Protein

MIA_00856_1

Length
608 amino acids

Browser: contig01:2418934-2420821+

Protein function

EGGNOG:0PFK9NEM1Nuclear envelope morphology protein
SGD closest match:S000001046NEM1Nuclear envelope morphology protein 1
CGD closest match:CAL0000188900orf19.4657Nem1-Spo7 phosphatase catalytic subunit

Protein alignments

%idAln lengthE-value
A0A0J9X8U1_GEOCN66.332%1991.28e-79Similar to Saccharomyces cerevisiae YHR004C NEM1 Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme OS=Geotrichum candidum GN=BN980_GECA05s04872g PE=4 SV=1
UniRef50_A0A0J9X8U166.332%1992.61e-76Similar to Saccharomyces cerevisiae YHR004C NEM1 Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X8U1_GEOCN
MCA_05619_155.745%2354.74e-76MCA_05619_1
A0A060T8K8_BLAAD71.186%1771.57e-78ARAD1D07832p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D07832g PE=4 SV=1
Q6CD87_YARLI61.413%1843.08e-76YALI0C02849p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C02849g PE=4 SV=1
A0A167FRA9_9ASCO65.746%1812.64e-77Nem1-Spo7 phosphatase catalytic subunit NEM1 OS=Sugiyamaella lignohabitans GN=NEM1 PE=4 SV=1
A0A1E3PJQ8_9ASCO64.972%1775.53e-78Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_24071 PE=4 SV=1
NEM1_YEAST52.062%1941.19e-57Nuclear envelope morphology protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NEM1 PE=1 SV=1
A0A1D8PL92_CANAL50.237%2112.71e-51Nem1-Spo7 phosphatase catalytic subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4657 PE=4 SV=1
A0A1E4TDD1_9ASCO60.544%1474.96e-53Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_29190 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.8692
Predicted cleavage: 30

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 608

Detailed signature matches

  1. Domain IPR023214
    HAD-like domain
    1. SSF56784 (HAD-like)
    2. G3DSA:3.40.50...
  2. Domain IPR004274
    FCP1 homology domain
    1. SM00577 (forpap2)
    2. PS50969 (FCP1)
    3. PF03031 (NIF)
  3. Domain IPR011948
    Dullard phosphatase domain, eukaryotic
    1. TIGR02251
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TRANSMEMBRANE (Tran...)
  4. cd07521 (HAD_FCP1-like)
  5. mobidb-lite (disord...)

Residue annotation

  1. HAD signature moti...
  2. active site cd07521
  3. HAD signature moti...
  4. HAD signature moti...
  5. HAD signature moti...

Protein sequence

>MIA_00856_1
MNSIQFISNRVDRVINHTTPPSTPIRSRSVVSLTRSRDENDKRNFNDDDDSNEVLTYRQKQSHLELIDESLELALQHKQY
QRQYHLQPRSFSSPALHSLESKTRSPLSSLSKDKDDTTLKTENDKDNSNLNKEQSQQSQSLFHKVLTFATSILLFIPFRI
YNFLIHIAILLHINSKTVNKTTEMGEMTKSTSNSSDVVYDVNSPTSLSSQQTFKRLLASFLGWIPFFSTKFSSSPASTPP
TAVAKTQQDNVKIQPDNNNNNTTTTTTTTAISIPSTPKQKIKSKSKPSTPGTLEKPRTRARNSSSSTGNRPQPIKSNSGT
GTNTPTKTELDSSTQQEHDTFNSTPKRRKSPLSYAFKFPRIYSPPRPLLPPQTFKPLSLWQLLSLSLSGPKPSEKQEELN
TRGTKTTTPGTSSIPLQMSSNANAIHYRRLKKKTLILDLDETLIHTLSRAPGFSQGSMVEVKLNSYATLYTVLKRPFCDE
FLQTVSQWYNLVVFTASVQAYADPMIDWLEKDRKYFVQRYYRQHCTQTNMGYVKDLGAVDPDLSNVMIIDNSPISYLQHK
ANGIGIEGWINDPSDNSLLALIPFLAAIRFSTDVRSILGLKAGDAAFT

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016791 phosphatase activity

Cellular Component

None predicted.