Protein

MIA_00766_1

Length
833 amino acids

Browser: contig01:2172619-2175121+

Protein function

EGGNOG:0PHXJFG02477.1Nadh dehydrogenase
SGD closest match:S000004753NDE1External NADH-ubiquinone oxidoreductase 1, mitochondrial
CGD closest match:CAL0000200307NDE1NADH-ubiquinone reductase (H(+)-translocating)

Protein alignments

%idAln lengthE-value
MCA_06152_156.702%7460.0MCA_06152_1
A0A0J9XJV7_GEOCN53.911%7160.0Similar to Saccharomyces cerevisiae YMR145C NDE1 Mitochondrial external NADH dehydrogenase, a type II NAD(P)H:quinone oxidoreductase OS=Geotrichum candidum GN=BN980_GECA26s00318g PE=4 SV=1
A0A1E3PJF0_9ASCO50.704%7100.0FAD/NAD(P)-binding domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83435 PE=4 SV=1
A0A060T610_BLAAD48.458%7780.0ARAD1B07172p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B07172g PE=4 SV=1
UniRef50_K0KK3848.837%6880.0NADH dehydrogenase n=19 Tax=Saccharomycetales TaxID=4892 RepID=K0KK38_WICCF
Q6C6X0_YARLI48.911%6890.0YALI0E05599p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E05599g PE=4 SV=1
A0A167F3A9_9ASCO57.273%4404.65e-171NADH-ubiquinone reductase (H(+)-translocating) NDE1 OS=Sugiyamaella lignohabitans GN=NDE1 PE=4 SV=1
A0A1E4TC46_9ASCO53.613%4295.23e-150Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3963 PE=4 SV=1
Q5AEC9_CANAL35.159%3472.09e-56NADH-ubiquinone reductase (H(+)-translocating) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NDE1 PE=4 SV=1
NDH1_YEAST40.785%3311.80e-55External NADH-ubiquinone oxidoreductase 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NDE1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9972
Predicted cleavage: 157

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 833

Detailed signature matches

  1. Domain IPR023753
    FAD/NAD(P)-binding domain
    1. PF07992 (Pyr_redox_2)
    2. G3DSA:3.50.50.60
    3. SSF51905 (FAD/NAD(P...)
  2. Domain IPR011992
    EF-hand domain pair
    1. SSF47473 (EF-hand)
  3. Domain IPR002048
    EF-hand domain
    1. SM00054 (efh_1)
    2. PS50222 (EF_HAND_2)
    3. PF13405 (EF-hand_6)
  4. SITE IPR018247
    EF-Hand 1, calcium-binding site
    1. PS00018 (EF_HAND_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.10.23...
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)

Protein sequence

>MIA_00766_1
MTLLPRLLSKISPPATPLWQSSSRPLRSSLHNAILSANASSLAPPSQLTSPAPPAPTRSLLLPLARTAFRPAATSHRRPL
YPTATTPCGFFAHPQPLAQLPSVSSQLRLLSTTRSLNNSGKPAASTPPSTVKSTLKLFELKTWHFFRLILQSIGVVVFSI
AGLFFLFFLYDATTYAGDDDSANGSPAGKTIRVPYFALHPQRGGPKNLPIFDACLDDFDSPEMQLETTRPRLVVLGTGWG
TVALLKQLYANDYDVIVVSPTNYFLFTPLLPSATVGTLETRSLVQPIRTMLRSINAHFLQAEAVDVLFNEQLVEVAATNP
ETGATENFYIPYDKVVVGVGSVSNKHGVDGLQHCLKLKTVDDVTSIRTKIVRNIEAACLPTTSDEERKRLLSFVICGGGP
TGVELAAELFDVVREDLTKRYPKILRSEVSVHIVQSRSHILNTYDQSISNYAEKRFGKDGVDVITNSRVNKILPDRVVFT
QVNDDGTKSLKELPYGICIWSTGVDKAPLTRAITERLGKNYQRNRRAIETDAHLRIIGAPLGTAYAIGDCSTVRTSIADE
IERLLRDGVLNSKRYYRMELEDTVAMPVDDHPLAPHPVEEHLALPITAQPVTDPSQKSLPSLDKLEEAISEPTTSHHHLQ
PRRHIHAVEDDKDFSNLRLTFDDFLVLARTIRSKFPQTRVHISRLEDLFRQYDHDGSGTLSYAELEEMLAAIDKKITSLP
ATAQRAFQQGKYLGRKMGRLVRLSDRLRVADVKYGDVDASICKPFMYHHLGSLAYIGNAAVFDMNGHSFFGGLLAMYAWR
AAYFAQTVSFRTRALICMDWLKRGLFGRDLSGV

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0005509 calcium ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.