Protein

MIA_02143_1

Length
903 amino acids

Browser: contig02:2740431-2743204-

Protein function

EGGNOG:0PJ0ZTIF32Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity)
SGD closest match:S000000283RPG1Eukaryotic translation initiation factor 3 subunit A
CGD closest match:CAL0000181001RPG1AEukaryotic translation initiation factor 3 subunit A

Protein alignments

%idAln lengthE-value
MCA_02784_173.087%7840.0MCA_02784_1
A0A0J9XJP1_GEOCN69.755%7770.0Eukaryotic translation initiation factor 3 subunit A OS=Geotrichum candidum GN=TIF32 PE=3 SV=1
A0A170R049_9ASCO59.250%7730.0Eukaryotic translation initiation factor 3 subunit A OS=Sugiyamaella lignohabitans GN=RPG1 PE=3 SV=1
A0A060TIM1_BLAAD64.966%5880.0Eukaryotic translation initiation factor 3 subunit A OS=Blastobotrys adeninivorans GN=TIF32 PE=3 SV=1
A0A1E3PJI0_9ASCO51.737%7770.0Eukaryotic translation initiation factor 3 subunit A OS=Nadsonia fulvescens var. elongata DSM 6958 GN=TIF32 PE=3 SV=1
EIF3A_YARLI58.725%5960.0Eukaryotic translation initiation factor 3 subunit A OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=TIF32 PE=3 SV=1
UniRef50_Q6C16158.725%5960.0Eukaryotic translation initiation factor 3 subunit A n=6 Tax=Saccharomycetales TaxID=4892 RepID=EIF3A_YARLI
A0A1E4TEZ9_9ASCO44.198%7671.06e-164Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_16415 PE=3 SV=1
EIF3A_CANAL41.220%8203.27e-155Eukaryotic translation initiation factor 3 subunit A OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPG1A PE=3 SV=2
EIF3A_YEAST40.711%5061.89e-106Eukaryotic translation initiation factor 3 subunit A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPG1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1042

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 903

Detailed signature matches

  1. Family IPR027512
    Eukaryotic translation initiation factor 3 subunit A
    1. MF_03000 (eIF3a)
  2. Domain IPR000717
    Proteasome component (PCI) domain
    1. SM00088 (PINT_4)
    2. PF01399 (PCI)
  3. Domain IPR011991
    Winged helix-turn-helix DNA-binding domain
    1. G3DSA:1.10.10.10
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. SM00753 (PINT)
  3. mobidb-lite (disord...)

Protein sequence

>MIA_02143_1
MAPAARPENVLKRADELIAVDQSTAALELLYETLTSKRTRSVTIENLEPIILRFIDLAVDLNKPKIIRDGLYQYKKLVQS
TSVSSLELVIKKFIQLSEDKVAQAQAKADKIILDADEDLEATESPEDILLATVSSEQSKDRTDREVVTPWLKLLWEAYRI
SLDALRNNSKLEILYQKVVFQAFDFCVNYSRKTEFRRLCDILRLHLSNASQTKSSPAQHPIDLSDPDTLQRFLDTRFHQL
EVAVKLELWQEAFRSVEDVHTLLSVSKRPAKPAMMANYYDNLARIFLVSGNYLFHATAWSRYWGLLVQSRNVREEELIRV
ASFFLIATLSIPTFPQSQQLHSSQDDGDQRHRNSRLTNLLNLSKNPTRDALLKQALSKNVLSYVRPEIRQLYNILEVDFH
PLGIKSRIVPVISKIAEYKEYAPYFKPLYDVILTRLFQQLSQVYETVKFDFVIDLATFPAPFDSTPVSIEKFIVRGCHKG
EFNITIDHESRSITFRDGIYDESSVNSSIAASASSLQLTPSEIVRTQLSRLGSTLFSVINQVDVSYIEEHARLRKQAIDR
ALAGLKDENLKTLERIKVIERRQQAAIEEQIKREEEESRALRRKLQEEREAEKQRLAKEAAAREEERRKREENEIIAREK
RRLAEDINSKGIISIDVTKLDEMDSAQIRALQIKEFNKVSEDLNKKLKSIARHNDHIERALRMEEISKWQEEAKKQQEAD
KKVHETRYAALLASSKKEHDEKLALKKRLIRLLPSFQELKDTVYAARKEEFERLKKVNAEKLEEEKAKRLAEAKKQRAFE
REQEQLRVEEESRLQREKNKRIRDEEEKAKRERAEAAAAASAAPASSSSGAYRPPNRETSAGGSKYVPPSRRTRDAPSQA
PSSSGTPAPSSGGSRYVPPSRRR

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

GO:0005852 eukaryotic translation initiation factor 3 complex