Protein

MIA_01560_1

Length
603 amino acids

Browser: contig02:1074443-1076311+

Protein function

EGGNOG:0PFWSCALNEXINCalnexin
SGD closest match:S000000054CNE1Calnexin homolog
CGD closest match:CAL0000187566orf19.5300Calnexin

Protein alignments

%idAln lengthE-value
MCA_03281_179.618%4710.0MCA_03281_1
A0A0J9XKH9_GEOCN74.034%4660.0Similar to Saccharomyces cerevisiae YAL058W CNE1 Calnexin integral membrane ER chaperone involved in folding and quality control of glycoproteins OS=Geotrichum candidum GN=BN980_GECA27s00549g PE=3 SV=1
A0A060SYI0_BLAAD67.521%4680.0ARAD1A16720p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A16720g PE=3 SV=1
A0A167CNI7_9ASCO65.447%4920.0Calnexin OS=Sugiyamaella lignohabitans GN=CNE1 PE=3 SV=1
UniRef50_A0A167CNI765.447%4920.0Calnexin n=10 Tax=Saccharomycetales TaxID=4892 RepID=A0A167CNI7_9ASCO
A0A1E3PK87_9ASCO58.542%4800.0Calnexin OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82800 PE=3 SV=1
Q6CET3_YARLI60.164%4870.0YALI0B13156p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B13156g PE=3 SV=1
A0A1E4TK06_9ASCO55.769%4681.16e-171Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_47571 PE=3 SV=1
A0A1D8PM03_CANAL47.619%4838.07e-119Calnexin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5300 PE=3 SV=1
CALX_YEAST35.980%4033.43e-66Calnexin homolog OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CNE1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4725

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 603

Detailed signature matches

  1. Family IPR001580
    Calreticulin/calnexin
    1. PF00262 (Calreticulin)
    2. PR00626 (CALRETICULIN)
  2. Domain IPR013320
    Concanavalin A-like lectin/glucanase domain
    1. SSF49899 (Concanava...)
  3. Domain IPR009033
    Calreticulin/calnexin, P domain
    1. SSF63887 (P-domain ...)
  4. SITE IPR018124
    Calreticulin/calnexin, conserved site
    1. PS00804 (CALRETICUL...)
    2. PS00805 (CALRETICUL...)
    3. PS00803 (CALRETICUL...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. G3DSA:2.60.12...
  4. NON_CYTOPLASM... (N...)
  5. SIGNAL_PEPTIDE (Sig...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SIGNAL_PEPTID... (S...)
  9. SignalP-noTM
  10. TMhelix
  11. TRANSMEMBRANE (Tran...)
  12. mobidb-lite (disord...)

Protein sequence

>MIA_01560_1
MKFSQLALSALVAASSVKATIDIDQDVNFEDIVAPKAGSNKFAAKATRPKEEKPKIEHPPFEPLPAPKGALFFEQFTDDT
AGRWKASNAVKAGTDGEFSYVGKWAIEEPTVFPGFKGDKGLVVKSPAAHHAISAKFDKPIDNKDNTLVVQYEVKLQKTLE
CGGAYIKLLSENEKLHAEEFSNDTPYQVMFGPDKCGSTNKVHFIIRRKNPKTGEYEEKHLKNPPPARLNNLTNLYTLIIK
PTQDFEIRINGKVVRAGNLLDEGVLLPSLSPPKEVDDPNDTKPEDWVDDVTIPDPEQATKPEDWDEDAPAKIPDPKSAKP
ADWDEDTPLYIPDPDAQKPEDWDDEEDGEFVAPEIENPECATHGCGPWKAPLVPNPDYKGKWVQPRIPNPDYKGEWAPKL
IPNPDYYEDKTPSDLEPIGAVGIELWTMQNNILFDNFYFGHSVDEAEFVGNQTFVPKVTIEQAEETAKAESIKPKDDKPR
KSYPTRLDHFKDDPVDFVVETARHFILNFSLDPIETIKADPLVFLAFVASGFTLFAVFFGILGAIGFLFKSLIFGSSKKP
AAADKKKVEAAEKKEEVEKNEEASTSSKATETTAVKRATKDEE

GO term prediction

Biological Process

GO:0006457 protein folding

Molecular Function

GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0051082 unfolded protein binding

Cellular Component

GO:0005783 endoplasmic reticulum