Protein

MIA_01953_1

Length
1,994 amino acids


Browser: contig02:2177082-2183129-

Protein function

EGGNOG:0PHQ4STT4phosphatidylinositol 4-kinase
SGD closest match:S000004296STT4Phosphatidylinositol 4-kinase STT4
CGD closest match:CAL0000198621STT41-phosphatidylinositol 4-kinase

Protein alignments

%idAln lengthE-value
MCA_04627_157.590%20750.0MCA_04627_1
A0A0J9XF02_GEOCN57.892%19450.0Similar to Saccharomyces cerevisiae YLR305C STT4 Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway OS=Geotrichum candidum GN=BN980_GECA13s00802g PE=3 SV=1
UniRef50_A0A0J9XF0257.892%19450.0Similar to Saccharomyces cerevisiae YLR305C STT4 Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XF02_GEOCN
A0A167F2D2_9ASCO50.254%19720.01-phosphatidylinositol 4-kinase STT4 OS=Sugiyamaella lignohabitans GN=STT4 PE=3 SV=1
A0A060T3H5_BLAAD47.639%19480.0ARAD1C37422p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C37422g PE=3 SV=1
A0A1E3PIY6_9ASCO51.191%16370.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51982 PE=3 SV=1
Q6C4B9_YARLI49.520%17710.0YALI0E28153p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E28153g PE=3 SV=1
A0A1D8PTE0_CANAL42.883%16650.01-phosphatidylinositol 4-kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=STT4 PE=3 SV=1
STT4_YEAST43.377%15930.0Phosphatidylinositol 4-kinase STT4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STT4 PE=1 SV=1
A0A1E4TGW8_9ASCO38.706%16690.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_115283 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1562

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1400 1600 1800 1994

Detailed signature matches

    1. SSF48371 (ARM repeat)
    1. PF00613 (PI3Ka)
    2. SM00145 (pi3k_hr2_4)
    3. PS51545 (PIK_HELICAL)
    1. SSF56112 (Protein k...)
    1. PS50290 (PI3_4_KINA...)
    2. SM00146 (pi3k_hr1_6)
    3. PF00454 (PI3_PI4_ki...)
    1. PS00916 (PI3_4_KINA...)
    2. PS00915 (PI3_4_KINA...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd05167 (PI4Kc_III_...)
  2. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. catalytic loop cd0...
  3. activation loop (A...

Protein sequence

>MIA_01953_1
MDDFGIRRQGRGIRARAIENLVKLSTVSGEPSHIDRLVTVLSPSSSVYSPSDQEAADNPPLFLSELQVLISLSRSAHFIK
SPDQAESVLRLLGVYLRKSSALVFSAFSGVREIEPSPWHVATRLLTRAVLALGSNFPERLGSNAEGIILRYLNASIVKWK
DPATFNSPSVFCPLLFSFQGFLEALTQQALITSYGTLATVLSRLTEVITTELLLQIETTVAQITATTVEGVSFQDGSITP
RDTPRDTPPPQTASAPILGASTADEDISRWQYYFLSYLRAEQQLGAMLLNYYVCAFARAIVAKIITYTAPNAVTSFRARN
KTSSLLNKLLSRERMPSLKDHYSVQPNQDVNVDPSIKQILLSATANLALAQINSLDDGADYIELASPERIALAYATKVLA
IDIVGVATSYRILDVDTGSTIVTSSFLHEHGMSNPRLALAVFKLGAYLCTLDSETAGLIIRYFPHFISIPTVQTHLVRKC
AKALVYGLRTISQDVIVSTIYTLVNMVSTTVTRDSHSTGIQNGQAKTKEDPTAPTFVSDADSVKTSGYSLNMYRNAIAAI
VTITLVYDDPQISALAATVLNQKLNVSATELDREVAYGVAKLASYVPDKEFLSIFRSFQTLAIHAFQSNDHKMRTIVQEA
FCRISDSLTMEHPLYETYLSELLQSIVDRGDVQELEHHRPHVEISATANEIALYLPPLARLLPKPPKPHYKTGDKHINSL
FRDTWYNMVVHGFSQTSEWTQKFRTELEIIAHSTPPLVSPGSSNKIESDLELNTVLQRGSSHHNVNNQKEIMDSLASSHI
FDFKTLQYPKLMFLAATILLEGLRANTGNCSKILLYFGDPGIRSTGETNRYMRNIATDVTKAYLANVTRGHSPMFTSDQV
AFQVKKMLTLCCHRVSAIQQQAFECCEAIICTIPSSLCSEISLFTLLDLLSLLWKSCLDAETDEYEPRSTFTAAKSGVRI
ELSDSYDQRRESLRMLHSKAREWVRYALSFTSYDIKNILTSYMSGIENYSPSDSVVLGYTFALEMGGTVTVRDRELSVLN
HVNSNPLSTDTSAGFLSQYIWRREFHTTIASEVISKVTPNFYDQAAIRARKALVDVLAKTKAYHDYSHHHNQKYAGASSQ
QPPPTRPNFGETRALLFKASGYMGHPTEGKVIARLCVQIPMRAFTELSIQFGISLWTWAITEYPALKALIISEVAQLWEW
SVKEKLGLYTRRHDIVGPAYAKMEYAPTNKAEINYDAGLAVRDFGCHQKLIRYLSSSFQSIVFESKNYLKIFSRLLLTGL
QGLSHASLHPCARAGRFELIRFSLDVLEVLTRFGARIAYSFKHLVISAALTWFAQPAQWPFGGNKLTLKADMELLSGIAT
VIKSMYIGSSPGSSKQQGATLKSKRDVLLIFMNDELTKMTAWSDPLQLNSPHKDFVGSVTVQNVNEAWSIDPVLAVYLVE
RYAIQELVSRLQTLTSSQPSSVAHVPEALKYFITGTICTSVPRSSSSKNNSHYVIYWTPVSPIESINLFLPAYGGNSLLL
QYAMRSLESHDVNVTFFYVPQLVQTLRYDVFGYVERFILETANISQLFAHQIIWNILANLFKGEDLPEGQTEEDVINPTL
DRILERMISNFSPEDREFYEREFSFFNTVTSISKSLMPLLRKTKAEKKVKIDEEIAKIKVDVGVYLPSNPDGIVVDIDRK
AGRPLQSHAKTPFMATFKIQREIRDLHIDNDKNGNGNDNEEEDEEGQRTTTVQVWQSAIFKVGDDCRQDVMALQLISIFR
SIFNSSGLDLYVFPYRVTATAPGCGVIDVLPNSISRDMLGREAVNGLYEYFTTKFGGEDSIQFQQARNNFVKSLAAYSVI
SYLIQFKDRHNGNIMYDDQGHILHIDFGFCFDIVPGGVKFEAAPFKLTHEMVLVMGGSTSTQAYRWFEELAVKAFLASRP
HAETIIQAVLPMLDSGLPCFKGETTMRKLRARFALDRSERDAALYMRQLIKQSYESFFTKGYDEFQRLTNGIPY

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005488 binding
GO:0016301 kinase activity

Cellular Component

None predicted.