Protein

MIA_02092_1

Length
952 amino acids

Browser: contig02:2586772-2589631-

Protein function

EGGNOG:0PFSZMGM1mitochondrial dynamin GTPase
SGD closest match:S000005737MGM1Dynamin-like GTPase MGM1, mitochondrial
CGD closest match:CAL0000188111orf19.2690Dynamin-related GTPase

Protein alignments

%idAln lengthE-value
MCA_05975_174.63%8670.0MCA_05975_1
A0A0J9X956_GEOCN77.78%6930.0Similar to Saccharomyces cerevisiae YOR211C MGM1 Mitochondrial GTPase OS=Geotrichum candidum GN=BN980_GECA05s07039g PE=3 SV=1
A0A161HH50_9ASCO67.87%8280.0Dynamin-related GTPase MGM1 OS=Sugiyamaella lignohabitans GN=MGM1 PE=3 SV=1
A0A060T6Z0_BLAAD73.62%7090.0ARAD1C17468p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C17468g PE=3 SV=1
A0A1E3PQ36_9ASCO71.70%6890.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_69219 PE=3 SV=1
UniRef50_A0A1E3PQ3671.70%6890.0Uncharacterized protein n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PQ36_9ASCO
Q6C258_YARLI68.11%6930.0YALI0F10659p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F10659g PE=3 SV=1
A0A1E4TAT1_9ASCO59.92%7060.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_27617 PE=3 SV=1
Q5AFB7_CANAL57.34%7080.0Dynamin-related GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2690 PE=3 SV=1
MGM1_YEAST51.53%7180.0Dynamin-like GTPase MGM1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MGM1 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9992
Predicted cleavage: 108

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 800 900 952

Detailed signature matches

  1. Family IPR022812
    Dynamin superfamily
    1. PF00350 (Dynamin_N)
    2. PR00195 (DYNAMIN)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR001401
    Dynamin, GTPase domain
    1. SM00053 (dynamin_3)
  4. Domain IPR030381
    Dynamin-type guanine nucleotide-binding (G) domain
    1. PS51718 (G_DYNAMIN_2)
  5. Domain IPR000375
    Dynamin central domain
    1. PF01031 (Dynamin_M)
  6. Domain IPR020850
    GTPase effector domain
    1. PS51388 (GED)
  7. SITE IPR019762
    Dynamin, GTPase region, conserved site
    1. PS00410 (G_DYNAMIN_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd08771 (DLP_1)
  3. mobidb-lite (disord...)

Residue annotation

  1. G1 box cd08771
  2. GTP/Mg2+ binding s...
  3. homodimer interfac...
  4. G2 box cd08771
  5. Switch I region cd...
  6. G3 box cd08771
  7. Switch II region c...
  8. G4 box cd08771
  9. G5 box cd08771

Protein sequence

>MIA_02092_1
MPGISYLLSRRAAPAQAARAHAALNRAVLPRVSCARGPASHAISQQCTLHTGSTPRLGPVFFSSKGARASHRPRLTSSLF
SGLRPSAVVVARRGLSLGAATKLIVRAGAAAGGAVVGGAAYVNYKVQEVSSFTQDKISQASEWASDVLEGARDAVDGFDL
SGVSGFFGSLSKAASESLDKASDGSEAGSDNRGSSGGDGQSSGGNNNGDDGTGATAAVLGSAFAVGTDNNERNNAKEDQI
MLLTKKMIEIRNILKRVDQSETLQLPSIVVIGSQSSGKSSVLEAIVGHEFLPKGNNMVTRRPIELTLVNTPDSAAEYGEF
PSLGLGKITDFLQIQKTLTDLNLAVPDSDAVSDDPIQLNIYSPTVPDLTLIDLPGYIQVAANDQPESLKQKINILCEKYI
QPPNVILAISAADVDMANSAALKASRRADPRGERTIGVVTKMDLIDAHRGAELLNNKAYALQMGYVGVITKPPSGGLFRR
NSNIGALVTQNEQTYFSQFPEFDDADVGTSTLRRKLMNVLEKTMASSLQPTSEAIRQELEEAAYQFKVEYNDRILTPETY
LAGSVDSFKLAFKDLTTQFGRNEVRGLLKSELDQRVLDLLAQRYWNKPLEAPAQNSSVTSLKITEPALAELAGADPDNMY
WTRKLDASTSNLTKLGVGRLSTNLVINALMSEMDHLVDSTNFRNHPFARETIHDAASGILNMKFYSTADQVENCIKPYKY
EVDVEDREWAKSRDHAYNLLKEELRQCDNAYGQMKKAVGAHKLNQVIKFIEKTREAGVHGLPADESSDAFGFSQALLSRG
REALFLRDRSDTIRMRMTAIKSRQCKSKDNKYYCPEVFLDVVADKLTQTAVLFLNVELLSDFYYNFPRELDMRLGQHLTP
AQIEAFAKEDPKIRKHIELQQRRDLLKLALDKIESVIELEKNRVRDGSLSIPLPSSAQQLRQEAETRRRWGR

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

None predicted.