Protein

MIA_01668_1

Length
509 amino acids

Browser: contig02:1347607-1349441+

Protein function

EGGNOG:0PI53VMA2vacuolar atp synthase subunit b
SGD closest match:S000000331VMA2V-type proton ATPase subunit B
CGD closest match:CAL0000199755VMA2V-type proton ATPase subunit B

Protein alignments

%idAln lengthE-value
MCA_00323_195.331%5140.0MCA_00323_1
A0A0J9XIV8_GEOCN94.499%5090.0Similar to Saccharomyces cerevisiae YBR127C VMA2 Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) OS=Geotrichum candidum GN=BN980_GECA17s02144g PE=3 SV=1
A0A1E3PU76_9ASCO89.903%5150.0Vacuolar ATP synthase subunit B OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49150 PE=3 SV=1
A0A167FIB1_9ASCO92.944%4960.0H(+)-transporting V1 sector ATPase subunit B OS=Sugiyamaella lignohabitans GN=VMA2 PE=3 SV=1
A0A060T3V8_BLAAD89.147%5160.0ARAD1C43252p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C43252g PE=3 SV=1
UniRef50_P1614088.738%5150.0V-type proton ATPase subunit B n=965 Tax=Eukaryota TaxID=2759 RepID=VATB_YEAST
VATB_YEAST88.738%5150.0V-type proton ATPase subunit B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VMA2 PE=1 SV=2
Q6C4E9_YARLI88.867%5120.0YALI0E27346p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E27346g PE=3 SV=1
VATB_CANAL92.165%4850.0V-type proton ATPase subunit B OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VMA2 PE=3 SV=1
A0A1E4TAN6_9ASCO87.652%4940.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3436 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1150

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 509

Detailed signature matches

  1. Family IPR022879
    V-type ATP synthase regulatory subunit B/beta
    1. MF_00310 (ATP_synth...)
    2. PIRSF039114 (V-ATPs...)
  2. Family IPR005723
    ATPase, V1 complex, subunit B
    1. TIGR01040
  3. Domain IPR004100
    ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain
    1. PF02874 (ATP-synt_ab_N)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR000194
    ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
    1. PF00006 (ATP-synt_ab)
  6. Domain IPR024034
    ATPase, F1/V1 complex, beta/alpha subunit, C-terminal
    1. G3DSA:1.10.11...
  7. SITE IPR020003
    ATPase, alpha/beta subunit, nucleotide-binding domain, active site
    1. PS00152 (ATPASE_ALP...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd01135 (V_A-ATPase_B)

Residue annotation

  1. Walker A motif hom...
  2. Walker B motif cd0...

Protein sequence

>MIA_01668_1
MASARLSDKELFELNAKAVTQGFNIAPRLDYNTVGGVNGPLVILENVKFPRFNEIVNLTLPDGSSRAGQVLEVRGDRAIV
QVFEGTSGIDVKKTHVEFTGQNLKIPVSEDVLGRIFDGSGRPIDNGPKVLAEDYLDINGSPINPYSRIYPEEMISTGISA
IDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETSRFFKQDFEENGSLER
VSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMTSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYE
RAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRPLHNRGIYPPINVLPSLSRLMKSAIGEGMTRKDHG
DVSNQLYAKYAIGRDAAAMKAVVGEEALSNEDKLSLEFLEKFENTFIAQGAYEDRTIFESLDQAWSLLRIYPKEYLNRIS
PKILEEFYERERSTKDTVDGTPEENLIDA

GO term prediction

Biological Process

GO:0015991 ATP hydrolysis coupled proton transport
GO:0015992 proton transport
GO:0046034 ATP metabolic process

Molecular Function

GO:0005524 ATP binding
GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances

Cellular Component

GO:0033180 proton-transporting V-type ATPase, V1 domain