Protein

MIA_01519_1

Length
562 amino acids

Browser: contig02:951271-952960+

Protein function

EGGNOG:0PFU0CPYAVacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity)
SGD closest match:S000000343YBR139WPutative serine carboxypeptidase YBR139W
CGD closest match:CAL0000190176PRC3Carboxypeptidase

Protein alignments

%idAln lengthE-value
MCA_01073_166.111%5400.0MCA_01073_1
A0A167C8Y8_9ASCO54.525%4422.99e-164Carboxypeptidase OS=Sugiyamaella lignohabitans GN=PRC1 PE=3 SV=1
A0A0J9XJ85_GEOCN54.730%4441.11e-162Carboxypeptidase OS=Geotrichum candidum GN=BN980_GECA24s00472g PE=3 SV=1
UniRef50_P3810952.184%4352.66e-158Putative serine carboxypeptidase YBR139W n=21 Tax=Saccharomycetales TaxID=4892 RepID=YBY9_YEAST
YBY9_YEAST52.184%4351.11e-161Putative serine carboxypeptidase YBR139W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YBR139W PE=1 SV=1
A0A1E3PJW0_9ASCO53.515%4411.02e-159Carboxypeptidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52072 PE=3 SV=1
A0A1D8PDM9_CANAL52.715%4421.59e-158Carboxypeptidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRC3 PE=3 SV=1
A0A060T003_BLAAD51.818%4408.16e-156Carboxypeptidase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C04554g PE=3 SV=1
Q6CG27_YARLI45.144%5565.34e-153Carboxypeptidase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B01408g PE=3 SV=1
A0A1E4TGJ1_9ASCO49.888%4472.47e-142Carboxypeptidase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31721 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1359

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 562

Detailed signature matches

  1. Family IPR001563
    Peptidase S10, serine carboxypeptidase
    1. PF00450 (Peptidase_S10)
    2. PR00724 (CRBOXYPTASEC)
  2. Domain IPR029058
    Alpha/Beta hydrolase fold
    1. SSF53474 (alpha/bet...)
    2. G3DSA:3.40.50...
  3. SITE IPR018202
    Serine carboxypeptidase, serine active site
    1. PS00131 (CARBOXYPEP...)
  4. SITE IPR033124
    Serine carboxypeptidases, histidine active site
    1. PS00560 (CARBOXYPEP...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. NON_CYTOPLASM... (N...)
  2. SIGNAL_PEPTIDE (Sig...)
  3. SIGNAL_PEPTID... (S...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SignalP-noTM

Protein sequence

>MIA_01519_1
MKLSAKSLAVLAASVSATNAFNLLDIPQNLLGAFDNLVASGFAMTPVTPQLADAAHDLGINPKWLPDSIRKYWKDVASDV
DSNSKKPQSAFRRVKKVFLSDESKKSKDRKKQRVSRRTDFDLHVKSEKFPMHALRVKTNTAESLGLDSVKQYTGYFDVDG
PEDDSGKHLFFWFFESRNDPTKDPVLVWLNGGPGCSSLMGMLYELGPSNILTPVEKPELNPYSWNNNASVIFLDQPAGVG
FSYFDSENVPVSDTRASAADVYAFLSLFFQQFPEYKDLGLNIAGESYAGHYIPAISTEILKHPDRNFVFKSVLIGNGWTD
TYHQSAGYGPMACGKGGYKPVLSEEQCAKFNHTEARCRWLDGLCYKRQDRLTCVPATYVCDSLLDPYIDTGLNPYDIRKP
CVGSQDMCYDDIDYYANYLNKPKVQAAIGAEVENYEGCSDPVFNAFIHTGDGGKPFHFDVVDALAQGLEVLVYAGDKDYI
CNWVGQVKWLDALEWPGADEWAEGKFAPWATVVDGEAAGEYKKAGNLTFVRVYDAGHMVPYDQPKHALDMVTRWLHGGRS
FA

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004185 serine-type carboxypeptidase activity

Cellular Component

None predicted.