Protein

MIA_01737_1

Length
599 amino acids

Browser: contig02:1541566-1543366-

Protein function

EGGNOG:0PI52ATE1Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity)
SGD closest match:S000002985ATE1Arginyl-tRNA--protein transferase 1
CGD closest match:CAL0000192276orf19.2110Arginyltransferase

Protein alignments

%idAln lengthE-value
MCA_01467_143.498%6694.31e-161MCA_01467_1
UniRef50_I4Y5V630.170%4115.70e-44Uncharacterized protein (Fragment) n=2 Tax=Wallemia TaxID=148959 RepID=I4Y5V6_WALMC
A0A167G0C6_9ASCO38.191%1991.50e-38Ate1p OS=Sugiyamaella lignohabitans GN=ATE1 PE=4 SV=1
A0A060TCM9_BLAAD43.038%1581.47e-35ARAD1D44066p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D44066g PE=4 SV=1
A0A0J9X3G5_GEOCN48.125%1601.06e-33Arginyl-tRNA--protein transferase 1 OS=Geotrichum candidum GN=BN980_GECA01s09569g PE=3 SV=1
Q6C744_YARLI30.935%2782.82e-33Arginyl-tRNA--protein transferase 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E03894g PE=3 SV=1
A0A1E3PPN1_9ASCO33.333%2253.34e-30Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40437 PE=4 SV=1
A0A1E4TFY6_9ASCO36.410%1952.86e-31Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2400 PE=4 SV=1
A0A1D8PG12_CANAL41.379%1744.37e-29Arginyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2110 PE=4 SV=1
ATE1_YEAST38.922%1673.96e-24Arginyl-tRNA--protein transferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATE1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0591

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 599

Detailed signature matches

  1. Domain IPR007471
    Arginine-tRNA-protein transferase, N-terminal
    1. PF04376 (ATE_N)
  2. Domain IPR007472
    Arginine-tRNA-protein transferase, C-terminal
    1. PF04377 (ATE_C)
  3. Domain IPR016181
    Acyl-CoA N-acyltransferase
    1. SSF55729 (Acyl-CoA ...)

Protein sequence

>MIA_01737_1
MIQARVTPATSLVSLKISDQDFEKTPMLVRSAVKWADYMDNRHCGYCNGKSTSAISTERRGSALYSINVDNEPILLSEQL
EKDSAVSAVPVGVYSEMLNRGFRRSGTTFYKIDQRNSCCPQYTMRLIVSKFKPSRDHRKALNRFNRWVLGESESNLISIS
SSLYQNNDIDESMINLQTDKHSKTSLKKNKKQSEYNLPYNIHRIDADFDHFQKDIGDPNLELTPNDFSFETALSKQQKLK
KGQIKNTSEFKAMLHTCRPQFQISLKLSMATQEKFELYRKYQVAIHNDSFDEVTMSSFDGFLCRSPLNANSDLLDKDLSL
QDVKHLGGGTFHHEYRYMGKLIAFGVLDILPGNCISSVYLVWDPAYSELELGKVSVLREIVLTQDLQLPYYCLGLYVPSC
PKMHYKSSFQPTELLDPMSIPPSMLGYKNNLNKNDIHYMAAWEDVRWFPFQEFSTRWDTDGTHTDWYVSILEKKNLIPEQ
IKFKNPEVLGEPKRETQILGAENFPQFYVERTPIFDVFMPGIIPFESLIQALKTRFDMLSEMNICFKTDENSSKFIQLTS
KQLLNYKYYDFNSQFVEIILEFIAVVGIDLGPHFAFRLN

GO term prediction

Biological Process

GO:0016598 protein arginylation

Molecular Function

GO:0004057 arginyltransferase activity

Cellular Component

None predicted.