Protein
MIA_01884_1
Length
517 amino acids
Browser: contig02:1972522-1974228+
Protein function
| EGGNOG: | 0PHSH | PBN1 | Required for proper folding and or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity) |
|---|---|---|---|
| SGD closest match: | S000000557 | PBN1 | Protein PBN1 |
| CGD closest match: | CAL0000174087 | PBN1 | Protein PBN1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_05739_1 | 53.950% | 519 | 0.0 | MCA_05739_1 |
| A0A0J9XEZ7_GEOCN | 50.575% | 522 | 2.18e-170 | Similar to Saccharomyces cerevisiae YCL052C PBN1 Essential component of glycosylphosphatidylinositol-mannosyltransferase I OS=Geotrichum candidum GN=BN980_GECA13s00703g PE=4 SV=1 |
| UniRef50_A0A0J9XEZ7 | 50.575% | 522 | 4.46e-167 | Similar to Saccharomyces cerevisiae YCL052C PBN1 Essential component of glycosylphosphatidylinositol-mannosyltransferase I n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XEZ7_GEOCN |
| A0A060TBR2_BLAAD | 36.095% | 507 | 4.39e-83 | ARAD1B10516p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10516g PE=4 SV=1 |
| A0A1E3PDM2_9ASCO | 34.328% | 536 | 5.89e-83 | PIG-X-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47873 PE=4 SV=1 |
| A0A161HJJ0_9ASCO | 45.607% | 239 | 2.72e-66 | Pbn1p OS=Sugiyamaella lignohabitans GN=PBN1 PE=4 SV=1 |
| PBN1_YARLI | 25.947% | 528 | 8.51e-42 | Protein PBN1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=PBN1 PE=3 SV=1 |
| A0A1E4TFC5_9ASCO | 29.114% | 237 | 1.23e-18 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_106301 PE=4 SV=1 |
| PBN1_YEAST | 28.033% | 239 | 1.17e-13 | Protein PBN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PBN1 PE=1 SV=1 |
| PBN1_CANAL | 27.869% | 244 | 1.80e-13 | Protein PBN1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PBN1 PE=3 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0177
Protein family membership
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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-
TRANSMEMBRANE (Tran...)
Protein sequence
>MIA_01884_1 MSIRRRHTFFIQFDDPNAIEKFDFSQENASVLYSHFTSPREDKITVPYNLIASNSKLLSLLDSIDKLQVKWSRDVPFDHN YPAFIVREPGLHVEIVPKKSVSIDVENFSALLKTFFNVEFTGKKQFVNGFQWKSIYAPLDTLQPLSEALQNTLCEKSNTL CTFQLAELTYADSFSLTYGSLPSNARPINQESDLVFEVFWSNRTSIASDLDLTTSSISKLYPNEKVEVGLLAVHPEYTTK NSIWGLAGFSRDLDLNKTEKLLFQYTTKHRNTESSYYVDFVRPTGLHPKHEIHMSNVRVPQRGCALFAKYTFDKSLFLDK YQLKDLAEATPNRPPIGRLFGVWGETDLEAPVWAVGGWGSEALVQIYTATASDKLDLDFELPTHSRYEVPQQNASLVHEY QPWPVVFWACQSVSDKDGELEAKIPASIETKSIGYESIFPNDTVFYYFNPTIPNHFTSSHLQSEFDIPVAPFSSYSTVQV VSVVVIFTCFFYLLYEILRSFLGYNKPPTVDTNKKNS
GO term prediction
Biological Process
GO:0006506 GPI anchor biosynthetic process
Molecular Function
None predicted.
Cellular Component
GO:0005789 endoplasmic reticulum membrane