MIA_02533_1

Protein

Length

284 amino acids

Protein function

EGGNOG:	0PHTI	BMH1	14-3-3 protein
SGD closest match:	S000002506	BMH2	Protein BMH2
CGD closest match:	CAL0000198341	BMH1	14-3-3 protein homolog

Protein alignments

	%id	Aln length	E-value
MCA_02991_1	42.128%	235	5.41e-66	MCA_02991_1
A0A0J9X9X4_GEOCN	40.426%	235	2.76e-61	Similar to Saccharomyces cerevisiae YDR099W BMH2 14-3-3 protein OS=Geotrichum candidum GN=BN980_GECA06s02848g PE=3 SV=1
BMH2_YEAST	40.506%	237	5.86e-58	Protein BMH2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BMH2 PE=1 SV=3
UniRef50_P34730	40.506%	237	1.40e-54	Protein BMH2 n=169 Tax=Dikarya TaxID=451864 RepID=BMH2_YEAST
A0A1E3PS62_9ASCO	37.712%	236	4.47e-55	14-3-3 protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48906 PE=3 SV=1
A0A1E4TCL5_9ASCO	41.810%	232	4.19e-55	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_139812 PE=3 SV=1
1433_CANAL	38.865%	229	6.12e-55	14-3-3 protein homolog OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BMH1 PE=3 SV=2
A0A060TCT0_BLAAD	37.712%	236	1.42e-54	ARAD1D02046p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D02046g PE=3 SV=1
A0A167CD18_9ASCO	36.752%	234	2.88e-54	14-3-3 family protein BMH2 OS=Sugiyamaella lignohabitans GN=BMH2 PE=3 SV=1
F2Z6F8_YARLI	36.709%	237	9.90e-51	YALI0B14377p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B14377g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0645

Protein family membership

14-3-3 protein (IPR000308)

Domains and repeats

Domain
51 - 284
14-3-3 domain (IPR023410)

1 50 100 150 200 250 284

Detailed signature matches

IPR000308

14-3-3 protein
1. PR00305 (1433ZETA)
  
  162 - 184
  
  PRINTS
  PR00305 (1433ZETA)
  
  251 - 280
  
  PRINTS
  PR00305 (1433ZETA)
  
  224 - 250
  
  PRINTS
  PR00305 (1433ZETA)
  
  84 - 113
  
  PRINTS
  PR00305 (1433ZETA)
  
  131 - 155
  
  PRINTS
  PR00305 (1433ZETA)
  
  197 - 223
  
  PRINTS
  PR00305 (1433ZETA)
2. PIRSF000868 (14-3-3)
  
  46 - 284
  
  PIRSF
  PIRSF000868 (14-3-3)
IPR023410

14-3-3 domain
1. PF00244 (14-3-3)
  
  58 - 278
  
  Pfam
  PF00244 (14-3-3)
2. SM00101 (1433_4)
  
  52 - 284
  
  SMART
  SM00101 (1433_4)
3. G3DSA:1.20.19...
  
  53 - 284
  
  GENE3D
  G3DSA:1.20.190.20 (G3DSA:1.20.190.20)
4. SSF48445 (14-3-3 pr...)
  
  51 - 280
  
  SUPERFAMILY
  SSF48445 (14-3-3 protein)

no IPR

Unintegrated signatures

cd08774 (14-3-3)

54 - 275

CDD
cd08774 (14-3-3)
mobidb-lite (disord...)

1 - 49

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

dimer interface cd...

58L

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

61F

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

62S

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

64K

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

65A

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

67R

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

70D

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

107S

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

110A

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

114K

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

127L

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

131Y

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

134K

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

135I

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)

138E

dimer interface
58L, 61F, 62S, 64K, 65A, 67R, 70D, 107S, 110A, 114K, 127L, 131Y, 134K, 135I, 138E
CDD
cd08774 (14-3-3)
peptide binding si...

98K

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

105K

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

169L

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

176R

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

177F

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

218R

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

221L

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

222N

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

225V

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

228H

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

229V

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

266L

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

269A

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

272D

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

273N

peptide binding site
98K, 105K, 169L, 176R, 177F, 218R, 221L, 222N, 225V, 228H, 229V, 266L, 269A, 272D, 273N
CDD
cd08774 (14-3-3)

Protein sequence

>MIA_02533_1
MRLANQNSSPPTEVQSPLNNDLHDESQPTTTTSAHLKHHSKKKHEQKTTLSRADALLLAQFSEKAQRYDDMAKYMKAVVN
HGGELNTQEQWLLSNAFKQAVQTRKLSLKALFSKPDDTTKDAAATELLDEYKSKIKQELTEFCCDILELLESNLIPGVKT
DKSKAFYFLLKGDFYRFLADFHFDSNGEQIIQEALDAYVFASNLAHKTLPCTDSVRLRIALNFSVFYHVILQDTQKAQRI
ARPAFDSAIDHLEELTTDNYEEVTALLHAIRDNLNVWDSQLAKS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0019904 protein domain specific binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MIA_02533_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component