Protein

MIA_02353_1

Length
546 amino acids


Browser: contig03:553229-554922-

Protein function

EGGNOG:0PI16FG09892.1Retinoblastoma-binding protein
SGD closest match:S000001542MPE1Protein MPE1
CGD closest match:CAL0000185514orf19.4628Cleavage polyadenylation factor subunit

Protein alignments

%idAln lengthE-value
MCA_01809_161.29%3413e-140MCA_01809_1
A0A0J9X924_GEOCN57.82%3392e-114Similar to Saccharomyces cerevisiae YKL059C MPE1 Essential conserved subunit of CPF (Cleavage and polyadenylation factor) OS=Geotrichum candidum GN=BN980_GECA05s06456g PE=4 SV=1
A0A060SX09_BLAAD54.19%3344e-99ARAD1A04950p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A04950g PE=4 SV=1
A0A1E3PS31_9ASCO48.84%3466e-96DWNN-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_6191 PE=4 SV=1
UniRef50_A0A1E3PS3148.84%3462e-92DWNN-domain-containing protein (Fragment) n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3PS31_9ASCO
Q6CHE1_YARLI45.50%3672e-78YALI0A09834p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A09834g PE=4 SV=1
A0A1E4TB52_9ASCO44.35%3367e-78Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32374 PE=4 SV=1
A0A167DKW0_9ASCO46.26%2817e-62Mpe1p OS=Sugiyamaella lignohabitans GN=MPE1 PE=4 SV=1
MPE1_YEAST39.03%3511e-59Protein MPE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MPE1 PE=1 SV=1
A0A1D8PLB3_CANAL33.59%3937e-47Cleavage polyadenylation factor subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4628 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3605

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 546

Detailed signature matches

    1. PF08783 (DWNN)
    2. SM01180 (DWNN_2)
    3. PS51282 (DWNN)
    1. SM00343 (c2hcfinal6)
    2. SSF57756 (Retroviru...)
    3. PS50158 (ZF_CCHC)
    1. PF13696 (zf-CCHC_2)
    1. PF04564 (U-box)
    2. SM00504 (Ubox_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF57850 (RING/U-box)
  2. cd16620 (vRING-HC-C...)
  3. mobidb-lite (disord...)

Residue annotation

  1. homodimer interfac...
  2. Zn binding site cd...

Protein sequence

>MIA_02353_1
MASVVYYKFKSQKDPSRILFEGTGISVFDLKKEILLENKLVDTANNFDLEISNPDTKEAYDDDTEVIPRSVSVSARRIPA
SRPGKGTAIYYVTGNMTNVSKQINTKKDDPKKKSSAPGGDTEDDKINAMFQTQDEQWEQTQERMATAQRIYNKPAQPKGV
PGPRYICQNCGKTGHYRSDCPMGNDRRYKPTTGIPRSFLKTIDAPKDNDTGTYMVNGDGQVVVAVADENSWKNFQTKAKK
SQLLNDKPDDPELEDPISHKLLVKPVKTPCCGTTYSEETIQQVLSDSGVCPKCGQDVSLDQLVPDDRMIERLREYKAAKE
QKRLEEEANGGPTSNTATPTATPAQLATSGSPGSTKRKRDDESSEPESGAEGEGEERKKKKTGSAEPEVLEVSTKTPDTA
SVPLSTTPDPNALLNWNPSMISGMPPMPMMMPGMPPMMPFMGMMPPGMPAGMPPMPPMMPGMPSPFLPGTNFNNGGFNNS
TPNATTNNNNYNNYNNNNGHNGNNNHNHSYNYNNNNNNNNFRGGSRNNNNRRRNYNRNRDTDFHVL

GO term prediction

Biological Process

GO:0016567 protein ubiquitination

Molecular Function

GO:0003676 nucleic acid binding
GO:0004842 ubiquitin-protein transferase activity
GO:0008270 zinc ion binding

Cellular Component

GO:0005634 nucleus