MIA_00568_1

Protein

Length

552 amino acids

Protein function

EGGNOG:	0PFSV	HXT1	transporter
SGD closest match:	S000002750	HXT7	High-affinity hexose transporter HXT7
CGD closest match:	CAL0000198671	HGT7	Hgt7p

Protein alignments

	%id	Aln length	E-value
MCA_03719_1	52.772%	487	8.44e-128	MCA_03719_1
A0A0J9XGJ5_GEOCN	42.227%	476	2.12e-93	Similar to Saccharomyces cerevisiae YHR096C HXT5 Hexose transporter with moderate affinity for glucose OS=Geotrichum candidum GN=BN980_GECA15s00725g PE=3 SV=1
UniRef50_A0A0J9X2L2	37.917%	509	6.22e-70	Similar to Saccharomyces cerevisiae YHR094C HXT1 Low-affinity glucose transporter of the major facilitator superfamily n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X2L2_GEOCN
A0A167EXF2_9ASCO	36.140%	487	2.70e-69	Hexose transporter HXT6 OS=Sugiyamaella lignohabitans GN=HXT6 PE=3 SV=1
A0A1E3PTG0_9ASCO	38.168%	393	3.88e-69	General substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_68500 PE=3 SV=1
Q6C152_YARLI	35.902%	532	6.46e-68	YALI0F19184p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F19184g PE=3 SV=1
HXT7_YEAST	37.852%	391	1.40e-62	High-affinity hexose transporter HXT7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HXT7 PE=1 SV=1
A0A1D8PG81_CANAL	34.694%	392	1.14e-57	Hgt7p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HGT7 PE=3 SV=1
A0A060TDA9_BLAAD	34.667%	375	4.48e-54	ARAD1B23166p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B23166g PE=3 SV=1
A0A1E4TA60_9ASCO	27.344%	384	8.56e-23	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_126349 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0425

Protein family membership

Major facilitator, sugar transporter-like (IPR005828)
- Sugar/inositol transporter (IPR003663)

Domains and repeats

Domain
33 - 518
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 552

Detailed signature matches

IPR005828

Major facilitator, sugar transporter-like
1. PF00083 (Sugar_tr)
  
  47 - 521
  
  Pfam
  PF00083 (Sugar_tr)
IPR003663

Sugar/inositol transporter
1. TIGR00879
  
  17 - 513
  
  TIGRFAMs
  TIGR00879 (TIGR00879)
2. PR00171 (SUGRTRNSPORT)
  
  319 - 329
  
  PRINTS
  PR00171 (SUGRTRNSPORT)
  
  422 - 443
  
  PRINTS
  PR00171 (SUGRTRNSPORT)
  
  52 - 62
  
  PRINTS
  PR00171 (SUGRTRNSPORT)
  
  150 - 169
  
  PRINTS
  PR00171 (SUGRTRNSPORT)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  44 - 510
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  33 - 518
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  48 - 507
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

112 - 122

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

507 - 552

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

241 - 308

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

445 - 455

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 41

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

172 - 182

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

375 - 380

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

35 - 257

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

282 - 533

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

406 - 416

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

67 - 85

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

331 - 349

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

480 - 484

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

206 - 216

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

145 - 149

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

423 - 445

TMHMM
TMhelix (TMhelix)

218 - 240

TMHMM
TMhelix (TMhelix)

149 - 171

TMHMM
TMhelix (TMhelix)

381 - 403

TMHMM
TMhelix (TMhelix)

458 - 480

TMHMM
TMhelix (TMhelix)

183 - 205

TMHMM
TMhelix (TMhelix)

485 - 507

TMHMM
TMhelix (TMhelix)

352 - 374

TMHMM
TMhelix (TMhelix)

88 - 110

TMHMM
TMhelix (TMhelix)

40 - 62

TMHMM
TMhelix (TMhelix)

310 - 332

TMHMM
TMhelix (TMhelix)

123 - 145

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

217 - 240

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

86 - 111

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

123 - 144

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

456 - 479

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

150 - 171

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

417 - 444

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

381 - 405

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

42 - 66

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

485 - 506

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

350 - 374

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

309 - 330

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

183 - 205

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

Residue annotation

putative substrate...

59T

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

62I

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

63S

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

64G

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

66L

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

67N

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

84P

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

87Y

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

88L

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

91S

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

95G

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

96L

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

98V

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

99G

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

160I

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

161G

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

164S

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

165A

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

168P

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

169M

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

172S

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

185V

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

186S

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

189Q

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

190L

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

196I

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

321L

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

324I

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

325N

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

328F

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

329Y

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

332T

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

352P

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

356S

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

360G

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

363N

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

367T

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

430V

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

433A

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

434G

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

437A

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

441F

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

442V

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

445S

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

457A

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

458I

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

461A

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

462V

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

465N

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

466W

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

469N

putative substrate translocation pore
59T, 62I, 63S, 64G, 66L, 67N, 84P, 87Y, 88L, 91S, 95G, 96L, 98V, 99G, 160I, 161G, 164S, 165A, 168P, 169M, 172S, 185V, 186S, 189Q, 190L, 196I, 321L, 324I, 325N, 328F, 329Y, 332T, 352P, 356S, 360G, 363N, 367T, 430V, 433A, 434G, 437A, 441F, 442V, 445S, 457A, 458I, 461A, 462V, 465N, 466W, 469N
CDD
cd06174 (MFS)

Protein sequence

>MIA_00568_1
MIDFVNIDLNNFDTLVNTTSIHKVDSKQTMANPPYFKKTHNILISGTIAIGGIILGYDTGSISGMLNMPSYIHAIGVLDR
SVSPPIYLIPSWCSGLVVGAVSLGGLFGSFFFGKAADRFGRRLTLAGTTGLLSISTLSQGTGYMHWPIVFAARFCTGLAI
GGISAVCPMYISETAASPSLQTLLVSSFQLLLTIGILIGQGVAFGASTLPNWSIWQFMFPLLGILLFSMPLCAISMFGII
PESTKYLASNGKISEAKKSIAQVTGLSADDPYIADQVAVAVAAHEATQSESAASWKQVFSVSSKMRYRVILAIAVMMLQQ
LSGINYFFYYGTSLFKEICGGGASEGSGGLSPYATSMILGSVNIIGTICLLPLVCKFPRRIVLLTGTAVMLAAFIAFSTL
GQFFLHNAATHTINPAVGYTMIGLVCVFIVGFAGTWAPCAFVVISEMFPLHHFRSMAISLAVASNWFVNSCITFISPIAT
RHLGYAFGYVFSAFLVLAMAVVYLFVYETKGLLPEQIEEMFGSTEVTPRNSESWRQRKVFANESSRCTEKVV

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0022857 transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity

Cellular Component

GO:0016020 membrane
GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features