Protein

MIA_02346_1

Length
1,205 amino acids

Browser: contig03:526764-530539+

Protein function

EGGNOG:0PH6IPGUG_00574coatomer
SGD closest match:S000002304COP1Coatomer subunit alpha
CGD closest match:CAL0000197947orf19.1672Coatomer subunit alpha

Protein alignments

%idAln lengthE-value
MCA_05408_174.028%12090.0MCA_05408_1
A0A0J9X5Z5_GEOCN66.969%12110.0Coatomer subunit alpha OS=Geotrichum candidum GN=BN980_GECA03s04465g PE=4 SV=1
A0A060T9Z0_BLAAD62.266%12270.0Coatomer subunit alpha OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22946g PE=4 SV=1
A0A1E3PNG1_9ASCO59.069%12460.0Coatomer subunit alpha OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45210 PE=4 SV=1
A0A170QZ78_9ASCO61.513%11900.0Coatomer subunit alpha OS=Sugiyamaella lignohabitans GN=COP1 PE=4 SV=1
UniRef50_A0A084GDQ455.774%12210.0Uncharacterized protein n=1 Tax=Scedosporium apiospermum TaxID=563466 RepID=A0A084GDQ4_9PEZI
A0A1E4THD3_9ASCO51.412%12390.0Coatomer subunit alpha OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_117644 PE=4 SV=1
COPA_YEAST52.007%12210.0Coatomer subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COP1 PE=1 SV=2
Q6C5A1_YARLI62.659%8650.0Coatomer subunit alpha OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E19767g PE=4 SV=1
A0A1D8PJB0_CANAL61.313%8530.0Coatomer subunit alpha OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1672 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1164
Predicted cleavage: 15

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
  4. Repeat
  5. Repeat
1 200 400 600 800 1000 1205

Detailed signature matches

  1. Family IPR016391
    Coatomer alpha subunit
    1. PIRSF003354 (Alpha-COP)
  2. Domain IPR015943
    WD40/YVTN repeat-like-containing domain
    1. G3DSA:2.130.1...
  3. Domain IPR017986
    WD40-repeat-containing domain
    1. SSF50978 (WD40 repe...)
    2. PS50294 (WD_REPEATS...)
  4. Domain IPR006692
    Coatomer, WD associated region
    1. PF04053 (Coatomer_WDAD)
  5. Domain IPR011990
    Tetratricopeptide-like helical domain
    1. G3DSA:1.25.40.10
  6. Domain IPR010714
    Coatomer, alpha subunit, C-terminal
    1. PF06957 (COPI_C)
  7. Repeat IPR001680
    WD40 repeat
    1. PF00400 (WD40)
    2. PS50082 (WD_REPEATS_2)
    3. SM00320 (WD40_4)
  8. Repeat IPR020472
    G-protein beta WD-40 repeat
    1. PR00320 (GPROTEINBRPT)
  9. SITE IPR019775
    WD40 repeat, conserved site
    1. PS00678 (WD_REPEATS_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.10...
  2. SSF82171 (DPP6 N-te...)
  3. cd00200 (WD40)

Residue annotation

  1. structural tetrad ...

Protein sequence

>MIA_02346_1
MQMLTKFESKSSRAKGVAFHPKRPWILVSLHSSTIQLWDYRMGTLIDRFEGHDGPVRGIDFHKTQPLFVSCGDDYTVKVW
SLQTRKLLFTLNGHLDYVRTVFFHNDLPWIISASDDQTIRIWNWQNRQEIACLTGHNHYVLCAQFHPSEDLIVSASLDQT
VRVWDISGLRKKHSAPTQITTSFEDQLARANSSQQDIFGNTDAIVKFVLEGHDRGVNWVAFHPTLPLIVSGGDDRLVKVW
RMSESRAWQVDSCVGHTHNVLCCVFHPFQDLIISVSEDKTIRVWDLNKRTLIQQFKRDNDKFWYIAAHSTINLFAAAHDS
GVMVFKLERERPASVLNDNTLFYVTKDKLVKSFDFTTDTESNPLVSLKKIGDPWAPFRTISYNPSEKFVLVTIKADNENI
YELQQLSGNSPSIHSNISGSQLGGRGDAALFINRQRFAVFNKSSQTIQIYDMNNNVTRVVKVGSNPIKDMVPGGPSLGLV
LLLGASSVTLFDLQQEKVIAKAPVNGVKYTSWSKDGKYVALIGKHQITIANRDLKVLASLHETIRIKSAVWDDNGVLLYS
TLNHLKYSLLNGDHGILKTLENTVYLIKIKDNLVYVLTRNGNIEIIEIDPTEYRFKRALLNKNFNEVLRLIKTSNLVGQN
IIGYLQQKGYSEIALQFVQDPQTRFGLAIECGNLNVALEQANELKKPAVWSILGKEALDQGNHEIAELAYQKQSQFDKLS
FLYLTTGNYAKLEKMGAIASHRGDVNAQFTNDLYLGNVISRIEILKAAGHDALAYSLAKSNGLTDVAQQILEESGVEESN
INVSITDRTSLPQAPPVLNPLAGFNWPLKNTSLSFFEQAILGQVDNLSLEEPDTQDNVDAIADIDAYDAYEDDEVQDDAW
GLEEDEIAVEEQSHDTSAHAGVSEIELWTQNSPLAADHIAAGSFESAVQILHRQLGITAIAPLKSRFLEIYQASKVYLPA
TEILPSLPVFVRRNPTETNPLKSLPIIPGYDQLKPTLQEAFKAVMQNKPELAISLFRKILYIIATLAVTTQSEVEECEKL
IKISKEYILAFSIELERRSLPPTEIKRRLELAVYFTKPTLEPQHAFIPLRVAMVESFNHKNFGSASAFAGKLLKIIGNNN
KISERARTIKEKADKSPRDNVDIDYDHFADFDICPATLTPVYSGTASVTDPYTGAVYHESAKGTLCKITGITTVGASATG
LRLKI

GO term prediction

Biological Process

GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport

Molecular Function

GO:0005198 structural molecule activity
GO:0005515 protein binding

Cellular Component

GO:0030117 membrane coat
GO:0030126 COPI vesicle coat