1
A0A1E4TK86_9ASCO42.718%6181.26e-166Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_758 PE=3 SV=1
A0A161HJ73_9ASCO70.833%3363.84e-165Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_4207 PE=4 SV=1
EIF2A_YEAST35.185%6488.76e-117Eukaryotic translation initiation factor 2A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YGR054W PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1379

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 584

Detailed signature matches

  1. Family IPR011387
    Translation initiation factor 2A
    1. PIRSF017222 (Transl...)
  2. Domain IPR015943
    WD40/YVTN repeat-like-containing domain
    1. G3DSA:2.130.1...
  3. Domain IPR013979
    Translation initiation factor, beta propellor-like domain
    1. PF08662 (eIF2A)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF82171 (DPP6 N-te...)
  2. mobidb-lite (disord...)

Protein sequence

>MIA_02731_1
MSQPTTQYFARIPKTVGLYTGTPNYTSFSGFAAPTEAVRQSQYSPNGKYFAYNTANGLFIIDPNSGSILKTIAVENTIEF
AFSPLGSIIMTYERPKRDESCGGDFGPNVKLFKTETGEFICEFAFRSQYNWQLQFTHDEKYCARMVTNQIEFYDSKNFTK
PWARLRAENCSNFSVSPGQNYSVAVFTPEKSGKPASVRVYQLPNFEQPVSQKTFFKAESAKMKWNRLGTALLVLGSTDVD
KTGKSYYGETNLYLLGIAGSYDSRIHLDKEGTIHDFAWSPNSREFGVVYGFMPTTTTIFDARGNVVHTFPIAPRNAIFFS
PHARFILIAGFGNLQGDIDIYDRQKQFSKICTVEASNTSVCEWSPDGRYILTATTSPRLRVDNGIKIWHYTGKLIYSQDY
PELFATSWRPMDANIFPMRSSLSPAPAPHASVAVASGNGSTSSANPTPKGAYVPPHARNKIGASGHVAPTTLYELEQSNN
NAQRQIPGSAGRTVPGAPVKTGKKKNGANKSNEEPLPSISFNPPASAEEKRIRSLLKKIRAIDELKLKRAKGEKLEDTQV
KKIATEKDILEELKSLGWSEENRS

GO term prediction

Biological Process

GO:0006413 translational initiation

Molecular Function

GO:0003743 translation initiation factor activity
GO:0005515 protein binding

Cellular Component

None predicted.