Protein

MIA_01684_1

Length
469 amino acids

Browser: contig02:1388216-1389626+

Protein function

EGGNOG:0PFW6PEPPCatalyzes the removal of a penultimate prolyl residue from the N-termini of peptides (By similarity)
SGD closest match:S000001902YFR006WUncharacterized peptidase YFR006W
CGD closest match:CAL0000180447orf19.7263Putative Xaa-Pro dipeptidase

Protein alignments

%idAln lengthE-value
MCA_01063_173.402%4850.0MCA_01063_1
A0A0J9XC47_GEOCN65.532%4700.0Similar to Saccharomyces cerevisiae YFR006W Putative X-Pro aminopeptidase OS=Geotrichum candidum GN=BN980_GECA07s04256g PE=3 SV=1
A0A060T594_BLAAD63.326%4690.0ARAD1B08910p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B08910g PE=3 SV=1
A0A167FRM0_9ASCO60.504%4760.0Putative Xaa-Pro dipeptidase OS=Sugiyamaella lignohabitans GN=AWJ20_3251 PE=3 SV=1
A0A1E3PH99_9ASCO56.962%4740.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52412 PE=3 SV=1
Q6C610_YARLI58.503%4413.87e-176YALI0E13464p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E13464g PE=3 SV=1
A0A1D8PFY5_CANAL55.435%4601.19e-170Putative Xaa-Pro dipeptidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7263 PE=3 SV=1
UniRef50_B9WMB953.548%4651.76e-166Peptidase, putative n=23 Tax=Saccharomycetales TaxID=4892 RepID=B9WMB9_CANDC
A0A1E4TAQ8_9ASCO54.506%4661.11e-166Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28801 PE=3 SV=1
YFH6_YEAST49.370%4761.80e-157Uncharacterized peptidase YFR006W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YFR006W PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8807
Predicted cleavage: 28

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 469

Detailed signature matches

  1. Domain IPR029149
    Creatinase/Aminopeptidase P/Spt16, N-terminal
    1. G3DSA:3.40.35...
  2. Domain IPR028980
    Creatinase/Aminopeptidase P, N-terminal
    1. SSF53092 (Creatinas...)
  3. Domain IPR007865
    Aminopeptidase P, N-terminal
    1. PF05195 (AMP_N)
    2. SM01011 (AMP_N_2)
  4. Domain IPR000994
    Peptidase M24
    1. SSF55920 (Creatinas...)
    2. PF00557 (Peptidase_M24)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.90.23...
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. cd01087 (Prolidase)

Residue annotation

  1. active site cd01087

Protein sequence

>MIA_01684_1
MSKYPAKNHARKTLSYYRSLVAAAAANASDKPLFALTAPSLTLYPHCDQTQPFRQDRYFNYLTGAHDLPAAAVLYNSAAD
RLTLYLPPIDADDVMWSGLPLSPTQAKEKYDFDAVKYYADLAEDVASTDVLTIDDRNKTVLESLLSSSTVTVSPTFKEAL
EEARLRKDDFELALMRRASAISDVSHRAVMSALPIETNEGHIHAEFVYHSMRQGSKFQSYDPICCSGTDCGTLHYVRNDQ
EMADKQLVLIDAGAEWQCYASDVTRVFPITGEWTPEALAIYKAVLDMQTQCMEGVKPGVPWDDLHLLSHRILIKHFIELG
IFKKTKSPEEILEARTSVGFLPHGLGHLLGMDTHDVAGHPNYEDPDPMFRYLRLRRPLEPGFVVTVEPGIYFNKFLLEPY
LKDPKHLEIIDTEVLEKYWAVGGVRLEDDVLVTETGFENFTKVTTDPEEVSRIVKEGIAKGRSHFHVLA

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0004177 aminopeptidase activity
GO:0030145 manganese ion binding

Cellular Component

None predicted.