Protein

MIA_02087_1

Length
689 amino acids

Browser: contig02:2576442-2578512-

Protein function

EGGNOG:0QDPSFG08656.1WH1 domain
SGD closest match:S000005707LAS17Proline-rich protein LAS17
CGD closest match:CAL0000197581WAL1Actin-binding protein

Protein alignments

%idAln lengthE-value
A0A0J9XI08_GEOCN73.222%2392.53e-109Similar to Saccharomyces cerevisiae YOR181W LAS17 Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments OS=Geotrichum candidum GN=BN980_GECA19s01407g PE=4 SV=1
MCA_01173_170.082%2443.00e-107MCA_01173_1
A0A060TFJ3_BLAAD68.750%2405.54e-99ARAD1D23782p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D23782g PE=4 SV=1
A0A167CL39_9ASCO66.946%2391.42e-96Las17p OS=Sugiyamaella lignohabitans GN=LAS17 PE=4 SV=1
A0A1E3PQU4_9ASCO63.786%2434.57e-96WH1-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80945 PE=4 SV=1
UniRef50_A0A0H5C1A766.087%2302.62e-93Uncharacterized protein n=2 Tax=Cyberlindnera jadinii TaxID=4903 RepID=A0A0H5C1A7_CYBJA
Q6CDQ5_YARLI66.667%2282.64e-87YALI0B22110p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B22110g PE=4 SV=2
A0A1D8PU03_CANAL60.000%2353.21e-85Actin-binding protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=WAL1 PE=4 SV=1
LAS17_YEAST58.235%1701.13e-55Proline-rich protein LAS17 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LAS17 PE=1 SV=1
A0A1E4TJF3_9ASCO69.531%1289.94e-61Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_19420 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2998

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 689

Detailed signature matches

  1. Domain IPR011993
    PH domain-like
    1. G3DSA:2.30.29.30
    2. SSF50729 (PH domain...)
  2. Domain IPR000697
    WH1/EVH1 domain
    1. PS50229 (WH1)
    2. SM00461 (WH1_2)
    3. PF00568 (WH1)
  3. Domain IPR033927
    WASP family, EVH1 domain
    1. cd01205 (EVH1_WASP-...)
  4. Domain IPR003124
    WH2 domain
    1. PS51082 (WH2)
    2. PF02205 (WH2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Residue annotation

  1. WAS mutation hotsp...
  2. proline-rich pepti...

Protein sequence

>MIA_02087_1
MGLLTTADKEKIKRVIPKSTNKIVTVAVARLYIAYPDPQAWTYTGLSGALALVNDLVGNTFFFKLVDLGSSRGVLWDQEL
YVDFQYHQDRSFFHSFELETCYAGFLFADEGEAASFFKKVHHKEKHASKATLNNKNAIAAKKPKDQPQGPAAGTGLRGDT
AGNRQRVHLNTGVVYYDDEPPEEWRALYSELAAAGITEEMIADNREFIKNYIRQQGGPLVGLEPPIPRKAKERAYPAAIT
TNNSSTNNTYDDYESPAPLSPAESTSTFRRTRAPPPPPPSAGAPATAASSIAESDSDETRSSTPETRPPTSTGHKVPPPM
PYIGTHVPTVSAPQTPTSPQSAPPLPPAPAPAPTFASPVPPVLPSRTTNGPPLPPFPPQHPGLAPGLADRPLPAAPSLPP
RMPLSPGQDYTPRFGTPVSPYAQQPPPSLPQRTVGGGVPPPPPPPRAAGQSAAPPPPPPPRAGSAAVPPPPPSRASIATP
AAPAFPAYPTSPPPPPRIPQQQQYTPPVAAPVAPPLPPPLPQTAAPALPAAAAPPPPPLPSFAPPSVPSAAPPAPPLPPS
GPTSAPPPPPLPSSFQSSSGAPPAPPPPPPGGMPPAAAPPALPAVSGDRDALLASIRNAGIGSLRKVDKSALDKPSALLM
EAKGQAPPPAPSAAPGGQPASLADALAQALNKRKNKVGASDDEESDDGW

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003779 actin binding

Cellular Component

None predicted.