Protein

MIA_01744_1

Length
487 amino acids


Browser: contig02:1566433-1567957-

Protein function

EGGNOG:0PG3CHXK1hexokinase
SGD closest match:S000003222HXK2Hexokinase-2
CGD closest match:CAL0000189097HXK2Hexokinase-2

Protein alignments

%idAln lengthE-value
MCA_04697_182.195%4830.0MCA_04697_1
A0A060T772_BLAAD71.222%4830.0Phosphotransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C18788g PE=3 SV=1
A0A0J9XAY2_GEOCN71.721%4880.0Phosphotransferase OS=Geotrichum candidum GN=BN980_GECA07s03211g PE=3 SV=1
A0A1E4TDB2_9ASCO66.529%4840.0Phosphotransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26950 PE=3 SV=1
A0A167F8V8_9ASCO67.949%4680.0Phosphotransferase OS=Sugiyamaella lignohabitans GN=HXK2 PE=3 SV=1
F2Z672_YARLI62.998%5270.0Phosphotransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B22308g PE=3 SV=1
A0A1E3PLI5_9ASCO64.330%4850.0Phosphotransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_24715 PE=3 SV=1
UniRef50_W9CRL865.102%4900.0Phosphotransferase n=7 Tax=leotiomyceta TaxID=716546 RepID=W9CRL8_9HELO
HXKB_CANAL56.405%4840.0Hexokinase-2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HXK2 PE=1 SV=2
HXKB_YEAST56.818%4840.0Hexokinase-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HXK2 PE=1 SV=4

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1737
Predicted cleavage: 14

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 487

Detailed signature matches

    1. PS51748 (HEXOKINASE_2)
    1. PF00349 (Hexokinase_1)
    1. PF03727 (Hexokinase_2)
    1. PS00378 (HEXOKINASE_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PR00475 (HEXOKINASE)
  2. SSF53067 (Actin-lik...)
  3. cd00012 (NBD_sugar-...)

Residue annotation

  1. nucleotide binding...

Protein sequence

>MIA_01744_1
MVNLGPRKPPSRKGSMADVPKDLLNTISILEKKFIVDSEMLKKITDHFVEELCKGLSKEGGSIPMNITWVMDWPTGQEKG
AYMALDMGGTNFRVAEITLDGNRGFDVTQSKYLMPENLKTGSKDDLFDYIADCVGKFLSSSHPGEKIEDLFLGFTFSYPC
TQPAINRGILQTWTKGFDIAGVEGHDVAPMLESALRKKGLPISVTALINDTTGTLVASNYVDPQTKMGLIFGTGCNAAYY
ERFRNIPKLEGLLPNDQNISPDDYMAINCEWGAFDNEHKILPRTKWDIEIDDESPRPGQQCFEKMIAGYYLGEILRKVLC
DLYDEDTIFEGRDIKALRKPYSLDASFLSQIEEDPWENLTEVESLFLNKLGIFVTESERKLIRRLAELIGTRAARLSACG
VAAIIKQINMKSGHCGADGSVFNKYPNFKARMAEALAEIFDWPSKSYKSHPITVIPAEDGSGVGAALIAALTVNRINQGK
YIGQNDV

GO term prediction

Biological Process

GO:0001678 cellular glucose homeostasis
GO:0005975 carbohydrate metabolic process
GO:0006096 glycolytic process
GO:0046835 carbohydrate phosphorylation

Molecular Function

GO:0004396 hexokinase activity
GO:0005524 ATP binding
GO:0005536 glucose binding
GO:0016773 phosphotransferase activity, alcohol group as acceptor

Cellular Component

None predicted.