Protein

MIA_01307_1

Length
416 amino acids

Browser: contig02:304887-306138-

Protein function

EGGNOG:0PGPEFG07180.1Disulfide-isomerase
SGD closest match:S000000548PDI1Protein disulfide-isomerase
CGD closest match:CAL0000202048orf19.2516Uncharacterized protein

Protein alignments

%idAln lengthE-value
MCA_00191_165.56%3633e-169MCA_00191_1
A0A0J9XCV3_GEOCN52.07%3637e-126Similar to Saccharomyces cerevisiae YCL043C PDI1 Protein disulfide isomerase OS=Geotrichum candidum GN=BN980_GECA09s04234g PE=3 SV=1
UniRef50_A0A0J9XCV352.07%3631e-122Similar to Saccharomyces cerevisiae YCL043C PDI1 Protein disulfide isomerase n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCV3_GEOCN
A0A167EI20_9ASCO42.54%3552e-95Protein disulfide isomerase PDI1 OS=Sugiyamaella lignohabitans GN=PDI1 PE=4 SV=1
A0A060TBK0_BLAAD38.61%3601e-78ARAD1B16324p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B16324g PE=4 SV=1
Q6CC54_YARLI38.19%3646e-76YALI0C12386p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C12386g PE=3 SV=1
A0A1E4TJ40_9ASCO31.79%3904e-66Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30104 PE=4 SV=1
A0A1E3PTP3_9ASCO29.92%3812e-57Thioredoxin-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_19354 PE=4 SV=1
A0A1D8PJ36_CANAL30.40%2274e-26Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2516 PE=4 SV=1
PDI_YEAST39.09%1102e-16Protein disulfide-isomerase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PDI1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0934

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 416

Detailed signature matches

  1. Domain IPR012336
    Thioredoxin-like fold
    1. SSF52833 (Thioredox...)
  2. Domain IPR013766
    Thioredoxin domain
    1. PF00085 (Thioredoxin)
    2. PS51352 (THIOREDOXIN_2)
  3. Domain IPR011679
    Endoplasmic reticulum resident protein 29, C-terminal
    1. G3DSA:1.20.11...
    2. SSF47933 (ERP29 C d...)
    3. PF07749 (ERp29)
  4. SITE IPR017937
    Thioredoxin, conserved site
    1. PS00194 (THIOREDOXIN_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.30.10
  3. NON_CYTOPLASM... (N...)
  4. PR00421 (THIOREDOXIN)
  5. PS51257 (PROKAR_LIP...)
  6. SFLDG00345 (PDI-like)
  7. SIGNAL_PEPTIDE (Sig...)
  8. SIGNAL_PEPTID... (S...)
  9. SIGNAL_PEPTID... (S...)
  10. SIGNAL_PEPTID... (S...)
  11. SignalP-noTM
  12. TMhelix
  13. mobidb-lite (disord...)

Protein sequence

>MIA_01307_1
MKVFGGIISLFLFACVAIASNVIELTDKNFKSVVLDSKIPTIVDIYASWCGHCKRLNPIYEELADAFSHAKDKIQVVKID
GDVHRQTAKKFKVEGFPTIKFISADGSEEDVNVARDLDALANFITEKTGIQRKFTNVAPSAVLSLTDANFEEFISDDGKT
AIVAFTASWCGHCKSLKPIYKELAEVFVNDDEVIIAEVDTTGGEAEEITAKFGIRSYPTILIFNKEYEKPVQYKEARSLE
AMTNRLNQLAGTGRNPDGSLNEYAGRFKKLDRLSRQFLDAEKASRGFIKEKIVQFMANAQKDGQKAALNASKLYLRFAEK
IEESEAYLEKEVKRLTNIISRGGLKKSKLDEMSKKLNILRTFVPGHVAEADVAEEVKEVPEKEVKEDVKEEVKEEVKEEV
KEEVKEEKKEEKKDEL

GO term prediction

Biological Process

GO:0045454 cell redox homeostasis

Molecular Function

None predicted.

Cellular Component

GO:0005783 endoplasmic reticulum