Protein

MIA_01981_1

Length
363 amino acids

Browser: contig02:2253277-2254369-

Protein function

EGGNOG:0PG90alcohol dehydrogenase
SGD closest match:S000000702ADH7NADP-dependent alcohol dehydrogenase 7
CGD closest match:CAL0000187810orf19.5517NADP-dependent alcohol dehydrogenase

Protein alignments

%idAln lengthE-value
MCA_04894_163.859%3681.69e-162MCA_04894_1
A0A1E4TMD6_9ASCO60.556%3602.52e-152Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_95529 PE=3 SV=1
UniRef50_W1Q6P655.742%3572.27e-115NADP-dependent alcohol dehydrogenase 7 n=19 Tax=Saccharomycetales TaxID=4892 RepID=W1Q6P6_OGAPD
ADH7_YEAST47.091%3612.43e-97NADP-dependent alcohol dehydrogenase 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH7 PE=1 SV=1
A0A1E3PTC8_9ASCO41.828%3618.28e-93GroES-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49175 PE=3 SV=1
A0A167CUK7_9ASCO39.892%3713.54e-75Adh6p OS=Sugiyamaella lignohabitans GN=ADH6 PE=3 SV=1
Q5AC33_CANAL39.227%3623.93e-75NADP-dependent alcohol dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5517 PE=3 SV=1
A0A060TEC7_BLAAD26.923%3644.42e-26ARAD1D06028p OS=Blastobotrys adeninivorans GN=AADH2 PE=3 SV=1
Q6C6P0_YARLI25.414%3628.42e-19YALI0E07766p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E07766g PE=3 SV=2
A0A0J9XBV1_GEOCN24.000%3255.76e-18Similar to Saccharomyces cerevisiae YMR083W ADH3 Mitochondrial alcohol dehydrogenase isozyme III OS=Geotrichum candidum GN=BN980_GECA07s02870g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0167

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 363

Detailed signature matches

  1. Domain IPR011032
    GroES-like
    1. SSF50129 (GroES-like)
  2. Domain IPR013154
    Alcohol dehydrogenase, N-terminal
    1. PF08240 (ADH_N)
  3. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  4. Domain IPR013149
    Alcohol dehydrogenase, C-terminal
    1. PF00107 (ADH_zinc_N)
  5. SITE IPR002328
    Alcohol dehydrogenase, zinc-type, conserved site
    1. PS00059 (ADH_ZINC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50.20
  2. G3DSA:3.90.18...
  3. cd05283 (CAD1)

Residue annotation

  1. catalytic Zn bindi...
  2. putative NAD(P) bi...
  3. putative substrate...
  4. structural Zn bind...
  5. dimer interface cd...

Protein sequence

>MIA_01981_1
MVYPETFQAVGVLDFDDYHNPKRFEYKPQAFRDYDVDIKIEACGVCYSDVHAASGNWGRLYTPIAVGHEIIGRIVKIGPN
AKPGLKLGDRVGVDAQCDCDSTCSACQEHTEQYCENSVATYLATYKESGLNTIGGNASHIRINSKLAFKIPDDLETVYAA
PLLCGGITGFSPLLKNNVKKGTKVGVVGIGGIGHMTILFAKALGAEVTAISRGKAKEADARKLGADHYIATSEPGSLEKS
ARTLDLIVSTSSSFSQTSLTPVIKLLKASGTFSFITAPPEKERMELIPIELISSGYAVQGSMIGSPENIEYMLDFASKHK
IKPWIETVEMNEENLGKIWKRMEDGDVRYRFTMVGYDKFFKDA

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.