MIA_01019_1

Protein

Length

587 amino acids

Protein function

EGGNOG:	0QDJB	PGUG_05050	transporter
SGD closest match:	S000001428	YIL166C	Uncharacterized transporter YIL166C
CGD closest match:	CAL0000201100	orf19.6520	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
A0A0J9X6U0_GEOCN	62.413%	572	0.0	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA04s01770g PE=4 SV=1
A0A167D9I1_9ASCO	57.790%	552	0.0	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_906 PE=4 SV=1
A0A1E3PQH2_9ASCO	60.388%	515	0.0	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_19598 PE=4 SV=1
UniRef50_A0A100I8Y7	60.800%	500	0.0	FAD/FMN-containing dehydrogenase n=1 Tax=Aspergillus niger TaxID=5061 RepID=A0A100I8Y7_ASPNG
A0A1D8PQZ7_CANAL	55.556%	540	0.0	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6520 PE=4 SV=1
Q6CAS2_YARLI	55.945%	513	0.0	YALI0D00407p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D00407g PE=4 SV=1
A0A060TB79_BLAAD	52.399%	542	0.0	ARAD1B06138p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B06138g PE=4 SV=1
YIQ6_YEAST	44.567%	543	1.05e-166	Uncharacterized transporter YIL166C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YIL166C PE=1 SV=1
A0A1E4TFX3_9ASCO	26.419%	511	3.61e-46	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2334 PE=4 SV=1
MCA_01039_1	24.832%	447	6.91e-43	MCA_01039_1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0657

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
110 - 555
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 587

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  132 - 510
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. SSF103473 (MFS gene...)
  
  110 - 555
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
2. cd06174 (MFS)
  
  128 - 511
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

307 - 366

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

483 - 493

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

420 - 430

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

548 - 587

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

183 - 193

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 126

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

244 - 254

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

116 - 318

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

345 - 581

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

389 - 399

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

515 - 525

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

213 - 223

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

454 - 458

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

275 - 285

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

146 - 164

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

368 - 390

TMHMM
TMhelix (TMhelix)

288 - 310

TMHMM
TMhelix (TMhelix)

224 - 243

TMHMM
TMhelix (TMhelix)

494 - 513

TMHMM
TMhelix (TMhelix)

528 - 547

TMHMM
TMhelix (TMhelix)

459 - 481

TMHMM
TMhelix (TMhelix)

397 - 419

TMHMM
TMhelix (TMhelix)

253 - 275

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

526 - 547

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

494 - 514

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

400 - 419

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

367 - 388

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

224 - 243

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

431 - 453

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

127 - 145

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

459 - 482

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

286 - 306

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

165 - 182

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

255 - 274

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

194 - 212

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

1 - 28

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

142R

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

145I

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

146S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

147Q

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

149L

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

150S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

168Q

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

171F

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

172L

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

175F

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

179E

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

180L

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

182S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

183Q

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

229E

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

230G

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

233I

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

234A

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

237V

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

238S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

241S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

253L

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

254S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

257W

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

258T

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

264T

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

378Y

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

381T

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

382N

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

385S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

386S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

389T

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

402T

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

406T

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

410N

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

413H

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

417L

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

471G

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

472P

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

475H

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

479V

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

480G

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

483S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

495S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

496A

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

499Y

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

500N

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

503V

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

504Q

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

507S

putative substrate translocation pore
142R, 145I, 146S, 147Q, 149L, 150S, 168Q, 171F, 172L, 175F, 179E, 180L, 182S, 183Q, 229E, 230G, 233I, 234A, 237V, 238S, 241S, 253L, 254S, 257W, 258T, 264T, 378Y, 381T, 382N, 385S, 386S, 389T, 402T, 406T, 410N, 413H, 417L, 471G, 472P, 475H, 479V, 480G, 483S, 495S, 496A, 499Y, 500N, 503V, 504Q, 507S
CDD
cd06174 (MFS)

Protein sequence

>MIA_01019_1
MSSSPPKKKDDTNVLSFRASSSSDDEDVSEGVLYYNNYETFSEREGLINNKKSSVIRSFSVSEPSLEKSRNPFYGGKNHV
FADPEVAEHYRQIYNNAGYEGRFHFDPTLEWTKEQETKLLWKIEYKACFWACFMFFALQLDRGNISQALSDNMLSDLKLN
TNDYNAGQTIFLTVFLLSELPSQLIAKKMGPDRWIPAQMTLWSLVAISQSFISGKKSFFITRGLLGFLEGGFIAEIVSWL
SYFYTSSELPLRLSFFWTAGTLTTIGSSLIAFVILRLRNVGGWEGWRWLFFIEGFVTLVIGIASFFKMPASPVQTKTWFR
PNGWFTEFEEKLIVNRVLRDDPSKGDMHNRQAVSFKQLGESLLDYDLWPLYLIGLISYIPTNAVSSYFTLNLRQLGFSTF
YTNLLTIPPNVIHIILLISQTWLTEHLNERSFISSLQPLWVIPCGAVLAFWSGTLHNVWGTYTVLVILLSGPYIHAILVG
WCSRNSNAVRTRTVSAAVYNMFVQGGSVISSNIYRKDDAPYYKRGNRVIFILSVVSLFLILGTKAYYMWRNKRRDEIWGA
MTEEERIEYRKTTTDEGNKRLDFRFSH

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features