Protein

MIA_00792_1

Length
1,224 amino acids

Browser: contig01:2242284-2245959-

Protein function

EGGNOG:0QDD9Transcription factor
SGD closest match:S000005558HMS1Probable transcription factor HMS1
CGD closest match:CAL0000181382CPH2Transcription factor CPH2

Protein alignments

%idAln lengthE-value
MCA_05521_156.312%8080.0MCA_05521_1
A0A0J9X782_GEOCN50.062%8050.0Similar to Saccharomyces cerevisiae YOR032C HMS1 Basic helix-loop-helix (BHLH) protein with similarity to myc-family transcription factors OS=Geotrichum candidum GN=BN980_GECA04s04014g PE=4 SV=1
UniRef50_A0A0J9X78250.062%8050.0Similar to Saccharomyces cerevisiae YOR032C HMS1 Basic helix-loop-helix (BHLH) protein with similarity to myc-family transcription factors n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X782_GEOCN
A0A1E3PIP4_9ASCO34.068%5909.18e-78Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83314 PE=4 SV=1
A0A060T433_BLAAD36.775%5523.87e-71ARAD1C01452p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C01452g PE=4 SV=1
A0A167FLN0_9ASCO31.139%5628.35e-47Hms1p OS=Sugiyamaella lignohabitans GN=HMS1 PE=4 SV=1
Q6C906_YARLI32.302%2919.15e-36YALI0D15334p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D15334g PE=4 SV=1
A0A1E4TKX0_9ASCO29.285%6012.47e-27Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_882 PE=4 SV=1
CPH2_CANAL66.667%877.89e-27Transcription factor CPH2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CPH2 PE=1 SV=1
HMS1_YEAST45.283%1068.00e-19Probable transcription factor HMS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HMS1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0012

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1224

Detailed signature matches

  1. Domain IPR011598
    Myc-type, basic helix-loop-helix (bHLH) domain
    1. PS50888 (BHLH)
    2. G3DSA:4.10.28...
    3. SSF47459 (HLH, heli...)
    4. SM00353 (finulus)
    5. cd00083 (HLH)
    6. PF00010 (HLH)
  2. Domain IPR019006
    Sterol regulatory element-binding protein 1, C-terminal
    1. PF09427 (DUF2014)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. G3DSA:1.10.11...
  4. NON_CYTOPLASM... (N...)
  5. TRANSMEMBRANE (Tran...)
  6. mobidb-lite (disord...)

Residue annotation

  1. DNA binding region...
  2. E-box/N-box specif...
  3. dimerization inter...

Protein sequence

>MIA_00792_1
MEEPNPIIPFEFADCDAFLASLDDNSTTILSQKQSDLLRFQQIQLQQQQLRQQQLQQQASPSSTSSSLSSSPISTTPITQ
SQATFPIQPTAQQQHPIMIGQPSINDFVSMSGDVSADPSVLPSTWSPQDSPARPGTLYSADPFALQQPQQQQQQPQPLPQ
LLPSQQQHQQPLPTQQPQPYSNNSTPLSSPLSVASMPDPQSAAAAAAAAAAAAAAAAGFINNDMIYNNAMAISNLAYPSA
GSVSVSSTPVAYPITPPYPSAPSVPASDVGDSGSPDFNQDYAAAAAAAAAANGNSNPVYSGIIPSSVGPSADVLSANLMQ
GSIIQQQQQQQQQQLMSQQRSVYPDLSIGSLAPPQPSTSATASPNNASVAPSTQFTYGKDEQAISPHSYANNQSPDSPQS
VGSPQSPSEIKEEDDFFSSNTSSSRKNSIKRERQGSAITKGNKITKPKKEKTSHNMIEKRYRTNINDKILALRDCVPSLR
CVVNGTPRTAEELEGLTPASKLNKATVLTKATEYILHLQKRNALLLQELSDLRNNRSDSGSPNSPNDMAPTAGLANMPIM
QAYPTLNGQQLQQQQQQPDIRQMFNGNNFTSKVMMCSMAGLMGAGLMGEGSDTQGLSILPYSNIFSNLKIGTWDSSSLIY
ALKLVLILGTVLYVFAPILISSFSSEKAKEPSPTFAAYAEESEDENELQTLNFELSDIRKQTWLNNSRYLNIPTSSISSQ
ISAHARTLAQILSIVVLGPEGYDMLFGSAEQTLSAKRSFLNVAIDAQLCGGDNDTISNKDTTRSSLLYTLGQSFLLPPTP
VRYFTQAMQINVVCHDVPIFDMIGTHLSAYFLSKARATAVSLEEDSLTDEDDGTHVAKHIVALLEFDGLFTPRTNQRLYN
VAFGNPISEGCPLGDDDEGYASVLTDKSICSAHDVLAALHANSLLHDVLLGVLENDEIDFRKLELSAKISPPRSIVARRV
AIAEALLLGPKDASYAKNAMEMLKEELNQQAWINRELSSFPPTLTSVHEFGDLSSTVSHSRSNSHHTINTVTLSAGIVSE
IDEEEEESLFSSSESIMSNTSSNEYTEDHVSESEASVSTERDGDRVAFLSTSVKSSSTPFAVSQDSRLGIRFSLVMCYLA
RNMRGPAFQLLQKVEINKLESIGLLGFVAMWKVLTEMYERKYISNNRHKLEDLAAIARIWLGGNIGAEEGISLDRLRYLA
GESVAMSKFFGGYESELDEGYGTQ

GO term prediction

Biological Process

GO:0032933 SREBP signaling pathway
GO:0045944 positive regulation of transcription from RNA polymerase II promoter

Molecular Function

GO:0046983 protein dimerization activity

Cellular Component

None predicted.