Protein

MIA_02340_1

Length
769 amino acids


Browser: contig03:513593-515903+

Protein function

EGGNOG:0PGI6SEC23Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity)
SGD closest match:S000006385SEC23Protein transport protein SEC23
CGD closest match:CAL0000192101SEC23Protein transport protein SEC23

Protein alignments

%idAln lengthE-value
MCA_04163_175.457%7660.0MCA_04163_1
A0A060T3C0_BLAAD71.802%7660.0ARAD1C36102p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C36102g PE=4 SV=1
A0A1E3PFR6_9ASCO69.599%7730.0Protein transport protein SEC23 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83797 PE=4 SV=1
A0A0J9XBZ8_GEOCN70.511%7630.0Similar to Saccharomyces cerevisiae YPR181C SEC23 GTPase-activating protein, stimulates the GTPase activity of Sar1p OS=Geotrichum candidum GN=BN980_GECA08s03486g PE=4 SV=1
SEC23_YARLI64.499%7690.0Protein transport protein SEC23 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=SEC23 PE=3 SV=2
UniRef50_A0A139H0U360.311%7710.0Uncharacterized protein n=4 Tax=Dikarya TaxID=451864 RepID=A0A139H0U3_9PEZI
A0A1E4TJX3_9ASCO58.991%7730.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_47375 PE=4 SV=1
SEC23_CANAL55.339%7680.0Protein transport protein SEC23 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SEC23 PE=3 SV=2
SEC23_YEAST54.334%7730.0Protein transport protein SEC23 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC23 PE=1 SV=1
A0A167CYY8_9ASCO68.325%6030.0GTPase-activating protein SEC23 OS=Sugiyamaella lignohabitans GN=SEC23 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0113

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 769

Detailed signature matches

    1. PF04810 (zf-Sec23_S...)
    2. SSF82919 (Zn-finger...)
    1. SSF53300 (vWA-like)
    1. PF04811 (Sec23_trunk)
    1. PF08033 (Sec23_BS)
    1. PF04815 (Sec23_helical)
    2. SSF81811 (Helical d...)
    1. SSF82754 (C-termina...)
    2. PF00626 (Gelsolin)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF81995 (beta-sand...)
  2. cd11287 (Sec23_C)

Residue annotation

  1. Sar1 interface cd1...
  2. catalytic residue ...

Protein sequence

>MIA_02340_1
MQAEFENAEEIDGVRFSWNSFPNTKIEASRTVIPIASLYTPLREKPDLPILQYDPIICKSPCRAVLNPYCQLDLRSRVWV
CPFCLSRNPLPPHYKEISQASLPHELLPTSTTIEYVLSRPAAVPPIFLFVVDTCQDNENLQALKDTLIVSLSLIPPNALV
GLITFGSMVFLHEVGYTECSKLHVFRGDKEVTPKDLQTKLGLNPHPTSMAPGNHAQNPAAAMLQQGYSRFLQPVQECEFQ
LTSIIEKIQKDMWLVPNDKRHTRCTGSALSVAISLLEHNFPGTGARVMLFAAGPPTKGPGLVVSADLKERLRSHHNIANQ
SAPHFDKAVKFYEGLAKRASSNGHAVDLCVGCYDQVGLQEMSSLANSTGGVMILSDAFTTSIFKQSVQRIFAKDSNGFLQ
MGFNASMDVHTTKELKITGFIGHGVSLNKRSPCVSDTEIGIGRTSAWKMSSITPAHTYATYFEIVSQGGTNNSTQHKSNQ
RALIQYITHYQHSSGTLRLRVTTLARALVAGGSPDVALSFDQEAAAVIMARIAVYKAEMEGSPDILRWIDRTLINLCQKF
ADYRKGDPSTFCLLGNFSLYPQFMYHLRRSQFLQVFNNSPDETAFYRHCLNREDLTNSLIMIQPTLISFTFGRPPEPVLL
DSVSIKPDAILLLDTFFHILIFHGENIAQWRKAGFQDQENHANFRELLAAPRKEASELLIDRFPLPRFIDTDAGGSQARF
LLSRLNPSATPKNAETYGGFSAGTTVVLTDDVSLQTFMEHLQQTVVMAS

GO term prediction

Biological Process

GO:0006886 intracellular protein transport
GO:0006888 ER to Golgi vesicle-mediated transport

Molecular Function

GO:0008270 zinc ion binding

Cellular Component

GO:0030127 COPII vesicle coat