MIA_01017_1

Protein

Length

567 amino acids

Protein function

EGGNOG:	0QDJB	PGUG_05050	transporter
SGD closest match:	S000001428	YIL166C	Uncharacterized transporter YIL166C
CGD closest match:	CAL0000201100	orf19.6520	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
A0A0J9X651_GEOCN	68.336%	559	0.0	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA04s01748g PE=4 SV=1
UniRef50_A3LWD0	64.892%	507	0.0	Putative allantoate permease n=276 Tax=Dikarya TaxID=451864 RepID=A3LWD0_PICST
A0A1E3PQH2_9ASCO	58.363%	562	0.0	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_19598 PE=4 SV=1
A0A167D9I1_9ASCO	57.168%	565	0.0	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_906 PE=4 SV=1
A0A1D8PQZ7_CANAL	57.477%	555	0.0	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6520 PE=4 SV=1
Q6CAS2_YARLI	58.285%	513	0.0	YALI0D00407p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D00407g PE=4 SV=1
A0A060T3B5_BLAAD	53.626%	524	0.0	ARAD1C35992p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C35992g PE=4 SV=1
YIQ6_YEAST	44.902%	559	3.19e-177	Uncharacterized transporter YIL166C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YIL166C PE=1 SV=1
A0A1E4TFX3_9ASCO	26.860%	551	7.48e-53	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2334 PE=4 SV=1
MCA_01039_1	25.641%	429	1.81e-44	MCA_01039_1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0360

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
88 - 534
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 567

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  113 - 491
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. SSF103473 (MFS gene...)
  
  88 - 534
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
2. cd06174 (MFS)
  
  108 - 491
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

463 - 473

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

371 - 414

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

256 - 266

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

530 - 567

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 198

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

95 - 298

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

325 - 560

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

434 - 438

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

223 - 233

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

496 - 506

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

289 - 347

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

439 - 461

TMHMM
TMhelix (TMhelix)

508 - 530

TMHMM
TMhelix (TMhelix)

268 - 290

TMHMM
TMhelix (TMhelix)

416 - 435

TMHMM
TMhelix (TMhelix)

233 - 255

TMHMM
TMhelix (TMhelix)

348 - 370

TMHMM
TMhelix (TMhelix)

474 - 493

TMHMM
TMhelix (TMhelix)

204 - 223

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

267 - 288

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

415 - 433

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

439 - 462

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

474 - 495

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

234 - 255

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

348 - 370

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

507 - 529

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

199 - 222

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

1 - 22

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

122R

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

125I

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

126G

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

127Q

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

129L

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

130S

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

148Q

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

151F

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

152R

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

155F

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

159E

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

160L

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

162S

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

163Q

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

209E

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

210G

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

213I

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

214A

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

217V

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

218S

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

221S

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

233L

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

234S

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

237W

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

238T

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

244D

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

358Y

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

361T

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

362S

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

365S

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

366A

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

369T

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

382T

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

386T

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

390N

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

393H

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

397L

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

447V

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

450S

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

451G

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

454I

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

458L

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

459V

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

462C

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

473T

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

474V

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

479Y

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

480N

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

483V

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

484Q

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

487S

putative substrate translocation pore
122R, 125I, 126G, 127Q, 129L, 130S, 148Q, 151F, 152R, 155F, 159E, 160L, 162S, 163Q, 209E, 210G, 213I, 214A, 217V, 218S, 221S, 233L, 234S, 237W, 238T, 244D, 358Y, 361T, 362S, 365S, 366A, 369T, 382T, 386T, 390N, 393H, 397L, 447V, 450S, 451G, 454I, 458L, 459V, 462C, 473T, 474V, 479Y, 480N, 483V, 484Q, 487S
CDD
cd06174 (MFS)

Protein sequence

>MIA_01017_1
MASQNIEKNGTLVHSKSDDDFDKNKTYVSALSADNEDIYDSEAEQKLKRHKPFYGGKDHVFNDPEVADHYREIYEKATYE
GRFHFDPDFEWTPEEERKLLWKIELRACFWACVMFMALQLDRGNIGQALSDNMLKDLNLTTNDYNTGQTIFRLCFLAAEL
PSQLVSKKIGPDRWIPTQITIWSIVALCQSRLSGKGSFFATRALLGLLEGGFIADTVSWLSYFYTGYELPIRLSFFWTTL
TLTDICASLLAFGVLRMRGILGWEGWRWLFLLEGIFTLIIGLLSFIQLPPSPVQTKAWFRPNGWFTEFEEKLIVNRVLRD
DPSKGDMHNRQAVSLKQLWESLCDYDLWPLYLIGVVSYIPTSTVSAYLTLTLKQLGFSTFNTNLLTIPPNAVHIVLLLAQ
TWLTERINERTITSMLQPLWIIPCVGTLAFWSQSLTNVWGTYALLVVLLSGPYIHAILVGWCSRNSNTVRTRTVSAAVYN
MFVQTGSIIAANIYRKDDSPKYRRGNRVLFGIGFVSLVILIGTKIYYVWRNKSRDKIWNAMTLEEQHEYRKNTTDKGNKR
LDFRFAH

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features