Protein

MIA_01732_1

Length
1,010 amino acids

Browser: contig02:1528952-1532615-

Protein function

EGGNOG:0PGKMAPE2Aminopeptidase
SGD closest match:S000001640APE2Aminopeptidase 2, mitochondrial
CGD closest match:CAL0000186164APE2Aminopeptidase 2

Protein alignments

%idAln lengthE-value
MCA_01370_180.045%8920.0MCA_01370_1
A0A060T249_BLAAD56.816%8730.0Aminopeptidase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A05016g PE=3 SV=1
A0A1E3PDX0_9ASCO55.205%8550.0Aminopeptidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84232 PE=3 SV=1
A0A1E4TFN6_9ASCO54.114%8630.0Aminopeptidase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57016 PE=3 SV=1
Q6CEL9_YARLI52.928%8880.0Aminopeptidase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B14641g PE=3 SV=2
UniRef50_Q6CEL952.928%8880.0Aminopeptidase n=3 Tax=Saccharomycetales TaxID=4892 RepID=Q6CEL9_YARLI
A0A167BY20_9ASCO60.494%7290.0Aminopeptidase OS=Sugiyamaella lignohabitans GN=AAP1 PE=3 SV=1
APE2_YEAST52.392%8780.0Aminopeptidase 2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APE2 PE=1 SV=4
APE2_CANAL50.504%8930.0Aminopeptidase 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APE2 PE=1 SV=3
A0A0J9X4K9_GEOCN40.516%8910.0Aminopeptidase OS=Geotrichum candidum GN=BN980_GECA03s00835g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3620
Predicted cleavage: 16

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 1010

Detailed signature matches

  1. Family IPR034016
    Aminopeptidase N-type
    1. cd09601 (M1_APN_2)
  2. Domain IPR014782
    Peptidase M1, membrane alanine aminopeptidase, N-terminal
    1. PR00756 (ALADIPTASE)
    2. PF01433 (Peptidase_M1)
  3. Domain IPR024571
    ERAP1-like C-terminal domain
    1. PF11838 (ERAP1_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.39...
  2. G3DSA:2.60.40...
  3. SSF55486 (Metallopr...)
  4. SSF63737 (Leukotrie...)

Residue annotation

  1. Zn binding site cd...

Protein sequence

>MIA_01732_1
MISTKRILAPGRSIDAVLRTRQAEASHIQYVLNRDLLLSSHRDTSRYFANITYHQISNQEVKGITYIKNSKISTPTTTNT
FSNTPTNSFINASLFTTPHNFFLNKPTYNKLRQQSRHYCSKHSSFLSTFHHSPSQMCYSADGASASSKIPERQLLPTNVK
PTNYNLTLNPNFETFKFDGDVAISLDIQETSSFITINSLEIDVIKTTLVVDGATPVEPVSTTFNKDDTTVTFEFKDEFKK
GSKAVLSIQYIGLLNDKLAGFYRSKYVDNGVTKYLATTQMEPADARRAFPGFDEPALKATYDITLIHDKNLTALSNMDVK
ETKSLENDKVATVFNTTPLMSSYLVAFIVGEFKYVESNLFRVPVRVYTTPGLESRAQFSADLGAKTLAFFEKTFDVEYPL
PKMDMIGIHDFSAGAMENWGLVTYRVVDLLFDEKNDSAATKQRVAEVVQHELAHQWFGDLVTMEWWDGLWLNEGFATWMS
WFSCNEFYPDWRVWETYVGDTLQSSLGLDALRSSHPIEVPVSKADEINQIFDAISYSKGSSVLKMLANYLGEENFIKGVS
DYLKLHKYGNTKTEDLWNALEKASGKNVASVMNTWTQKVGFPVVSVEENGDKITVTQNRFLNTGDPTPAEDETIYPINLA
LRTKDGIDESILLENRTATITVQDPSFFKLNGDQAGIYRVKYSPERVSKLAKAADLLSVEDRMGLVADARALASSGYSKT
SAFLELINGWKNESEPNVWDSVLGNYASVKRAWLFQPKEINEALKKLQASLVENKSLELGWTIKPDDGLLLQQLKANLYG
AAVGAEIPSFIDDALAKFKNYSSGNENAIDPNLRGAVFRAAGKYGGKEAFDKLLSIYHKKSSVEGLTAVRSLGYSTDKDL
RAKALSFTLDGTIRTQDVSYIFAPFSTTTESIEQVWSWFKENWDQLSEIYPASLGLLARVVGGASAGFSTKEQLADFEEF
FKNKDTKGYDQTLANTRDRLHAYISWTERDSKDVEDWLTSNGYLDRDAKL

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding

Cellular Component

None predicted.