Protein

MIA_02496_1

Length
383 amino acids


Browser: contig03:968894-970046+

Protein function

EGGNOG:0PG9IFG00478.1Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
SGD closest match:S000002442ARO3Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited
CGD closest match:CAL0000176586ARO3Phospho-2-dehydro-3-deoxyheptonate aldolase

Protein alignments

%idAln lengthE-value
MCA_04144_176.364%3850.0MCA_04144_1
A0A0J9XEY2_GEOCN73.458%3730.0Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Geotrichum candidum GN=BN980_GECA13s02903g PE=3 SV=1
A0A1E3PSP7_9ASCO69.761%3770.0Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45010 PE=3 SV=1
A0A060T2T9_BLAAD69.333%3750.0Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A11132g PE=3 SV=1
A0A1D8PGI8_CANAL67.200%3750.0Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ARO3 PE=3 SV=1
A0A1E4TF03_9ASCO68.800%3750.0Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_105028 PE=3 SV=1
A0A167ECD3_9ASCO67.895%3800.0Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Sugiyamaella lignohabitans GN=ARO3 PE=3 SV=1
AROF_YEAST63.492%3780.0Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARO3 PE=1 SV=1
Q6CDZ3_YARLI63.807%3737.94e-178Phospho-2-dehydro-3-deoxyheptonate aldolase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B20020g PE=3 SV=1
UniRef50_A0A1W5CUU963.298%3762.27e-165Phospho-2-dehydro-3-deoxyheptonate aldolase n=1 Tax=Umbilicaria pustulata TaxID=136370 RepID=A0A1W5CUU9_9LECA

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1254

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 383

Detailed signature matches

    1. PIRSF001361 (DAHP_s...)
    1. PF00793 (DAHP_synth_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF51569 (Aldolase)

Protein sequence

>MIA_02496_1
MYLKNQNLGDRSSLEDHRIRGYDPLIAPDLLQSMYPLSEASSNHILEARTAATAVLEGRDDRLIVVVGPCSIHDPKSALD
YADRLAKLNESLKDDLLIIMRAYMEKPRTTVGWKGLINDPDIDGTFNINKGLRVTRELLSTITEKIAIAGEMLDTISPQF
ISDLFSLGAIGARTTESQLHRELASGLSFPVGFKNGTDGGLDVAIDAVRAANHPHHFLSTTKPGGLAIVGTNGNEDCFII
LRGGKTGTNYDAKSVAAAESKLRAAGIAKDNEQTGRAYPRVMVDCSHGNSSKNYKNQPIVAAEVARQLSAGSSSLCGVMI
ESHIAEGSQKVPDLKDGGKDALKYGVSITDSCIGWDTTVNVLEELAAAVRTRREVFKQKKLSN

GO term prediction

Biological Process

GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity

Cellular Component

None predicted.