Protein

MIA_02575_1

Length
826 amino acids


Browser: contig03:1167633-1170114+

Protein function

EGGNOG:0PJUBPGUG_01995ubiquitin carboxyl-terminal hydrolase
SGD closest match:S000002280UBP1Ubiquitin carboxyl-terminal hydrolase 1
CGD closest match:CAL0000188694UBP1Ubiquitin-specific protease

Protein alignments

%idAln lengthE-value
MCA_03885_163.830%3766.33e-146MCA_03885_1
A0A0J9X372_GEOCN47.632%3591.72e-101Similar to Saccharomyces cerevisiae YDL122W UBP1 Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins OS=Geotrichum candidum GN=BN980_GECA01s01572g PE=3 SV=1
UniRef50_A0A0J9X37247.632%3593.51e-98Similar to Saccharomyces cerevisiae YDL122W UBP1 Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X372_GEOCN
A0A060T1N5_BLAAD41.361%3822.53e-80ARAD1A01650p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A01650g PE=3 SV=1
A0A167EEG4_9ASCO42.902%3175.04e-67Ubp1p OS=Sugiyamaella lignohabitans GN=UBP1 PE=3 SV=1
UBP1_YEAST34.821%3361.77e-39Ubiquitin carboxyl-terminal hydrolase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBP1 PE=1 SV=2
A0A1D8PKC4_CANAL31.265%4194.41e-38Ubiquitin-specific protease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=UBP1 PE=3 SV=1
Q6CD92_YARLI34.643%2801.13e-34YALI0C02717p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C02717g PE=3 SV=1
A0A1E3PKJ4_9ASCO31.399%2931.20e-23Cysteine proteinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_70196 PE=3 SV=1
A0A1E4TAT8_9ASCO21.505%3724.27e-06Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32326 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1805

Protein family membership

None predicted.

Domains and repeats

1 100 200 300 400 500 600 700 826

Detailed signature matches

    1. PS50235 (USP_3)
    1. PF00443 (UCH)
    1. PS00972 (USP_1)
    2. PS00973 (USP_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF54001 (Cysteine ...)
  2. cd02662 (Peptidase_...)
  3. mobidb-lite (disord...)

Residue annotation

  1. Active Site cd02662

Protein sequence

>MIA_02575_1
MVSDTISGTVDVASASARQIYDLASEKASTAIEGVSDMISGIKRLKDDDLLDSENLIDLNAESFEDEDDDDDETEDSEED
EEDQEDEAKEEEDDDDDDDDDDDDDDEKEEEKKESHQKELKKSNGVIETEEDQGEEKIGKSKNEDVPIAQITTHHELNGQ
SLTPLDKELANDQSLSKLANGSIEHVAKFSAVESPAEPASQATTEPPTPETTPESTPPPETPEFSGYSSFTSTPLPPPNS
AIVEPEIINEKRARKLRKQTKAAHKRALEKKLKTAKMGGLYNEGNTCFMNSIVQALGSLDSLDMLLDEIANAASDDLRSA
KGNKKYLSASTTLTLRDLIHKINTKSTSKHTYSANDLVKSMGSNSERWMSYDQEDAQEYFQQVMNLLERDTKNILHEKDE
DQENEKSKEHPRLLTPFDGETAVRVGCLKCGETEGIRAEVVSSVGLSLEADMREADLYELLHEYTKFEVIPEVECYRCSL
VNMRQSLIDMISEKPIVAEDGTIHPAKAFLPALKERFQTRIEQITEALKQPVIDEKKYEEFQAKGAKERGDKSKQVMFAR
PTARILPIHINRSVFDMRTGYSRKLTVPVTFPVKLDLAPFVVNDVKDPRNLDPRKPMIPTRSETDEKEHEHEDGEDEEEE
EEEEEDEDEESAAAAANTETKHKKHHHGKHKKKAIYKPQPDSLLYNLKAVVVHFGSHNFGHYICFRKCRHNLWWRISDQT
VAQVTEEQALSPQGVFMLFYEQEYEGKLRKEKLKQKRDAQLHEDEEERKKEEAAEATKVDDAPSELVSIGEVDEEEDDEE
DLDEDTGKTTGASRTKQHAKNRGKTE

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination

Molecular Function

GO:0036459 thiol-dependent ubiquitinyl hydrolase activity

Cellular Component

None predicted.