Protein

MIA_01750_1

Length
1,494 amino acids

Browser: contig02:1577611-1582157+

Protein function

EGGNOG:0PHFIYCS4Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity)
SGD closest match:S000004262YCS4Condensin complex subunit 1
CGD closest match:CAL0000201859YCS4Condensin complex subunit 1

Protein alignments

%idAln lengthE-value
MCA_04521_144.347%13620.0MCA_04521_1
A0A0J9XL18_GEOCN38.813%13140.0Condensin complex subunit 1 OS=Geotrichum candidum GN=BN980_GECA27s00340g PE=3 SV=1
UniRef50_A0A0J9XL1838.813%13140.0Condensin complex subunit 1 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XL18_GEOCN
A0A060T027_BLAAD35.901%13370.0Condensin complex subunit 1 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C09438g PE=3 SV=1
A0A167DNX7_9ASCO39.151%10830.0Ycs4p OS=Sugiyamaella lignohabitans GN=YCS4 PE=4 SV=1
A0A1E3PRG4_9ASCO34.415%13250.0Condensin complex subunit 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48672 PE=3 SV=1
A0A1D8PI01_CANAL31.937%13372.94e-166Condensin complex subunit 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YCS4 PE=3 SV=1
Q6C2N4_YARLI32.182%11876.00e-163Condensin complex subunit 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F06402g PE=3 SV=1
CND1_YEAST32.293%12171.12e-151Condensin complex subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YCS4 PE=1 SV=1
A0A1E4TMF1_9ASCO28.597%11262.98e-109Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_18181 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0277

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1494

Detailed signature matches

  1. Family IPR007673
    Condensin subunit 1
    1. PIRSF017127 (Conden...)
  2. Domain IPR024324
    Condensin complex subunit 1, N-terminal
    1. PF12922 (Cnd1_N)
  3. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  4. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
  5. Domain IPR032682
    Condensin complex subunit 1, C-terminal
    1. PF12717 (Cnd1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. NON_CYTOPLASM... (N...)
  4. TRANSMEMBRANE (Tran...)
  5. mobidb-lite (disord...)

Protein sequence

>MIA_01750_1
MHSDTFILSEILAEFQKNPSDVLENYSSLNIRESEIVSLLNEITDYLAVSADSINEENIFAGSLVVISRFGEFDREGQER
IVDLFTSVFNNQIIRASEVLTEEDQNTNGSHTQIHKFHESNSFHDTSNISLSIEEENHAEPIEINFASVIGEVKERISRY
GFLIYLLLNQLEESCQNEIKKITTSTQGSRRLAKKPETLAFMLKLIGISLVSTYQGLVSLSHSLPPQQSKLINRIFSTRV
ECSTFIGMVLKPVYRFMESDIILKNSNDKLFSILCLAVVEFDEIQNVQSCMGQLFLYFEHIAEPLGELLFTLYDKYKNTG
LYEEIVKYIISREFNPNDNKGPKAVALLIGRLVHLSPELVLKQFREICRLLDSKHYTLRSAVVEAAGIILYNLCKNAVIS
HTETSITEEEQEQELRSPSNAGFEKTLLDIKSLFDLLEERVLDINPYTRIRAIQALTNLTELNAKFNKRRPRMTELAVQS
LQDKSSLVRRNALRLLSRLISTHPFNYLNEDGRLNLSIWEEKLRAVQLELKKLDNDSNFEANTEIKNLENLGSTWKLKNT
VECVILENNEVSSSSQENPIADNPVVTKLQLALAYHTEAVGFIKKVHEGLVVALKLLNSKNKTETIESMDLFVLADAYGI
ETARSGVRLMIHLVWAKGGGNNDEALAIQKHLLSCYKSLFFDPPSDVSSIEANNIVARSLISLTYGATISEAASLERLLS
FAMEPSALVVSSQKLSLSTQLKQDATEPDHAITELVNKTIPTTCMISDDVINVLWKIYGYNQSMAKSQRRGAIIIIGMLA
KEKPSVISSVGLELLLRIGLGDLGRIDFKLAKYSCIALQRMINTSNNFRLKSASKKASDHSISEKKFCANHEVIRRLASF
IILPSVSMEWFSLCEEAINAVYSICDSPDIVLSHLIRLKTKQVFSPNHPSLEIEHRELGLNYLDIAKNIDGNSSLAQLLF
IVGHTSLKTLVYLENLEGQFKRRKIETERERAQEMEAKTSTSSHGPKLSRKEQEQEMTQEQEFNLIGGGTTEDDFSENLV
YIRETELMFGHHSLLSRFGPLISTLCLEIIRDIQNQEYSEANAHWERTAQVKLGVDFQSTQHNSPKRRHSKMLVVSATLS
LIKMMCVSSEFCSNNLSILVTILEHTSKLINPVIQSKYEIGDGYDAAHEDTSENNDSKNYSTKVINFEEIDDYNTAAIVR
SNIVLGMGDLAVQFNHELEDNMQFVYKRLRDHTKMVQRTTLLTLTFLILAGQVKAKDQQLLGQMARCLEDKDETIANLAH
IFFLELAAKDNAIYNNFIDMFNSLVSYTKKSEEMAKREGDDPDDVEYSISHASIRVDNNILRRSSRRSDINHNIPNQAYD
KYVEDSMVDINTDENAHKCNDAEDFESFEPLTREALHRILKFLVSLVDKERYIRQLSEKLAKRLEKCETPQMWDHLSYVL
SLLPHKNEEIADIISAGFKKNIPVITETVLRNNSEIEDFYDKQIDIQDENGIDI

GO term prediction

Biological Process

GO:0000278 mitotic cell cycle
GO:0030261 chromosome condensation

Molecular Function

GO:0005488 binding

Cellular Component

GO:0005634 nucleus