MIA_02098_1

Protein

Length

1,622 amino acids

Protein function

EGGNOG:	0PGRZ	FG05182.1	domain-containing protein
SGD closest match:	S000000143	EDE1	EH domain-containing and endocytosis protein 1
CGD closest match:	CAL0000185742	CTA3	Cta3p

Protein alignments

	%id	Aln length	E-value
MCA_04360_1	46.228%	729	2.56e-138	MCA_04360_1
Q6CAW1_YARLI	35.310%	725	1.28e-89	YALI0C23903p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C23903g PE=4 SV=1
A0A0J9XJ12_GEOCN	40.034%	587	7.99e-87	Similar to Saccharomyces cerevisiae YBL047C EDE1 Endocytic protein involved in a network of interactions with other endocytic proteins OS=Geotrichum candidum GN=BN980_GECA18s00516g PE=4 SV=1
A0A060TBR9_BLAAD	47.978%	371	1.64e-82	ARAD1D34232p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D34232g PE=4 SV=1
UniRef50_A0A0J9XCA0	45.722%	374	1.19e-75	Similar to Saccharomyces cerevisiae YBL047C EDE1 Endocytic protein involved in a network of interactions with other endocytic proteins n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCA0_GEOCN
A0A1E3PLJ4_9ASCO	38.765%	583	2.11e-78	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50228 PE=4 SV=1
A0A1E4TKE6_9ASCO	33.558%	593	1.16e-59	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30459 PE=4 SV=1
A0A167FKB8_9ASCO	45.992%	237	3.04e-54	Ede1p OS=Sugiyamaella lignohabitans GN=EDE1 PE=4 SV=1
EDE1_YEAST	32.787%	366	1.12e-38	EH domain-containing and endocytosis protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EDE1 PE=1 SV=2
A0A1D8PF53_CANAL	33.613%	238	2.82e-33	Cta3p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CTA3 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0048

Protein family membership

None predicted.

Domains and repeats

Domain
7 - 114
EF-hand domain pair (IPR011992)
EH domain (IPR000261)
EF-hand domain (IPR002048)
133 - 229
EF-hand domain pair (IPR011992)
EH domain (IPR000261)
EF-hand domain (IPR002048)
288 - 390
EF-hand domain pair (IPR011992)
EH domain (IPR000261)
EF-hand domain (IPR002048)
1,559 - 1,619
UBA-like (IPR009060)
Ubiquitin-associated domain (IPR015940)

1 200 400 600 800 1000 1200 1400 1622

Detailed signature matches

IPR011992

EF-hand domain pair
1. SSF47473 (EF-hand)
  
  134 - 223
  
  SUPERFAMILY
  SSF47473 (EF-hand)
  
  288 - 388
  
  SUPERFAMILY
  SSF47473 (EF-hand)
  
  11 - 93
  
  SUPERFAMILY
  SSF47473 (EF-hand)
IPR000261

EH domain
1. SM00027 (eh_3)
  
  7 - 102
  
  SMART
  SM00027 (eh_3)
  
  133 - 228
  
  SMART
  SM00027 (eh_3)
  
  294 - 389
  
  SMART
  SM00027 (eh_3)
2. PF12763 (EF-hand_4)
  
  296 - 386
  
  Pfam
  PF12763 (EF-hand_4)
  
  137 - 221
  
  Pfam
  PF12763 (EF-hand_4)
3. PS50031 (EH)
  
  301 - 390
  
  PROSITE profiles
  PS50031 (EH)
  
  140 - 229
  
  PROSITE profiles
  PS50031 (EH)
  
  14 - 114
  
  PROSITE profiles
  PS50031 (EH)
IPR002048

EF-hand domain
1. PS50222 (EF_HAND_2)
  
  13 - 48
  
  PROSITE profiles
  PS50222 (EF_HAND_2)
  
  171 - 206
  
  PROSITE profiles
  PS50222 (EF_HAND_2)
  
  334 - 369
  
  PROSITE profiles
  PS50222 (EF_HAND_2)
IPR009060

UBA-like
1. SSF46934 (UBA-like)
  
  1,559 - 1,619
  
  SUPERFAMILY
  SSF46934 (UBA-like)
IPR015940

Ubiquitin-associated domain
1. SM00165 (uba_6)
  
  1,581 - 1,618
  
  SMART
  SM00165 (uba_6)
2. PF00627 (UBA)
  
  1,582 - 1,616
  
  Pfam
  PF00627 (UBA)
3. PS50030 (UBA)
  
  1,580 - 1,619
  
  PROSITE profiles
  PS50030 (UBA)

no IPR

Unintegrated signatures

Coil

659 - 749

COILS
Coil (Coil)

624 - 651

COILS
Coil (Coil)

561 - 595

COILS
Coil (Coil)
G3DSA:1.10.23...

111 - 231

GENE3D
G3DSA:1.10.238.10 (G3DSA:1.10.238.10)

2 - 109

GENE3D
G3DSA:1.10.238.10 (G3DSA:1.10.238.10)

280 - 392

GENE3D
G3DSA:1.10.238.10 (G3DSA:1.10.238.10)
G3DSA:1.10.8.10

1,524 - 1,622

GENE3D
G3DSA:1.10.8.10 (G3DSA:1.10.8.10)
G3DSA:1.20.11...

412 - 778

GENE3D
G3DSA:1.20.1170.10 (G3DSA:1.20.1170.10)
cd00052 (EH)

144 - 203

CDD
cd00052 (EH)

18 - 79

CDD
cd00052 (EH)

306 - 370

CDD
cd00052 (EH)
cd14297 (UBA2_spUBP...)

1,583 - 1,618

CDD
cd14297 (UBA2_spUBP14_like)
mobidb-lite (disord...)

785 - 936

MobiDB Lite
mobidb-lite (disorder_prediction)

1,105 - 1,204

MobiDB Lite
mobidb-lite (disorder_prediction)

1,233 - 1,259

MobiDB Lite
mobidb-lite (disorder_prediction)

390 - 482

MobiDB Lite
mobidb-lite (disorder_prediction)

1,454 - 1,542

MobiDB Lite
mobidb-lite (disorder_prediction)

725 - 758

MobiDB Lite
mobidb-lite (disorder_prediction)

1,280 - 1,395

MobiDB Lite
mobidb-lite (disorder_prediction)

232 - 297

MobiDB Lite
mobidb-lite (disorder_prediction)

968 - 1,090

MobiDB Lite
mobidb-lite (disorder_prediction)

102 - 141

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

pseudo EF-hand loo...

24Q

pseudo EF-hand loop
24Q, 25C, 26D, 33V, 34T, 35G, 36D, 37V
CDD
cd00052 (EH)

25C

pseudo EF-hand loop
24Q, 25C, 26D, 33V, 34T, 35G, 36D, 37V
CDD
cd00052 (EH)

26D

pseudo EF-hand loop
24Q, 25C, 26D, 33V, 34T, 35G, 36D, 37V
CDD
cd00052 (EH)

33V

pseudo EF-hand loop
24Q, 25C, 26D, 33V, 34T, 35G, 36D, 37V
CDD
cd00052 (EH)

34T

pseudo EF-hand loop
24Q, 25C, 26D, 33V, 34T, 35G, 36D, 37V
CDD
cd00052 (EH)

35G

pseudo EF-hand loop
24Q, 25C, 26D, 33V, 34T, 35G, 36D, 37V
CDD
cd00052 (EH)

36D

pseudo EF-hand loop
24Q, 25C, 26D, 33V, 34T, 35G, 36D, 37V
CDD
cd00052 (EH)

37V

pseudo EF-hand loop
24Q, 25C, 26D, 33V, 34T, 35G, 36D, 37V
CDD
cd00052 (EH)
peptide binding po...

42F

peptide binding pocket
42F, 52L, 56W
CDD
cd00052 (EH)

52L

peptide binding pocket
42F, 52L, 56W
CDD
cd00052 (EH)

56W

peptide binding pocket
42F, 52L, 56W
CDD
cd00052 (EH)
Ca2+ binding site ...

60D

Ca2+ binding site
60D, 62L, 64H, 71G
CDD
cd00052 (EH)

62L

Ca2+ binding site
60D, 62L, 64H, 71G
CDD
cd00052 (EH)

64H

Ca2+ binding site
60D, 62L, 64H, 71G
CDD
cd00052 (EH)

71G

Ca2+ binding site
60D, 62L, 64H, 71G
CDD
cd00052 (EH)
pseudo EF-hand loo...

150K

pseudo EF-hand loop
150K, 151N, 152A, 157L, 158N, 159G, 160T, 161D
CDD
cd00052 (EH)

151N

pseudo EF-hand loop
150K, 151N, 152A, 157L, 158N, 159G, 160T, 161D
CDD
cd00052 (EH)

152A

pseudo EF-hand loop
150K, 151N, 152A, 157L, 158N, 159G, 160T, 161D
CDD
cd00052 (EH)

157L

pseudo EF-hand loop
150K, 151N, 152A, 157L, 158N, 159G, 160T, 161D
CDD
cd00052 (EH)

158N

pseudo EF-hand loop
150K, 151N, 152A, 157L, 158N, 159G, 160T, 161D
CDD
cd00052 (EH)

159G

pseudo EF-hand loop
150K, 151N, 152A, 157L, 158N, 159G, 160T, 161D
CDD
cd00052 (EH)

160T

pseudo EF-hand loop
150K, 151N, 152A, 157L, 158N, 159G, 160T, 161D
CDD
cd00052 (EH)

161D

pseudo EF-hand loop
150K, 151N, 152A, 157L, 158N, 159G, 160T, 161D
CDD
cd00052 (EH)
peptide binding po...

166F

peptide binding pocket
166F, 176L, 180W
CDD
cd00052 (EH)

176L

peptide binding pocket
166F, 176L, 180W
CDD
cd00052 (EH)

180W

peptide binding pocket
166F, 176L, 180W
CDD
cd00052 (EH)
Ca2+ binding site ...

184D

Ca2+ binding site
184D, 186K, 188R, 195E
CDD
cd00052 (EH)

186K

Ca2+ binding site
184D, 186K, 188R, 195E
CDD
cd00052 (EH)

188R

Ca2+ binding site
184D, 186K, 188R, 195E
CDD
cd00052 (EH)

195E

Ca2+ binding site
184D, 186K, 188R, 195E
CDD
cd00052 (EH)
pseudo EF-hand loo...

311S

pseudo EF-hand loop
311S, 312L, 313D, 320I, 321G, 322A, 323E, 324E
CDD
cd00052 (EH)

312L

pseudo EF-hand loop
311S, 312L, 313D, 320I, 321G, 322A, 323E, 324E
CDD
cd00052 (EH)

313D

pseudo EF-hand loop
311S, 312L, 313D, 320I, 321G, 322A, 323E, 324E
CDD
cd00052 (EH)

320I

pseudo EF-hand loop
311S, 312L, 313D, 320I, 321G, 322A, 323E, 324E
CDD
cd00052 (EH)

321G

pseudo EF-hand loop
311S, 312L, 313D, 320I, 321G, 322A, 323E, 324E
CDD
cd00052 (EH)

322A

pseudo EF-hand loop
311S, 312L, 313D, 320I, 321G, 322A, 323E, 324E
CDD
cd00052 (EH)

323E

pseudo EF-hand loop
311S, 312L, 313D, 320I, 321G, 322A, 323E, 324E
CDD
cd00052 (EH)

324E

pseudo EF-hand loop
311S, 312L, 313D, 320I, 321G, 322A, 323E, 324E
CDD
cd00052 (EH)
peptide binding po...

329L

peptide binding pocket
329L, 339L, 343W
CDD
cd00052 (EH)

339L

peptide binding pocket
329L, 339L, 343W
CDD
cd00052 (EH)

343W

peptide binding pocket
329L, 339L, 343W
CDD
cd00052 (EH)
Ca2+ binding site ...

347D

Ca2+ binding site
347D, 349N, 351T, 358E
CDD
cd00052 (EH)

349N

Ca2+ binding site
347D, 349N, 351T, 358E
CDD
cd00052 (EH)

351T

Ca2+ binding site
347D, 349N, 351T, 358E
CDD
cd00052 (EH)

358E

Ca2+ binding site
347D, 349N, 351T, 358E
CDD
cd00052 (EH)

Protein sequence

>MIA_02098_1
MSDGLSAKQYTQTETSAFEALLSQCDPTHSGYVTGDVARGLFMQSGLQPVLLGQIWQLADPLNHGYLDKNGFFLALRIIG
HVQSGQQLTTALGDSVITSPQQTTSSLVTPSSPLQQQQQAPASPSSTTSPTQIPPISPQDRSSYSQIFIKNAPSGLLNGT
DARNIFVKSKLPNETLIQVWNLSDTKNRGQLDQPEFILAMHLIRSTLSGTLKQLPSSLPQGFFEAFTQNHRVPSITSPAP
PAPPAPRSAASLQTSPRPQTSTIGSPVPASAPQFTGQQINPPSRSSTFGSNPNEWKISPSEHAKSDAIFASLDTHHRGVI
GAEEVVPFLTKSNLPEEVLAQVWDLADVNNTGQFRKPEFAIAMYLVQQKLLGRDLPLNLPNSLNPSYTAAVPPSESLLSS
PVATSPPPIPPKTSINAPPQQPPKIQTTSSSLHDLVSLGDSFVSPTVKSPPQSLSQPNTATRDFSGTSTRSNTSFTPVSN
FGQNLARESVPVAASTNQTSSPLTSAGFAAGAALGAVAGTAAGAVSSAFQPKQLNLLHQPDELDNKVSTIKTDVANLQNQ
VTSMSTQTDAARQKREKAEAEIARLDGVKSDLETKLTSLRSTHSSEVKRHEQLDQLLHKNQLEAGKLSQEYSTLEATYAS
LQTQIQDTTNKFNADQQESATVKENIKKVNEEIEKLKKDLEKIQREAKQQGNLLSISKQQLATAEQERDSLKKSIEEAAA
AAAAAERENQEIQRQIEQAKQEQQQLHSTRGAQTSSSSAVPGIAAGLTGGAALGAAAVAAFNSTSADGTSAPATAGVATT
ETPVSTSSTNPFYATSFAPPPSSDTATVSPVPFEDHFGLNTPSTADPSRNFTYNDTPNTSPNSDFTNNPTVGNLNAFHLP
LSRSQSTTSSVQNNPPMSVRGDLDVSRPDSPSAQVTSEHVAGMAPPESIDIEPISNLGYSGDANAYNQAPATLPETPAAV
PAATIATTAPQPQQQQPLEETPLPQGAASSAGDYSIDDRLSSGTESYEMVPRADESTGSLVASEVPATTSVPPVSFTQSA
APTVPVSEQPSTETVTATSVPPVSFVSESSISVSTPVKPSEDASSSSAVPVAVAAAGAAVAAGTAAVIPTLDRVRSETSS
VDSKDVFKDARDFDSDDVNASASSQPKPIAQPSAPASSGTTISPIAEAPTQPATKNDDDGYSSSDDEGPEVLPGQPQFTG
PVAFRTSGNLAKASSFASASDIPIAAPIPKHAAAITESQNQQQQQSLSGPAAASTQSFTFVETPTPVSATASSHPFAAVA
QATGSEVGTPIPQSFSSTPVQNLAPQQPQQPQQPQQPQQQQQFDNNVFGTSVQSSTQSFPQTAPSTSRSVPLAFANQSSA
AQSTDDFSPFVAAPTTTQPADSFSPFNPQPESSQHHILPIKKPVDPFAAAFEGLEDAEEVNDESFKEIRGVPSQQPIQQE
FSQLAVKPFDFGNFSGPSASTGGFPSDPVDNFYNTPATAAVPQQQPQQQQQPAPQVNDEWDSLFANLSTSAPPTQSEVDY
AFGAPAQQQQQPPQQASQQEATAAFDSFVNSSLNTFSQNTSQAVAAAPAVAAAAPKITGPHAEELSQLVSMGFTQSEAYT
ALEKNKFNLESAINYLLEKPQH

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005509 calcium ion binding
GO:0005515 protein binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MIA_02098_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component