Protein

MIA_01022_1

Length
1,139 amino acids

Browser: contig01:2928833-2932253+

Protein function

EGGNOG:0PGKQPGUG_00090RhoGAP and Fes CIP4 domain protein
SGD closest match:S000001847RGD2Rho-GTPase-activating protein RGD2
CGD closest match:CAL0000176620RGD3Rgd3p

Protein alignments

%idAln lengthE-value
MCA_00788_145.100%10000.0MCA_00788_1
A0A0J9XJ53_GEOCN36.589%6451.01e-107Similar to Saccharomyces cerevisiae YFL047W RGD2 GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p OS=Geotrichum candidum GN=BN980_GECA20s01297g PE=4 SV=1
UniRef50_A0A0J9XJ5336.589%6452.06e-104Similar to Saccharomyces cerevisiae YFL047W RGD2 GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJ53_GEOCN
A0A060T6A9_BLAAD28.682%3871.20e-54ARAD1B10450p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10450g PE=4 SV=1
A0A170R0A7_9ASCO32.338%4026.82e-54Rgd2p OS=Sugiyamaella lignohabitans GN=RGD2 PE=4 SV=1
A0A1E3PDI3_9ASCO32.216%3889.60e-53Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80294 PE=4 SV=1
Q6C6X5_YARLI29.977%4272.12e-52YALI0E05489p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E05489g PE=4 SV=1
A0A1D8PTI9_CANAL27.990%3936.07e-36Rgd3p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RGD3 PE=4 SV=1
RGD2_YEAST23.636%4401.38e-27Rho-GTPase-activating protein RGD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RGD2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0103

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1139

Detailed signature matches

  1. Domain IPR027267
    Arfaptin homology (AH) domain/BAR domain
    1. SSF103657 (BAR/IMD ...)
  2. Domain IPR031160
    F-BAR domain
    1. PS51741 (F_BAR)
  3. Domain IPR001060
    FCH domain
    1. SM00055 (fch_2)
  4. Domain IPR011991
    Winged helix-turn-helix DNA-binding domain
    1. G3DSA:1.10.10.10
    2. SSF46785 ("Winged h...)
  5. Domain IPR000591
    DEP domain
    1. PF00610 (DEP)
    2. PS50186 (DEP)
  6. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
  7. Domain IPR000198
    Rho GTPase-activating protein domain
    1. SM00324 (RhoGAP_3)
    2. PF00620 (RhoGAP)
    3. PS50238 (RHOGAP)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.55...
  3. mobidb-lite (disord...)

Protein sequence

>MIA_01022_1
MSDHSEPPAAGPPATTLNGENPVSDSQNEHQQSEQQEQQHQALDTPQVPSKLHQEFTDCFWSSDYATGLNVLFDKLDQGV
TENAQILDFISRRISLESAYAANLKSSSDNVMTSRQAAFGFDRDEGASAKQAFVAFLDESSTQGELHSRIAAGLERQVRE
PFSHYADEHKLRVSKTRSTILSNLKSYNKSLDNVHRAQQNYYAKARQLEELTNSSVPVMVASGGVVNNAPTRSLSMAISS
SASAINKRLSLAQFSKVAEPAIPEAAEPSSSATKEDVKGKSITKQPNVKEDNTVKPPTISAEATAATNTTTNNSVDPAAP
TPQDAPTRTASYPRQNSLSDEIVIFGGRSFTPKNLQELLQDFLNTVPQETFKIRFIATYPNVSTGEAILHYIRINVGINN
IGIAEKFGQDMVDQGFLRLVGAVGSRFSGTSNSRYQWLPRAIEFAKNGFYHQSSTGEKLSEIQNTVIAEEQTAADAASAF
AKKTSNMVSGYFSSLLATTEEEPGSEANNDSTTPPVHKRHESMSILSSLSRADSFPGKFHSRTASSADLGSASQPPLPRR
ESQISKLQREISELDEKYQIASRNLDDERCNLELQIFELYPFMQQCERDRLRAVKKVLLDFTAGIGRTLNNLHQSVQRMA
FHESLLDPIKDLDYLIERYKTGPFAPKPVVYMGFYKSYRIQSFGVDLKFVPFVVEDFISYISDEKNVTGETKETVAEITE
FPSISTGGNSYKSRLTSDASRDILIGLWTQHQAPIDEIQALRRKINTAKKFNPDDAFKGYTLPIVVSTLREFLLELPDSI
ISSTVYDVIKTAYTKSGPKANIVLEMTPEEKKEVEINNAEQRVERLVGLLTHLERENLSNLKVLISHFADICRVSSESTS
LKAVLQEDIPENVKNLSQRIAPYLLKPRAITSLTLTDKHPVQLIQDLIIYRDVIFSQVEARLEKAQKNRRRSRSASGSEA
NRRFHIEERNKAIAAAHGINNNGSITPSHSSSSLAAVISGGSSNGSSPPKISGPLPLTLSSGVRSRHSVTNSDASDEGRG
DEGSADGPYGELTSGATLRPGRPLAHRRTPSGNKLSIRSFLEPGGGISRSSTPTPGSQGAGENSSAPLTTEAPALVPPTI
SVTDASEVESALANRDTQN

GO term prediction

Biological Process

GO:0007165 signal transduction
GO:0035556 intracellular signal transduction

Molecular Function

None predicted.

Cellular Component

None predicted.