Protein

MIA_01558_1

Length
265 amino acids

Browser: contig02:1071180-1072041+

Protein function

EGGNOG:0PJMDPGUG_00082ribonuclease H
SGD closest match:S000004847RNH1Ribonuclease H
CGD closest match:CAL0000184579orf19.5564Uncharacterized protein

Protein alignments

%idAln lengthE-value
MCA_05772_257.823%1471.67e-45MCA_05772_2
A0A161HJH2_9ASCO40.078%2579.24e-45Ribonuclease H OS=Sugiyamaella lignohabitans GN=RNH1 PE=3 SV=1
UniRef50_A0A161HJH240.078%2572.54e-41Ribonuclease H n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A161HJH2_9ASCO
A0A1E3PU38_9ASCO50.595%1682.18e-38Ribonuclease H OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49110 PE=3 SV=1
Q6CHD9_YARLI39.841%2511.68e-36Ribonuclease H OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A09878g PE=3 SV=1
A0A0J9X3A6_GEOCN47.590%1662.98e-32Ribonuclease H OS=Geotrichum candidum GN=BN980_GECA01s10097g PE=3 SV=1
A0A060TD98_BLAAD50.000%1582.00e-30Ribonuclease H OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D41536g PE=3 SV=1
A0A1D8PQ03_CANAL42.857%1681.11e-24Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5564 PE=4 SV=1
RNH1_YEAST33.690%1875.40e-14Ribonuclease H OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RNH1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2565

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 265

Detailed signature matches

  1. Family IPR017067
    Ribonuclease H1, eukaryote
    1. PIRSF036852 (RNase_...)
  2. Domain IPR009027
    Ribosomal protein L9/RNase H1, N-terminal
    1. SSF55658 (L9 N-doma...)
  3. Domain IPR011320
    Ribonuclease H1, N-terminal
    1. PF01693 (Cauli_VI)
    2. G3DSA:3.40.97...
  4. Domain IPR012337
    Ribonuclease H-like domain
    1. SSF53098 (Ribonucle...)
    2. G3DSA:3.30.42...
  5. Domain IPR002156
    Ribonuclease H domain
    1. PF00075 (RNase_H)
    2. PS50879 (RNASE_H)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd09280 (RNase_HI_e...)
  2. mobidb-lite (disord...)

Residue annotation

  1. active site cd09280
  2. RNA/DNA hybrid bin...

Protein sequence

>MIA_01558_1
MAKKKFYVVVKGFKPGIYDTWDEAKKNVDGFRGNKHKAFPSRAEAETYFKQEIASGKHTNPHSSISSVRSSGHITKDNNV
KKKTSLKSFELALTDDGADAIIKSCPDTPKQRTIDVYTDGSTLGNGQRGARAGYGVYYGINDPRNVSKRLPGTPQTNQRA
ELSAVNEALEQILKDLPDRARIYTDSQYTIKCLTVWGVNWEKKGYKTANGGPVQNEDLIRLGIHLFEKLRAKGVDIQFYY
VPGHKGHHGNEEADRLARYGASLDS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

Cellular Component

None predicted.