Protein

MIA_01717_1

Length
514 amino acids


Browser: contig02:1492108-1493653-

Protein function

EGGNOG:0PH8NPGUG_00667Aminopeptidase
SGD closest match:S000001586APE1Vacuolar aminopeptidase 1
CGD closest match:CAL0000183019LAP41Metalloaminopeptidase

Protein alignments

%idAln lengthE-value
A0A0J9XE48_GEOCN72.23%4790.0Similar to Saccharomyces cerevisiae YKL103C LAP4 Vacuolar aminopeptidase yscI OS=Geotrichum candidum GN=BN980_GECA10s00868g PE=3 SV=1
MCA_01463_171.40%4860.0MCA_01463_1
A0A167C1H9_9ASCO63.25%5170.0Ape1p OS=Sugiyamaella lignohabitans GN=APE1 PE=3 SV=1
UniRef50_A0A167C1H963.25%5170.0Ape1p n=6 Tax=Saccharomycetales TaxID=4892 RepID=A0A167C1H9_9ASCO
A0A1E3PKU2_9ASCO65.55%4790.0Peptidase M18, aminopeptidase I OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83421 PE=3 SV=1
Q6CCD1_YARLI59.87%4660.0YALI0C10494p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C10494g PE=3 SV=1
A0A060SYZ4_BLAAD58.70%4600.0ARAD1C04708p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C04708g PE=3 SV=1
A0A1D8PJE0_CANAL53.62%4701e-176Metalloaminopeptidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LAP41 PE=3 SV=1
A0A1E4T9R6_9ASCO54.11%4756e-165Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29549 PE=3 SV=1
AMPL_YEAST50.32%4632e-155Vacuolar aminopeptidase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APE1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7818

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. PF02127 (Peptidase_M18)
    2. PR00932 (AMINO1PTASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF101821 (Aminopep...)
  2. SSF53187 (Zn-depend...)
  3. cd05658 (M18_DAP)

Residue annotation

  1. metal binding site...
  2. active site cd05658

Protein sequence

>MIA_01717_1
MAYSSTGRQNPSSIKAAAIVKTLKGSKDSNGDDWEDVDKYSPDLPFNPKYTPEGYTEKFLHFMNTSPTAYHAVDYLAKEL
EASGFKYLSERESWSEALNYKGKYYTTRNGSSLCAFVVGKNWLPGNGIGIIGAHIDALAAKLKPISKKEPVEGYAQIGVA
PYANSFAGPTWWDRDLGIGGKVIVREGKSVTSKLAHIPYPIARIPTLAPHFGALSVGPFNAETQMTPIIGLVGDDEKEDP
TDEEKLSPLYGKHSIKLLRAIAKNIGVEVKDLLQFDLELFDTQFGTVGGLQKDFLFCPRIDDKICSYCAIHALLDSLEDP
LSFPNDGLHMVALFDNEEVGSLSRQGARGGLLETVVDRILAYHSSDDELKRLTYANSFLVSADVIHAVNPNFANVYLDHH
KPKLNVGISLTCDPNGNMATNSVSIAFLEEIARQTGNTLQVFHIRNDSRSGGTIGPALSSATGIRAVDCGVPQLAMHSIR
ATTGSKDVWLGVKMFKAFFEKWKEVDVQFKLGDL

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004177 aminopeptidase activity
GO:0008270 zinc ion binding

Cellular Component

None predicted.