MIA_00883_1

Protein

Length

557 amino acids

Protein function

EGGNOG:	0PGXG	FGSG_01571	hormone-sensitive lipase

Protein alignments

	%id	Aln length	E-value
MCA_02696_1	65.714%	560	0.0	MCA_02696_1
A0A0J9X8B2_GEOCN	51.318%	569	0.0	Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA05s00912g PE=4 SV=1
UniRef50_A0A0J9X8B2	51.318%	569	3.39e-180	Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X8B2_GEOCN
Q6C5J1_YARLI	41.276%	533	1.06e-109	YALI0E17655p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E17655g PE=4 SV=1
A0A1E4TG78_9ASCO	33.270%	529	4.26e-77	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_110684 PE=4 SV=1
A0A060TFA5_BLAAD	33.663%	101	4.50e-10	ARAD1D21538p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D21538g PE=4 SV=1
A0A161HG22_9ASCO	20.270%	296	1.08e-07	Putative esterase OS=Sugiyamaella lignohabitans GN=AWJ20_4452 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8782
Predicted cleavage: 49

Protein family membership

None predicted.

Domains and repeats

Domain
156 - 536
Alpha/Beta hydrolase fold (IPR029058)
Alpha/beta hydrolase fold-3 (IPR013094)

1 100 200 300 400 500 557

Detailed signature matches

IPR029058

Alpha/Beta hydrolase fold
1. SSF53474 (alpha/bet...)
  
  185 - 340
  
  SUPERFAMILY
  SSF53474 (alpha/beta-Hydrolases)
  
  396 - 518
  
  SUPERFAMILY
  SSF53474 (alpha/beta-Hydrolases)
2. G3DSA:3.40.50...
  
  156 - 536
  
  GENE3D
  G3DSA:3.40.50.1820 (G3DSA:3.40.50.1820)
IPR013094

Alpha/beta hydrolase fold-3
1. PF07859 (Abhydrolase_3)
  
  397 - 470
  
  Pfam
  PF07859 (Abhydrolase_3)
  
  205 - 345
  
  Pfam
  PF07859 (Abhydrolase_3)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

58 - 77

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
NON_CYTOPLASM... (N...)

98 - 557

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

26 - 40

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 25

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

22 - 25

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

8 - 21

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 7

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)
TMhelix

80 - 97

TMHMM
TMhelix (TMhelix)

41 - 60

TMHMM
TMhelix (TMhelix)

7 - 26

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

41 - 57

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

78 - 97

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

Protein sequence

>MIA_00883_1
MAETRTRVITVAFFWYLLSILGPKGGPPGFEKFNRWATRRFTAWQLSILTLVGYYVVRNIDAILNLHPKMARHKIYEPKF
ETAVTVMTAMTAGFMTAKSLRPKALRDLASLVFAGYYLFTPDHAMEKVRKFNENPSVEGIRTSFEIMDNPYLDLVGSLLR
PRLRGAQGEIFHVPRPKSSVYLAPVELELWYDKPLSQLKSEKKIIFHIHGGGFISNTPRLHADSLTAWARQTQVPIIAIN
YRRAPEYPFPYAVDECFDAYTAMVESRGLCFGIKSNIPPRVVITGDSAGGNFSAVLMIKIIMSGNKALRDPVDALVLTYP
ALDLSPVGCYGEREMEFFRQEANDDRDTGIFETRAEVVELYKSGVHPVSMEHLVVAGTPYVDVNKNTPLSLSSRVLFMSD
RVIPAEGLYVMVIMYIGTDRGIDFHNDPLVSPLWANDELLAQFPRCYVTCGTCDPLVDDTVIFTSRLRNARLSKKPNLDL
TEDIIRARLVKGVSHGFLQFDTIYPEAKSIYKMIGSWFLDAFERAEQEPHLTVQEYREILSTSTVDTYRYNNPFPGY

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0016787 hydrolase activity

Cellular Component